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Yuri Deigin | Brain Rejuvenation by Partial Reprogramming @ Vision Weekend 2025, Puerto Rico

*This video was recorded at Foresight’s Vision Weekend 2025 in Puerto Rico*
https://foresight.org/vw2025pr/

Our Vision Weekends are the annual festivals of Foresight Institute. Held in two countries, over two weekends, you are invited to burst your tech silos and plan for flourishing long-term futures. This playlist captures the magic of our Puerto Rico edition, held February 21–23, 2025, in the heart of Old San Juan. Come for the ideas: join the conference, unconference, mentorship hours, curated 1-1s, tech demos, biohacking sessions, prize awards, and much more. Stay for fun with new friends: join the satellite gatherings, solarpunk future salsa night, beach picnic, and surprise island adventures. This year’s main conference track is dedicated to “Paths to Progress”; meaning you will hear 20+ invited presentations from Foresight’s core community highlighting paths to progress in the following areas: Existential Hope Futures, Longevity, Rejuvenation, Cryonics, Neurotech, BCIs & WBEs, Cryptography, Security & AI, Fusion, Energy, Space, and Funding, Innovation, Progress.
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*About The Foresight Institute*

The Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1986 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support. From molecular nanotechnology, to brain-computer interfaces, space exploration, cryptocommerce, and AI, Foresight gathers leading minds to advance research and accelerate progress toward flourishing futures.

*We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page:* https://foresight.org/donate/

*Visit* https://foresight.org, *subscribe to our channel for more videos or join us here:*

Niccolo Zanichelli | The State of Brain Emulation in 2025 @ Vision Weekend 2025, Puerto Rico

*This video was recorded at Foresight’s Vision Weekend 2025 in Puerto Rico*
https://foresight.org/vw2025pr/

Our Vision Weekends are the annual festivals of Foresight Institute. Held in two countries, over two weekends, you are invited to burst your tech silos and plan for flourishing long-term futures. This playlist captures the magic of our Puerto Rico edition, held February 21–23, 2025, in the heart of Old San Juan. Come for the ideas: join the conference, unconference, mentorship hours, curated 1-1s, tech demos, biohacking sessions, prize awards, and much more. Stay for fun with new friends: join the satellite gatherings, solarpunk future salsa night, beach picnic, and surprise island adventures. This year’s main conference track is dedicated to “Paths to Progress”; meaning you will hear 20+ invited presentations from Foresight’s core community highlighting paths to progress in the following areas: Existential Hope Futures, Longevity, Rejuvenation, Cryonics, Neurotech, BCIs & WBEs, Cryptography, Security & AI, Fusion, Energy, Space, and Funding, Innovation, Progress.
══════════════════════════════════════

*About The Foresight Institute*

The Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1986 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support. From molecular nanotechnology, to brain-computer interfaces, space exploration, cryptocommerce, and AI, Foresight gathers leading minds to advance research and accelerate progress toward flourishing futures.

*We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page:* https://foresight.org/donate/

*Visit* https://foresight.org, *subscribe to our channel for more videos or join us here:*

Cooler, faster, better: Crystal waves enable ultrafast heat transfer for cooler electronics

Imagine if phones never got hot no matter how many apps were running. Picture a future where supercomputers use less energy, electric cars charge faster, and life-saving medical devices stay cooler and last longer.

In a study published in Nature Materials, a team of engineers at the University of Virginia and their collaborators revealed a radical new way to move heat, faster than ever before. Using a special kind of crystal called hexagonal boron nitride (hBN), they found a way to move heat like a beam of light, sidestepping the usual bottlenecks that make electronics overheat.

“We’re rethinking how we handle heat,” said Patrick Hopkins, professor of mechanical and aerospace engineering and Whitney Stone Professor of Engineering at UVA. “Instead of letting it slowly trickle away, we’re directing it.”

Master switch gene can turn immune cells into cancer eradicators

To grow, cancer tumors must hijack the immune system for their needs. One of the main tricks that most tumors use is to manipulate a type of immune cell called a macrophage, causing it to protect the tumor from the rest of the immune system, recruit blood vessels and help the cancer spread to other tissues.

