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Archive for the ‘bioengineering’ category: Page 6

Jan 10, 2024

Scientists engineer smart bacteria that live in your skin to treat acne

Posted by in categories: bioengineering, biotech/medical

Cutting-edge research engineers skin bacteria to treat acne, presenting a novel therapeutic approach for skin conditions.


In a study led by the Translational Synthetic Biology Laboratory Department of Medicine and Life Sciences (MELIS) at Pompeu Fabra University, an international research team has successfully engineered Cutibacterium acnes, a type of skin bacterium, to secrete a therapeutic molecule to treat acne symptoms. This innovative approach holds promise for addressing skin alterations and other diseases using living therapeutics.

Engineering smart skin bacteria

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Jan 4, 2024

Skin-on-a-chip: Modeling an innervated epidermal-like layer on a microfluidic chip

Posted by in categories: bioengineering, biotech/medical, computing, neuroscience

Year 2023 face_with_colon_three


Bioengineers and tissue engineers intend to reconstruct skin equivalents with physiologically relevant cellular and matrix architectures for basic research and industrial applications. Skin pathophysiology depends on skin-nerve crosstalk and researchers must therefore develop reliable models of skin in the lab to assess selective communications between epidermal keratinocytes and sensory neurons.

In a new report now published in Nature Communications, Jinchul Ahn and a research team in , bio-convergence engineering, and therapeutics and biotechnology in South Korea presented a three-dimensional, innervated epidermal keratinocyte layer on a to create a sensory neuron-epidermal keratinocyte co-culture model. The maintained well-organized basal-suprabasal stratification and enhanced barrier function for physiologically relevant anatomical representation to show the feasibility of imaging in the lab, alongside functional analyses to improve the existing co-culture models. The platform is well-suited for biomedical and pharmaceutical research.

Continue reading “Skin-on-a-chip: Modeling an innervated epidermal-like layer on a microfluidic chip” »

Jan 3, 2024

Synthetic biology breakthrough fixes CO2 from the air better than nature

Posted by in categories: bioengineering, biological, chemistry, sustainability

Scientists at the Max Planck Institute have developed a synthetic pathway that can capture CO2 from the air more efficiently than in nature, and shown how to implement it into living bacteria. The technique could help make biofuels and other products in a sustainable way.

Plants are famous for their ability to convert carbon dioxide from the air into chemical energy to fuel their growth. With way too much CO2 in the atmosphere already and more being blasted out every day, it’s no wonder scientists are turning to this natural process to help rein levels back in, while producing fuels and other useful molecules on the side.

In the new study, Max Planck scientists developed a brand new CO2-fixation pathway that works even better than nature’s own tried-and-true method. They call it the THETA cycle, and it uses 17 different biocatalysts to produce a molecule called acetyl-CoA, which is a key building block in a range of biofuels, materials and pharmaceuticals.

Jan 2, 2024

EARD 2023 Panel Discussion: Is Aging Truly Reversible?

Posted by in categories: bioengineering, neuroscience, quantum physics

A nice talk. At 18 minutes dude says healthspan is way more important than lifespan. Never mind that large sign behind him that says lifespan. But, not to knock it too much, yes healthspan is important too.


Dr. Oliver Medvedik, Dr. Aubrey de Grey, Dr. Peter Fedichev, Dr. Hanadie Yousef, Reason, and Dr. Hans Keirstead debate whether or not aging is truly reversible at the Longevity+DeSci Summit NYC (EARD 2023). \
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Summary\
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Dr. Oliver Medvedik earned his Ph.D. at Harvard Medical School in the Biomedical and Biological Sciences program. Oliver is presently the Director of the Kanbar Center for Biomedical Engineering at The Cooper Union, where he carries out research on improving gene targeting in mammalian cells, enzymatic oligonucleotide synthesis, and other bioengineering projects with undergraduate and graduate students at the Albert Nerken School of Engineering. Dr. Medvedik is also the co-founder of the community biotechnology laboratory, Genspace, located in Brooklyn, where he continues to serve on its board of directors. In addition, Dr. Medvedik is also co-founder and vice-president of the non-profit organization LEAF (Life Extension Advocacy Foundation), where he serves on the board of directors.\
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➡️: / oliver-medvedik-4067016 \
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Dr. Aubrey de Grey is a pillar of the longevity community. Dr. de Grey works on the development of medical innovations that can postpone all forms of age-related ill-health. His main focus is on rejuvenation: that is, the active repair of the various types of molecular and cellular damage which eventually cause age-related disease and disability, as opposed to the mere retardation of the accumulation of such damage. He is currently the President and Chief Scientific Officer of the Longevity Escape Velocity (LEV) Foundation. \
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➡️: https://www.levf.org\
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Dr. Peter Fedichev is an entrepreneur and scientist who co-founded three biotech companies: Quantum Pharmaceuticals, a drug discovery company, and Gero, a longevity startup, and GlyNeura, a biotech-pharma company aiming to cure Neurodegenerative Diseases. His scientific background lies in the fields of condensed matter physics, biophysics, and bioinformatics. His dream is to beat aging and experience life in space.\
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➡️: https://gero.ai\
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Dr. Handie Yousef is a leading expert on the biology of aging and mechanisms underlying tissue degeneration with over two decades of experience in biomedical research. In 2018, she launched Juvena Therapeutics, a venture-backed biotechnology company mapping the therapeutic potential of secreted proteins to develop biologics that prevent, reverse, and cure chronic, metabolic, and age-related diseases.\
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➡️: https://www.juvenatherapeutics.com\
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Reason is co-founder and CEO of Repair Biotechnologies. He has been an active angel investor in the longevity industry since its earliest days, with investments including Oisin Biotechnologies and Leucadia Therapeutics. He is a long-standing and well-connected patient advocate for aging research, involved in numerous fundraising and outreach initiatives conducted by organizations such as the Methuselah Foundation and SENS Research Foundation since the early 2000s. He is also the founder and writer of Fight Aging!, a noted news and commentary website in the biotechnology community. \
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➡️: https://www.repairbiotechnologies.com\
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Dr. Hans Keirstead is an internationally known stem cell expert and has led therapy development for cancer, immune disorders, motor neuron diseases, spinal cord injury, and retinal diseases. He is the Chairman and CEO of AIVITA Biomedical. Dr. Keirstead’s work in spinal cord injury earned him the distinction of being one of the 100 top scientists of the year in Discover Magazine. He was featured on 60 Minutes in a full segment covering his treatment for spinal cord injury. Dr. Keirstead and his research have also appeared in Newsweek, Inc. Magazine, WIRED, Esquire, The NY Times, TIME Magazine, Men’s Vogue, Science, and The American Spectator, amongst other national publications.\
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➡️: / hanskeirstead \
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Jan 1, 2024

