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The story of humanity is progress, from the origins of humanity with slow disjointed progress to the agricultural revolution with linear progress and furthermore to the industrial revolution with exponential almost unfathomable progress.

This accelerating rate of change of progress is due to the compounding effect of technology, in which it enables countless more from 3D printing, autonomous vehicles, blockchain, batteries, remote surgeries, virtual and augmented reality, robotics – the list can go on and on. These devices in turn will lead to mass changes in society from energy generation, monetary systems, space colonization, automation and much more!

This trajectory of progress is now leading us into a time period that is, “characterized by a fusion of technologies that is blurring the lines between the physical, digital and biological spheres”, called by many the technological revolution or the 4th industrial revolution — in which everything will change, from the underlying structure and fundamental institutions of society to how we live our day-to-day lives.

00:00 Intro.

In America, at least 17 people a day die waiting for an organ transplant. But instead of waiting for a donor to die, what if we could someday grow our own organs?

Last week, six years after NASA announced its Vascular Tissue Challenge, a competition designed to accelerate research that could someday lead to artificial organs, the agency named two winning teams. The challenge required teams to create thick, vascularized human organ tissue that could survive for 30 days.

The two teams, named Winston and WFIRM, both from the Wake Forest Institute for Regenerative Medicine, used different 3D-printing techniques to create lab-grown liver tissue that would satisfy all of NASA’s requirements and maintain their function.

“We did take two different approaches because when you look at tissues and vascularity, you look at the body doing two main things,” says Anthony Atala, team leader for WFIRM and director of the institute.

The two approaches differ in the way vascularization—how blood vessels form inside the body—is achieved. One used tubular structures and the other spongy tissue structures to help deliver cell nutrients and remove waste. According to Atala, the challenge represented a hallmark for bioengineering because the liver, the largest internal organ in the body, is one of the most complex tissues to replicate due to the high number of functions it performs.


Researchers used 3D-printing to create human liver tissue that could soon be tested on the International Space Station.

Volumetric 3D bioprinter manufacturer and EPFL spin-out Readily3D has taken the first step towards developing a 3D printed living model of the human pancreas for testing diabetes medicines.

Readily3D’s novel technology is being deployed within the EU-funded Enlight project and is reportedly capable of 3D printing a biological tissue containing human stem cells in just 30 seconds.

As the project’s official bioprinter manufacturer, the company has adapted its proprietary contactless tomographic illumination technology to suit the specific needs of pancreatic tissue structures.

Circa 2020


The FRESH technique of 3D bioprinting was invented in Feinberg’s lab to fill an unfilled demand for 3D printed soft polymers, which lack the rigidity to stand unsupported as in a normal print. FRESH 3D printing uses a needle to inject bioink into a bath of soft hydrogel, which supports the object as it prints. Once finished, a simple application of heat causes the hydrogel to melt away, leaving only the 3D bioprinted object.

While Feinberg, a professor of biomedical engineering and materials science and engineering, has proven both the versatility and the fidelity of the FRESH technique, the major obstacle to achieving this milestone was printing a human heart at full scale. This necessitated the building of a new 3D printer custom made to hold a gel support bath large enough to print at the desired size, as well as minor software changes to maintain the speed and fidelity of the print.

Scientists have successfully grown liver tissue capable of functioning for 30 days in the lab as part of NASA’s Vascular Tissue Challenge.

In 2016, NASA put forth this competition to find teams that could “create thick, vascularized human organ tissue in an in-vitro environment to advance research and benefit medicine on long-duration missions and on Earth,” according to an agency challenge description. Today (June 9), the agency announced not one, but two winners of the challenge.

Article I just wrote about how going to Mars is actually good for protecting life on Earth, too.


People often lump going to Mars or the Moon into a this/that fight when it comes to bettering the life of the Earth and its inhabitants. But, it’s not that simple.

The technology we master in the pursuit of space colonization (starti n g at the Moon and Mars / space stations) will serve to advance that on Earth. The things we learn will help provide a guide for what to do on this future planet, and not just life beyond it. Sure, in-situ resource utilization/production will generate rocket fuel on extraterrestrial bodies. But, things like the NASA Kilopower nuclear reactor can lay the groundwork for alternative energies deployed on Earth at scale. I imagine thorium reactors will follow suit while we still try to deploy fusion at a consumer scale and not just a research basis.

