Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: bioengineering – Page 13

Oxford University researchers have made a significant step toward realizing a form of “biological electricity” that could be used in a variety of bioengineering and biomedical applications, including communication with living human cells. The work was published on 28 November in the journal Science.

Iontronic devices are one of the most rapidly-growing and exciting areas in biochemical engineering. Instead of using electricity, these mimic the by transmitting information via ions (charged particles), including sodium, potassium, and .

Ultimately, iontronic devices could enable biocompatible, energy-efficient, and highly precise signaling systems, including for drug-delivery.

Read more | >

Bill Faloon discusses advancements in age reversal therapies and their transition from research to clinical application, emphasizing the potential for delaying and reversing biological aging. He highlights advancements in age reversal, discussing therapies like young plasma, gene editing, yamanaka factors and exosome treatments, emphasizing their potential to reverse aging, improve health, and extend lifespan.

Credits to : Age Reversal Network https://age-reversal.net/

Please note that the links below are affiliate links, so we receive a small commission when you purchase a product through the links. Thank you for your support!
=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=
🔖Stem Cells Enhancers : STEMREGEN 15% OFF CODE: REVERSE : https://stemregen.co/reverse.

☑ProHealth, DoNotAge, Renue☑ All Products Discount Coupon CODE: REVERSE
🌏ProHealth Longevity 15% OFF All Products \& Upto 45% Subscription https://prohealth.pxf.io/REVERSEAGING
Calcium AKG 500mg Caps https://prohealth.pxf.io/CaAKG
Full Spectrum Apigenin https://prohealth.pxf.io/apigenin.
Longevity Collagen https://prohealth.pxf.io/LongevityCol…
Berberine Pro 600 mg Caps https://prohealth.pxf.io/Berberine.
Astaxanthin 12mg https://prohealth.pxf.io/astaxanthin.

🧬DoNotAge 10% OFF https://donotage.org/products?affilia…
Ca-AKG https://tinyurl.com/2azxfx83
Pure Spermidine http://tinyurl.com/yc2xbp65 Pure Hyaluronic Acid http://tinyurl.com/3kt8jmxj.

🔶 Nuchido https://www.nuchido.com/REVERSEAGING FIRST ORDER 20% OFF code : REVERSEAGING20.

Continue reading “How to REVERSE AGING: The Latest Scientific Advances” | >

A tiny, four-fingered “hand” folded from a single piece of DNA can pick up the virus that causes COVID-19 for highly sensitive rapid detection and can even block viral particles from entering cells to infect them, University of Illinois Urbana-Champaign researchers report. Dubbed the NanoGripper, the nanorobotic hand also could be programmed to interact with other viruses or to recognize cell surface markers for targeted drug delivery, such as for cancer treatment.

Led by Xing Wang, a professor of bioengineering and of chemistry at the U. of I., the researchers describe their advance in the journal Science Robotics.

Inspired by the gripping power of the human hand and bird claws, the researchers designed the NanoGripper with four bendable fingers and a palm, all in one nanostructure folded from a single piece of DNA. Each finger has three joints, like a human finger, and the angle and degree of bending are determined by the design on the DNA scaffold.

Read more | >

Advance paves the way for broad applications in medicine and biotech. Researchers from the UCLA Samueli School of Engineering and the University of Rome Tor Vergata in Italy have developed synthetic genes that function like the genes in living cells.

The artificial genes can build intracellular structures through a cascading sequence that builds self-assembling structures piece by piece. The approach is similar to building furniture with modular units, much like those found at IKEA. Using the same parts, one can build many different things and it’s easy to take the set apart and reconstruct the parts for something else. The discovery offers a path toward using a suite of simple building blocks that can be programmed to make complex biomolecular materials, such as nanoscale tubes from DNA tiles. The same components can also be programmed to break up the design for different materials.

The research study was recently published in Nature Communications and led by Elisa Franco, a professor of mechanical and aerospace engineering and bioengineering at UCLA Samueli. Daniela Sorrentino, a postdoctoral scholar in Franco’s Dynamic Nucleic Acid Systems lab, is the study’s first author.

