Archive for the ‘bioengineering’ category: Page 19

May 13, 2023

Resurrecting a 2.6 billion-year-old ancient CRISPR system

Posted by in categories: bioengineering, biotech/medical, employment, food

Incapable of replicating on their own, viruses must hijack other organisms, like bacteria, to continue their existence. Little wonder, then, that bacteria had to develop ways to fight back.

Among them is CRISPR, a kind of an immune system that keeps DNA records of previous infections and then uses a protein called Cas to attack viruses that show up again. When Cas reaches a targeted virus, it cleaves the viral DNA, protecting the bacteria from infection.

Researchers have harnessed that targeted, DNA-snipping ability as a gene editing tool for all kinds of organisms. CRISPR can now be found in a variety of fields doing a variety of jobs, from helping to fight sickle cell and high cholesterol in humans to gene editing animals and crops. It’s proven to be an amazingly versatile tool.

May 10, 2023

Fake blood pumps life into this robotic fish

Posted by in categories: bioengineering, biotech/medical, robotics/AI

Researchers have engineered a robotic lionfish with synthetic arteries, similar to those found in a human’s circulatory system. The fish “blood” that runs through it serves as both the robot’s power source and controls its movement. The findings, published Wednesday in Nature, may propel the new wave of soft robots, in which inventors seek to improve lifelike automated machines for human connection.

Synthetic blood vessels in a new robotic fish could improve the technology needed to make lifelike robots run longer.

May 8, 2023

Researchers engineer solution to extend cellular lifespan and slow aging

Posted by in categories: bioengineering, biotech/medical, genetics, life extension

Human lifespan is intricately connected to the aging process of individual cells, and this means that scientists have spent decades trying to unravel the mysteries of cellular aging and exploring methods to slow down the ticking of the aging clock.

Longevity. Technology: In 2020, a group of researchers from the University of California San Diego identified two distinct mechanisms of cellular aging and genetically manipulated them to extend cell lifespan [1]. Now, their research has progressed to employ synthetic biology and gene circuits to delay the deterioration associated with cellular aging [2]. The team’s innovative approach could revolutionize scientific methods of aging prevention and contribute to reprogramming aging pathways in various human cell types.

Publishing in Science, the researchers describe how cells in yeast, plants, animals and humans all contain gene regulatory circuits responsible for several physiological functions, including aging. These gene circuits, akin to electric circuits controlling household devices, can operate in different ways, and the UC San Diego team discovered that cells don’t necessarily age the same way – it all depends on their genetic material and environment. The researchers found that cells can age either through DNA stability decline or mitochondrial decline.

May 5, 2023

A new nondestructive method for assessing bioengineered artificial tissues

Posted by in categories: bioengineering, biotech/medical, health

Engineering organs to replace damaged hearts or kidneys in the human body may seem like something out of a sci-fi movie, but the building blocks for this technology are already in place. In the burgeoning field of tissue engineering, live cells grow in artificial scaffolds to form biological tissue. But to evaluate how successfully the cells develop into tissue, researchers need a reliable method to monitor the cells as they move and multiply.

Now, scientists at the National Institute of Standards and Technology (NIST), the U.S Food and Drug Administration (FDA) and the National Institutes of Health (NIH) have developed a noninvasive method to count the in a three-dimensional (3D) . The real-time technique images millimeter-scale regions to assess the viability of the cells and how the cells are distributed within the scaffold—an important capability for researchers who manufacture complex biological tissues from simple materials such as living cells.

Their findings have been published in the Journal of Biomedical Materials Research Part A.

May 5, 2023

A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence Medicine

Posted by in categories: bioengineering, biotech/medical

The WHO says covid is no longer an emergency, yet does not say where covid originated from. No one knows. What I know is that covid is a cute name for SARS/Coronavirus. Something made in a lab at UNC Chapel Hill with Ralph Baric and his collegue from Wuhan China which he shared his gain of function research with. However the Nature article published in 2015 has this disclaimer, yet there is no animal origin after more than 3 years. So what do we believe?