A global dataset of pandemic- and epidemic-prone disease outbreaks

Posted by in categories: bioengineering, biotech/medical, genetics, nanotechnology

I believe nanomachines or new advanced rna antivirals that can target one’s own variants of viruses will be game changers to prevent future global pandemics. Also eventually new genetic engineering could allow for the end to all viruses with some sorta Omni vaccine.


Measurement(s) Pandemic-and epidemic-prone disease outbreaks Technology Type(s) Text mining using R Sample Characteristic — Organism Disease outbreaks Sample Characteristic — Environment spatiotemporal region Sample Characteristic — Location Global.

Dec 30, 2023

The LIFE-EXTENSION Doctor: “The ONE thing that’s increasing your chance of early-death by 170.8%!”

Posted by in categories: bioengineering, biotech/medical, life extension

In this new episode Steven sits down with the physician and longevity expert, Dr Peter Attia. 0:00 Intro 03:26 What is your mission? 06:52 Medicine 3.0 14:51 When should we really think about diseases? 23:14 What role does trauma play in longevity? 47:24 The 5 health deterioration 50:16 Proof exercise is important 01:04:48 Body deterioration can be slowed down 01:08:38 How much exercise should we be doing? 01:14:03 The importance of stability 01:20:59 We’ve engineered discomfort out of our lives 01:26:29 Sugar 01:34:16 Misconceptions about weight loss 01:45:13 Alcohol 01:49:13 Sleep 01:52:35 Hormone replacement therapy 01:57:07 Hair loss 01:59:48 The last guests question You can purchase Dr Attia’s new book, ‘Outlive: The Science and Art of Longevity’, here — https://amzn.to/3FUD6ok Follow Dr Attia: Instagram: https://bit.ly/3rBMyJ7 Twitter: https://bit.ly/44DkrYF YouTube: https://bit.

Dec 28, 2023

CRISPR Gene Editing Had a Breakthrough Year—and It’s Only Getting Started

Posted by in categories: bioengineering, biotech/medical

CRISPR had a huge year. Even better, it’s still a work in progress, with the potential to reshape biotechnology for decades to come.

Dec 28, 2023

Ep. 20: J. Storrs Hall — Bringing Back A Future Past With Flying Cars, Nano-Robots and Multi-Level Cities By Nurturing A Techno-Optimist Culture and a Unleashing Second Nuclear Age

Posted by in categories: bioengineering, economics, genetics, information science, nanotechnology, robotics/AI

An interview with J. Storrs Hall, author of the epic book “Where is My Flying Car — A Memoir of Future Past”: “The book starts as an examination of the technical limitations of building flying cars and evolves into an investigation of the scientific, technological, and social roots of the economic…


J. Storrs Hall or Josh is an independent researcher and author.

Continue reading “Ep. 20: J. Storrs Hall — Bringing Back A Future Past With Flying Cars, Nano-Robots and Multi-Level Cities By Nurturing A Techno-Optimist Culture and a Unleashing Second Nuclear Age” »

Dec 27, 2023

Why ‘resurrection biology’ is gaining traction around the world

Posted by in categories: bioengineering, biotech/medical, existential risks, genetics

Resurrection biology — attempting to bring strings of molecules and more complex organisms back to life — is gaining traction in labs around the world.

The work is a far cry from the genetically engineered dinosaurs that escape in the blockbuster movie “Jurassic Park,” although for some scientists the ultimate goal is de-extinction and resurrecting animals and plants that have been lost.

Other researchers are looking to the past for new sources of drugs or to sound an alarm about the possibility of long-dormant pathogens. The field of study is also about recreating elements of human history in an attempt to better understand how our ancestors might have lived and died.

Dec 24, 2023

The Genetic Revolution: The Manipulation of Human DNA | Documentary

Posted by in categories: bioengineering, biotech/medical, education, genetics

The Genetic Revolution is a compelling science documentary that invites viewers into the groundbreaking world of DNA manipulation and genetic engineering. This intriguing documentary showcases the innovative science behind genetic modifications and chronicles a diverse team of scientists from around the world as they utilize advanced DNA editing technologies like CRISPR in ways previously deemed unthinkable.\

With its exploration into the rapidly evolving science of DNA editing, \.

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