Read more | >

This is the first symposium of Xapiens at MIT — “The Future of Homo Sapiens”

The future of our species will be majorly influenced by the technical advancements and ethical paradigm shifts over the next several decades. Artificial intelligence, neural enhancement, gene editing, solutions for aging and interplanetary travel, and other emerging technologies are bringing sci-fi’s greatest ideas to reality.

Sponsored by the MIT media lab and the MIT mcgovern institute of brain research.

Full Agenda:

- Openings remarks from Joe Paradiso — https://youtu.be/9bG40ySgE8I
A.W Dreyfoos Professor and Associate Academic Head of Media Arts and Sciences at MIT Director of the Responsive Environments Group.

- Pattie Maes — https://youtu.be/b-16PW9RvJc.

Continue reading “Ed Boyden — The Future of Humanity | Xapiens Symposium” | >

In a new work, a team from the University of Pennsylvania tracked the impact of alcohol consumption from the age of 20 on brain health and came to disappointing conclusions.

UNIVERSITY PARK, Pa. — Binge drinking in early adults can lead to long-lasting and potentially permanent dysregulation in the brain, according to a new study in mice, led by researchers at Penn State. They found that neurons, cells that transmit information in the brain via electrical and chemical signals, showed changes following binge drinking were similar in many ways to those seen with cognitive decline.

These findings, published in the journal Neurobiology of Aging, reveal that binge drinking early in life may have lasting impacts that are predictive of future health issues, like Alzheimer’s disease and related dementias, the researchers said. The work could inform the development of therapeutics to help combat these changes — particularly in aging populations who may have given up alcohol decades earlier, according to Nikki Crowley, director of the Penn State Neuroscience Institute at University Park, Huck Early Career Chair in Neurobiology and Neural Engineering, assistant professor of biology in the Eberly College of Science, and the leader of the research team.

“We know from previous studies that there are immediate effects of binge drinking on the brain, but we didn’t have any sense of if these changes were long-lasting, or reversible over time,” said Crowley, who is also an assistant professor of biomedical engineering and of pharmacology. “We were interested in understanding if binge drinking during early adulthood may have lasting consequences that are not revealed until later in life — even if drinking had stopped for a very long period of time. This allows us to consider the effects of alcohol on an individual’s holistic health, in terms of their entire life history.”

Read more | >

This capsule…

Inspired by the way that squids use jets to propel themselves through the ocean and shoot ink clouds, researchers from MIT and Novo Nordisk have developed an ingestible capsule that releases a burst of drugs directly into the wall of the stomach or other organs of the digestive tract.

This capsule could offer an alternative way to deliver drugs that normally have to be injected, such as insulin and other large proteins, including antibodies. This needle-free strategy could also be used to deliver RNA, either as a vaccine or a therapeutic molecule to treat diabetes, obesity, and other metabolic disorders.

“One of the longstanding challenges that we’ve been exploring is the development of systems that enable the oral delivery of macromolecules that usually require an injection to be administered. This work represents one of the next major advances in that progression,” says Giovanni Traverso, director of the Laboratory for Translational Engineering and an associate professor of mechanical engineering at MIT, a gastroenterologist at Brigham and Women’s Hospital, an associate member of the Broad Institute, and the senior author of the study.

Read more | >

Communication and coordination among different cells are fundamental aspects that regulate many functions in our body. This process, known as paracrine signaling, involves the release of signaling molecules by a cell into its extracellular matrix (ECM) or surroundings to communicate changes in its cellular processes or the local environment. These signaling molecules are then detected by neighboring cells, leading to various cellular responses.

For instance, during cell/tissue injury, the paracrine signaling process releases that signal nearby stem cells to assist in tissue repair in the form of scar tissue formation or blood clotting. Similar processes occur in the regulation of other vital functions, such as digestion, respiration, and reproduction. Additionally, paracrine signals influence the expression and activity of enzymes involved in drug metabolism and play a role in drug–drug interactions.

The signaling molecules, which may contain proteins and , are transported within tiny vesicles called exosomes. These vesicles serve as valuable biomarkers for various diseases and can even be engineered to carry drugs, making them a highly effective targeted drug delivery system. Notably, the hormone oxytocin and the neurotransmitter dopamine are paracrine messengers.

Read more | >