Now researchers in Prof. Ido Amit’s lab at the Weizmann Institute of Science have used state-of-the-art gene editing and single-cell and AI technologies to identify a master switch that turns macrophages into cancer helpers.

Based on this discovery, the team developed a new therapy that was shown to be effective in mice with bladder tumors, one of the most common types of cancer in humans and one for which only limited therapeutic innovations are currently available. The discovery is presented in a paper published in the journal Cancer Cell.

Vaibhav Sisinty (@vaibhavsisinty) • Instagram reel

17K likes, — vaibhavsisinty on March 27, 2025: “Your Future Kids Might Be Genetically Engineered🤯… [genetic engineering, CRISPR, designer babies, IVF, in vitro gametogenesis, gene editing, human evolution, bioethics, futuristic science, AI in healthcare, medical advancements, artificial reproduction, skin cell gametes, future tech, DNA modification, biotechnology]”

Smart delivery tech boosts CRISPR efficiency, restores vision in mice

A research team from Helmholtz Munich and the Technical University of Munich has developed an advanced delivery system that transports gene-editing tools based on the CRISPR/Cas9 gene-editing system into living cells with significantly greater efficiency than before. Their technology, ENVLPE, uses engineered non-infectious virus-like particles to precisely correct defective genes—demonstrated successfully in living mouse models that are blind due to a mutation.

This system also holds promise for advancing by enabling precise genetic manipulation of engineered , making them more universally compatible and thus more accessible for a larger group of cancer patients.

The work is published in the journal Cell.

Nanoplastics in soil: How soil type and pH influence mobility

Plastics are everywhere—from packaging and textiles to electronics and medical devices. As plastic waste breaks down, it releases microscopic particles that can penetrate our ecosystems, hinder plant growth, and potentially transfer harmful pollutants to organisms, including humans. Therefore, these plastic particles are a potential threat to the ecosystem, especially in their nanoparticulate form (1–100 nm diameter), which can penetrate the environment through different routes, including the soil beneath our feet.

With this in mind, a team of researchers from Japan set out to study the migration behavior of nanoplastics in different soil types. The study was led by Kyouhei Tsuchida, a Ph.D. student from the National Institute of Advanced Industrial Science and Technology (AIST) and Waseda University, Japan, with fellow students Yukari Imoto, Takeshi Saito, and Junko Hara also from AIST, and Professor Yoshishige Kawabe from the Department of Resources and Environmental Engineering, Waseda University. This study was published online in the journal Science of the Total Environment on April 4, 2025.

The researchers focused on the adsorption of the nanoplastics on soil and the aggregation characteristics of both the nanoplastics and soil particles under varying pH conditions. “The aggregation properties of nanoplastics and their adsorption onto soil particle surfaces are known to affect their migration in soil,” notes Tsuchida. “We conducted experiments to analyze these traits to get a better understanding of the migration of nanoplastics.”

Scientists discover that fruit fly larvae can sense electric fields

While it may be an unfamiliar sensation to humans, electroreception is relatively commonplace in the animal kingdom. Sharks, bees and even the platypus all share this ability to detect electric fields in their environment.

Scientists at UC Santa Barbara have just added to that list. A team of researchers led by Matthieu Louis found that fruit fly larvae can sense electric fields and navigate toward the negative electric potential using a small set of sensory neurons in their head.

The findings, published in Current Biology, present an immense opportunity. Fruit flies are arguably the most commonly used experimental animals, the basis for studies in fields as disparate as genetics, neurobiology and aging. Uncovering electroreception in fruit flies opens new avenues of research into the basis of this sense and could even lead to new techniques in bioengineering.

Green recipe: Engineered yeast boosts D-lactic acid production

Constructed strain achieves record-high yield from methanol, advancing ecofriendly biomanufacturing. Researchers from Osaka Metropolitan University have discovered the ideal genetic “recipe” to turn yeast into a tiny yet powerful eco-friendly factory that converts methanol into D-lactic acid, a key compound used in biodegradable plastics and pharmaceuticals.

This approach could help reduce reliance on petroleum-based processes and contribute to more sustainable chemical production.

Lactic acid is widely used in food, cosmetics, pharmaceuticals and bioplastics.

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