That’s just energy. Now picture 3D printing habitat development and how that can impact production of low-cost housing on Earth and construction projects that can have shapes previously thought impossible or too-high a cost that are more efficient and allow for artists to sculpt new buildings like a sculpture rather than a boring block.

3D printed food is no longer the domain of sci-fi fantasy. It’s here and it’s real: but is it really a big deal, or is it just a passing fad?


In science fiction television shows and movies such as those in the Star Trek universe, the food synthesizers or replicators were electronic devices that took base elements and transformed them into any type of food that was desired. This seemingly miraculous device could only exist in the world of science fiction — at least for now. However, thanks to the advances in 3D printing, it is now possible to create food that mimics the taste, shape, and color of familiar dishes.

Over the past few years, 3D printers have become more commonplace in commercial industries and are used to create all types of items that range from small models and jewelry up to large construction items used to create buildings. But what about 3D printed foods? Is it the future of gastronomy, or just a quirky fad?

Essentially, 3D printing food works by the same principles of regular additive manufacturing, except that the material being extruded is edible. Thanks to the advances in 3D digital design technology and the incorporation of the right materials, it is now possible to create the shapes, tastes, textures, and overall forms of food that are not possible to do by hand. The result is food that is recognizable, edible, and can be created using the 3D printing.

3D printing, also called additive manufacturing, has become widespread in recent years. By building successive layers of raw material such as metals, plastics, and ceramics, it has the key advantage of being able to produce very complex shapes or geometries that would be nearly impossible to construct through more traditional methods such as carving, grinding, or molding.

The technology offers huge potential in the health care sector. For example, doctors can use it to make products to match a patient’s anatomy: a radiologist could create an exact replica of a patient’s spine to help plan surgery; a dentist could scan a patient’s broken tooth to make a perfectly fitting crown reproduction. But what if we took a step further and apply 3D printing techniques to neuroscience?

Stems cells are essentially the body’s raw materials; they are pluripotent elements from which all other cells with specialized functions are generated. The development of methods to isolate and generate human stem cells, has excited many with the promise of improved human cell function understanding, ultimately utilizing them for regeneration in disease and trauma. However, the traditional two-dimensional growth of derived neurones–using flat petri dishes–presents itself as a major confounding factor as it does not adequately mimic in vivo three-dimensional interactions, nor the myriad developmental cues present in real living organisms.

To address this limitation in current neuronal culturing approaches, the FET funded MESO-BRAIN project, led by Aston University, proposed a highly ambitious interdisciplinary enterprise to construct truly 3D networks that not only displayed in vivo activity patterns of neural cultures but also allowed for precise interaction with these cultures. This allows the activity of individual elements to be readily monitored and controlled through electrical stimulation.

The ability to develop human-induced pluripotent stem cell derived neural networks upon a defined and reproducible 3D scaffold that can emulate brain activity, allows for a comprehensive and detailed investigation of neural network development.

The MESO-BRAIN project facilitates a better understanding of human disease progression, neuronal growth and enables the development of large-scale human cell-based assays to test the modulatory effects of pharmacological and toxicological compounds on neural network activity. This can ultimately help to better understand and treat neurological conditions such as Parkinson’s disease, dementia, and trauma. In addition, the use of more physiologically relevant human models will increase drug screening efficiency and reduce the need for animal testing.

University at Buffalo (UB) researchers have developed a novel 3D printed water-purifying graphene aerogel that could be scaled for use at large wastewater treatment plants.

Composed of a styrofoam-like aerogel, latticed graphene and two bio-inspired polymers, the novel material is capable of removing dyes, metals and organic solvents from drinking water with 100% efficiency. Unlike similar nanosheets, the scientists’ design is reusable, doesn’t leave residue and can be 3D printed into larger sizes, thus they now aim to commercialize it for industrial-scale deployment.

“The goal is to safely remove contaminants from water without releasing any problematic chemical residue,” explained study co-author and assistant professor of environmental engineering at UB, Nirupam Aich. “The aerogels we’ve created hold their structure when put into water treatment systems, and they can be applied in diverse water treatment applications.”