“30 March 2020 Editors’ note, March 2020: We are aware that this article is being used as the basis for unverified theories that the novel coronavirus causing COVID-19 was engineered. There is no evidence that this is true; scientists believe that an animal is the most likely source of the coronavirus.”

The results indicate that group 2b viruses encoding the SHC014 spike in a wild-type backbone can efficiently use multiple orthologs of the SARS receptor human angiotensin converting enzyme II (ACE2), replicate efficiently in primary human airway cells and achieve in vitro titers equivalent to epidemic strains of SARS-CoV. ACE2 🤔

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May 3, 2023

Mind-reading machines are here: is it time to worry?

Posted by in categories: bioengineering, ethics, law, neuroscience

Neurotech will bring many amazing positive changes to the world, such as treating ailments like blindness, depression, and epilepsy, giving us superhuman sensory capabilities that allow us to understand the world in new ways, accelerating our ability to cognitively process information, and more. But in an increasingly connected society, neuroprivacy will represent a crucial concern of the future. We must carefully devise legal protections against misuse of “mind reading” technology as well as heavily invest in “neurocybersecurity” R&D to prevent violation of people’s inner thoughts and feelings by authorities and malignant hackers. We can capitalize on the advantages, but we must do establish safety mechanisms as these technologies mature. #neurotechnology #neuroscience #neurotech #computationalbiology #future #brain

Determining how the brain creates meaning from language is enormously difficult, says Francisco Pereira, a neuroscientist at the US National Institute of Mental Health in Bethesda, Maryland. “It’s impressive to see someone pull it off.”‘

‘Wake-up call’

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May 3, 2023

This solar-powered motorhome was designed by students

Posted by in categories: bioengineering, computing, solar power, sustainability, transportation

A solar-powered motorhome, shaped like a huge elongated teardrop, silently rolled into Madrid on Friday as part of a month-long journey from the Netherlands to southern Spain to highlight more sustainable modes of transport.

Engineering students at the Technical University of Eindhoven in the Netherlands created the blue and white vehicle, named Stella Vita – Latin for “star” and “life” – to inspire car makers and politicians to accelerate the transition toward green energy.

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May 2, 2023

Researchers develop gene-edited stem cells to reduce arrhythmias in heart attack patients

Posted by in categories: bioengineering, biotech/medical, genetics

In a recent study published in the journal Cell Stem Cell, researchers hypothesized that pacemaker-like activity of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) resulted in engraftment arrhythmias (EAs), which hampers the clinical use of cell-based therapy using hPSC-CMs for treatment of myocardial infarction (MI).

Study: Gene editing to prevent ventricular arrhythmias associated with cardiomyocyte cell therapy. Image Credit: FrentaN / Shutterstock.

May 1, 2023

Lung Nanoparticles Could Treat Rare Diseases

Posted by in categories: bioengineering, biotech/medical, genetics, nanotechnology

Researchers designed nanoparticles that can deliver mRNA gene editing solutions directly to the lungs to address rare genetic diseases.

May 1, 2023

2023 MIT Club of Boston BioSummit

Posted by in categories: bioengineering, biotech/medical, food, life extension

It was an honor to speak at MIT’s Broad Institute about some of my past and present synthetic biology research on redesigning bacteria and viruses to act as delivery systems for biomedicine! Video recording is now available! Here is a link which should take you to 1:40:18 when my talk starts:[ ]. My talk was part of the inaugural MIT Biosummit (, a forward-looking conference which this year focused on tackling challenges at the interface of climate change and health sciences. #futureofmedicine #future #biotech #mit Thank you Ryan Robinson for helping to organize this conference and for giving your own excellent talk!

Recording of the MIT Club of Boston 2023 BioSummit: Human Health 2050 held at the Broad Institute on April 27, 2023. Note: Although the video is almost 6 hours long, you can rapidly navigate and skip to a particular speaker or session by scrubbing along the video timeline (in Chrome or Edge) or using the time markers listed below in blue (in all browsers). You can also use chapter browsing in the YouTube app on platforms where it is available.

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