Archive for the ‘bioengineering’ category: Page 13

Jul 9, 2019

Neuroscience and artificial intelligence can help improve each other

Posted by in categories: bioengineering, biological, information science, neuroscience, robotics/AI

Despite their names, artificial intelligence technologies and their component systems, such as artificial neural networks, don’t have much to do with real brain science. I’m a professor of bioengineering and neurosciences interested in understanding how the brain works as a system – and how we can use that knowledge to design and engineer new machine learning models.

In recent decades, brain researchers have learned a huge amount about the physical connections in the brain and about how the nervous system routes information and processes it. But there is still a vast amount yet to be discovered.

At the same time, computer algorithms, software and hardware advances have brought machine learning to previously unimagined levels of achievement. I and other researchers in the field, including a number of its leaders, have a growing sense that finding out more about how the brain processes information could help programmers translate the concepts of thinking from the wet and squishy world of biology into all-new forms of machine learning in the digital world.

Jul 8, 2019

This design exchange consortium could accelerate the synthetic biology industry

Posted by in categories: bioengineering, biological, finance

Introducing the SBOL Industrial Consortium

To this end, a group of companies are now launching a pre-competitive consortium to support the industrial application of these technologies. The SBOL Industrial Consortium is a non-profit organization supporting innovation, dissemination, and integration of SBOL standards, tools and practices for practical applications in an industrial environment. The six founding companies of the consortium are Raytheon BBN Technologies, Amyris, Doulix, IDT, Shipyard Toolchains, TeselaGen, and Zymergen, representing a diverse set of interests and business models across the synthetic biology community.

The SBOL Industrial Consortium will facilitate industry-focused development of representational technologies in several ways. The consortium will help coordinate development of standards and tools, both with the academic community and from member to member, in order to ensure that the SBOL standards are well-tuned to support the specific industrial needs of the members of the consortium. Financial support will also be provided by the consortium for selected projects and activities, and for key pieces of community infrastructure.

Jul 5, 2019

Gene Editing Startups Fabricate Industrial-Grade CRISPR Tools

Posted by in categories: bioengineering, biotech/medical

The old DIY CRISPR tickles some, but it underwhelms others, namely, the developers of commercial applications. They prefer the new CRISPR—scalable, reliable, and deliverable.

Jul 5, 2019

Dr. Steffanie Strathdee PhD. — UCSD Center for Innovative Phage Applications and Therapeutics (IPATH) — ideaXme — Ira Pastor

Posted by in categories: aging, bioengineering, biotech/medical, counterterrorism, defense, disruptive technology, existential risks, genetics, health, life extension

Jul 3, 2019

Bacteria engineered as Trojan horse for cancer immunotherapy

Posted by in categories: bioengineering, biotech/medical, genetics

The emerging field of synthetic biology—designing new biological components and systems—is revolutionizing medicine. Through the genetic programming of living cells, researchers are creating engineered systems that intelligently sense and respond to diverse environments, leading to more specific and effective solutions in comparison to current molecular-based therapeutics.

At the same time, —using the body’s immune defenses to fight cancer—has transformed over the past decade, but only a handful of have responded, and often results in significant side effects. Designing therapies that can induce a potent, anti– immune response within a solid tumor without triggering systemic toxicity has posed a significant challenge.

Researchers at Columbia Engineering and Columbia University Irving Medical Center (CUIMC) announced today that they are addressing this challenge by engineering a strain of non– that can colonize solid tumors in mice and safely deliver potent immunotherapies, acting as a Trojan Horse that treats tumors from within. The therapy led not only to complete tumor regression in a mouse model of lymphoma, but also significant control of distant, uninjected tumor lesions. Their findings are published today in Nature Medicine.

Jul 2, 2019

Scissors get stuck—another way bacteria use CRISPR/Cas9

Posted by in categories: bioengineering, biotech/medical

In biotech these days, CRISPR/Cas9 is a hot topic, because of its utility as a precise gene editing tool. Before humans repurposed it, CRISPR/Cas9 was a sort of internal immune system bacteria use to defend themselves against phages, or viruses that infect bacteria, by slicing up the phages’ DNA.

Scientists at Emory University School of Medicine and the Max Planck Unit for the Science of Pathogens have found that the “scissors” component of CRISPR/Cas9 sometimes gets stuck.

Cas9, an enzyme that cuts DNA, can also block without doing any cutting. In the pathogenic bacterium Francisella novicida, Cas9 regulates that need to be shut off for the bacteria to cause disease.

Jul 2, 2019

Have mice really been cured of HIV using CRISPR gene editing?

Posted by in categories: bioengineering, biotech/medical

Some mice receiving a therapy that includes CRISPR gene editing appear to have been cured of HIV, but safety concerns must be overcome before human trials.

Jul 2, 2019

U.S. Army Making Synthetic Biology a Priority

Posted by in categories: bioengineering, biotech/medical, military

New thermal cloaking, insect proof uniforms are on the horizon, if the U.S. can get out in front of China.

The U.S. Army’s new Futures Command is accelerating research into synthetic biotechnology to help the military develop next-generation living camouflage and other never-before-seen organisms and materials.

Dimitra Stratis-Cullum, who is overseeing the research in synthetic biology for the U.S. Army Research Laboratory’s Combat Capabilities Development Command, detailed the effort on Thursday at the fourth annual Defense One Tech Summit.

Jul 2, 2019

First life with ‘alien’ DNA

Posted by in categories: bioengineering, biotech/medical, genetics

Circa 2014

An engineered bacterium is able to copy DNA that contains unnatural genetic letters.

Jul 1, 2019

Anti-Aging Approaches

Posted by in categories: bioengineering, biotech/medical, life extension

Sirtuins can be activated by a lack of amino acids or of sugar, or through an increase in NAD. — David Sinclair If you have not heard of #davidsinclair then it is time you have. he is at the forefront of anti aging research and one of my heroes. While we wait for the miracle pills there are alot of thing we can do to help us age better already. #biohacking #biohacker

Can a single molecule extend lifespan?

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