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Category: bioengineering – Page 20

Macquarie To Invest Up To $5 Billion In Applied Digital AI Data Centers

In today’s AI news, Macquarie will invest up to $5 billion in data centers being built by artificial-intelligence infrastructure company Applied Digital, adding to the Australian bank’s substantial AI-related investments.

And, President Joe Biden will issue an executive order on Tuesday to provide federal support to address massive energy needs for fast-growing advanced artificial intelligence data centers, the White House said.

The order calls for leasing federal sites owned by Defense and Energy departments to host gigawatt-scale AI data centers and new clean power facilities — to address enormous power needs on a short time frame.

Then, Microsoft is creating a new engineering group that’s focused on artificial intelligence. Led by former Meta engineering chief Jay Parikh, the new CoreAI – Platform and Tools division will combine Microsoft’s Dev Div and AI platform teams together to focus on building an AI platform and tools.

S strategy to enhance its AI capabilities across hybrid cloud environments.” + In videos, Snowflake CEO Sridhar Ramaswamy announces a new “upskill” initiative on AI as they work to address a global skills shortage. He joins Caroline Hyde on “Bloomberg Technology” to discuss the companies investment in educating people on AI skills.

Then Eleven Labs’ Louis Jordan demonstrates a conversational AI voice agent that can be integrated with Stripe to promote purchases, issue refunds, apply coupons and credits as well as many other payment related transactions with customers. Louis remarks that this is the future of in-app customer service.

And, did you know the U.S. nurse labor market is over $600 billion annually, but the dedicated software market for nurses is almost zero? In this episode, a16z General Partners Alex Rampell, David Haber, and Angela Strange discuss how AI is revolutionizing labor by automating tasks traditionally done by humans.

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DNA nanorobots that can alter artificial cells offer a new tool for synthetic biology

The shape and morphology of a cell play a key role in the biological function. This corresponds to the principle of “form follows function,” which is common in modern fields of design and architecture. The transfer of this principle to artificial cells is a challenge in synthetic biology. Advances in DNA nanotechnology now offer promising solutions. They allow the creation of novel transport channels that are large enough to facilitate the passage of therapeutic proteins across cell membranes.

In this emerging field, Prof. Laura Na Liu, Director of the 2nd Physics Institute at the University of Stuttgart and Fellow at the Max Planck Institute for Solid State Research (MPI-FKF), has developed an innovative tool for controlling the shape and permeability of lipid membranes in synthetic cells. These membranes are made up of that enclose an aqueous compartment and serve as simplified models of biological membranes. They are useful for studying membrane dynamics, protein interactions, and lipid behavior.

The work is published in Nature Materials.

Speed Unleashed: How a Tiny Quantum Switch Is Supercharging Data Centers

Researchers at the university of pennsylvania.

The University of Pennsylvania (Penn) is a prestigious private Ivy League research university located in Philadelphia, Pennsylvania. Founded in 1740 by Benjamin Franklin, Penn is one of the oldest universities in the United States. It is renowned for its strong emphasis on interdisciplinary education and its professional schools, including the Wharton School, one of the leading business schools globally. The university offers a wide range of undergraduate, graduate, and professional programs across various fields such as law, medicine, engineering, and arts and sciences. Penn is also known for its significant contributions to research, innovative teaching methods, and active campus life, making it a hub of academic and extracurricular activity.

Synthetic beads mimic critical process in cell division, opening new paths for biomachines

In a study that could help scientists better understand and manipulate cell division, RIKEN biologists have engineered artificial structures that replicate one of life’s most crucial processes—the precise division of packages of DNA known as chromosomes.

When a cell starts splitting into two , its align. The process of chromosome alignment can be likened to a high-stakes game of tug-of-war.

In a healthy cell, chromosomes line up at the center, each pulled by fibers extending from opposite sides of the cell. These fibers attach to kinetochores—anchors that ensure chromosomes are evenly pulled apart during —at the center of the dividing structures.

Discovery of new skeletal tissue advances regenerative medicine potential

An international research team led by the University of California, Irvine has discovered a new type of skeletal tissue that offers great potential for advancing regenerative medicine and tissue engineering.

Most cartilage relies on an external extracellular matrix for strength, but “lipocartilage,” which is found in the ears, nose and throat of mammals, is uniquely packed with fat-filled cells called “lipochondrocytes” that provide super-stable internal support, enabling the tissue to remain soft and springy—similar to bubbled packaging material.

The study, published in the journal Science, describes how lipocartilage cells create and maintain their own lipid reservoirs, remaining constant in size. Unlike ordinary adipocyte fat cells, lipochondrocytes never shrink or expand in response to food availability.

A new era in genetic engineering: Researchers present single tool with multiple gene editing functions

Influential inventions often combine existing tools in new ways. The iPhone, for instance, amalgamated the telephone, web browser and camera, among many other devices.

The same is now possible in . Rather than employ separate tools for editing genes and regulating their expression, these distinct goals can now be combined into a single tool that can simultaneously and independently address different genetic diseases in the same cell.

In a new paper in Nature Communications, researchers in the Center for Precision Engineering for Health (CPE4H) at the University of Pennsylvania School of Engineering and Applied Science (Penn Engineering) describe minimal versatile genetic perturbation technology (mvGPT).

Polymer-based network gives artificial cells a life-like cytoskeleton

Just like your body has a skeleton, every cell in your body has a skeleton—a cytoskeleton to be precise. This provides cells with mechanical resilience, as well as assisting with cell division. To understand how real cells work, e.g. for drug and disease research, researchers create artificial cells in the laboratory.

However, many artificial cells to date cannot be used to study how cells respond to forces as they don’t have a . TU/e researchers have designed a polymer-based network for artificial cells that mimics a real cytoskeleton, thus making it possible to study with greater accuracy in artificial cells how cells respond to forces.

The research is published in the journal Nature Chemistry.

Detecting disease with a single molecule: Nanopore-based sensors could transform diagnostics

UC Riverside scientists have developed a nanopore-based tool that could help diagnose illnesses much faster and with greater precision than current tests allow, by capturing signals from individual molecules.

Since the molecules scientists want to detect—generally certain DNA or protein molecules—are roughly one-billionth of a meter wide, the they produce are very small and require specialized detection instruments.

“Right now, you need millions of molecules to detect diseases. We’re showing that it’s possible to get useful data from just a ,” said Kevin Freedman, assistant professor of bioengineering at UCR and lead author of a paper about the tool appearing in Nature Nanotechnology. “This level of sensitivity could make a real difference in disease diagnostics.”

“WWI Fighter Plane Hack” Inspires Breakthrough in Cancer Treatment

Researchers at the University of Massachusetts Amherst have developed an innovative technology inspired by the synchronization mechanism of WWI fighter aircraft, which coordinated machine gun fire with propeller movement. This breakthrough allows precise, real-time control of the pH in a cell’s environment to influence its behavior. Detailed in Nano Letters, the study opens exciting possibilities for developing new cancer and heart disease therapies and advancing the field of tissue engineering.

“Every cell is responsive to pH,” explains Jinglei Ping, associate professor of mechanical and industrial engineering at UMass Amherst and corresponding author of the study. “The behavior and functions of cells are impacted heavily by pH. Some cells lose viability when the pH has a certain level and for some cells, the pH can change their physiological properties.” Previous work has demonstrated that changes of pH as small as 0.1 pH units can have physiologically significant effects on cells.