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Researchers pioneer ‘green’ framework for sustainable drug development

Medical drugs are expensive to make and can have an adverse effect on the environment. Researchers Stefano Cucurachi and Justin Lian have developed a framework to help the health care system assess the economic and environmental sustainability of medical compounds. The research is published in the Proceedings of the National Academy of Sciences.

With a growing and aging population, and more people living with chronic disease, health care costs are rising and the is expanding fast. Patients and health care professionals are also beginning to wonder about the of medicines. But information on this is lacking.

“Some sources claim 10% of all pharmaceuticals have an environmental risk, but only the smallest fraction has ever been assessed,” says Cucurachi, Associate Professor of industrial ecology.

SCP-3812: The Entity That Broke Reality | The Science of a God Who Knows It’s Fiction

What happens when awareness grows too powerful for the universe that contains it?

SCP-3812 — also known as A Voice Behind Me — is the Foundation’s ultimate paradox: a being that rewrites existence every time it tries to understand itself. This speculative science essay explores the physics, metaphysics, and philosophy behind the phenomenon. From quantum observer effects to pancomputational cosmology, from the breakdown of time to the collapse of narrative itself, we ask the ultimate question:

What if consciousness doesn’t live inside reality, but creates it?

Join us as we explore:

- The origin of Sam Howell and post-mortem evolution of awareness.
- The science of unreality and the hierarchy of dimensions.
- Schizophrenia as multiversal cognition.
- Supersession, recursion, and the limits of containment.
- The final collapse of reality into pure perception.

If you love speculative science, existential philosophy, or cosmic horror wrapped in logic, this video will change the way you think about reality.

Tron: Ares | Official Trailer

Watch the brand-new trailer for Tron: Ares and experience it in theaters, filmed for IMAX, October 10.

Tron: Ares follows a highly sophisticated Program, Ares, who is sent from the digital world into the real world on a dangerous mission, marking humankind’s first encounter with A.I. beings. The feature film is directed by Joachim Rønning and stars Jared Leto, Greta Lee, Evan Peters, Hasan Minhaj, Jodie Turner-Smith, Arturo Castro, Cameron Monaghan, with Gillian Anderson, and Jeff Bridges. Sean Bailey, Jeffrey Silver, Justin Springer, Jared Leto, Emma Ludbrook and Steven Lisberger are the producers, with Russell Allen serving as executive producer.

Grammy®-award winning rock band Nine Inch Nails composed the score for “Tron: Ares,” and today, the band dropped \.

“I Became a GMO to Fight Aging” | Liz Parrish at Transvision Madrid 2025

Liz Parrish, founder and CEO of BioViva, delivers a compelling keynote on the revolutionary potential of gene therapy for human longevity and rejuvenation.

As one of the boldest voices in the longevity field and the first person to undergo experimental gene therapy for aging, Parrish shares her insights into how genetic interventions are ready to extend human healthspan.

Parrish challenges the status quo of medical research and advocates for faster translations of scientific advances, arguing that delayed access is costing millions of lives.

Direct evidence of universal anyon tunneling in a chiral Luttinger liquid revealed in edge-mode experiment

Electrons in two-dimensional (2D) systems placed under strong magnetic fields often behave in unique ways, prompting the emergence of so-called fractional quantum Hall liquids. These are exotic states of matter in which electrons behave collectively and form new quasiparticles carrying only a fraction of an electron’s charge and obeying unusual quantum statistics.

In the 1990s, physicists introduced a theory known as the chiral Luttinger liquid theory, which describes the collective movements of these fractional excitations moving in 1D channels along the boundary of 2D fractional quantum Hall states. Nonetheless, past experimental findings were not always aligned with theoretical predictions.

Researchers at Purdue University recently carried out a study aimed at further testing some of the predictions of chiral Luttinger liquid theory by measuring tunneling between 1D edge modes in a device in which a fractional quantum Hall liquid state emerges. Their paper, published in Nature Physics, offers direct experimental evidence of universal anyon tunneling for the n=1/3 fractional quantum Hall state, confirming theoretical predictions made by X.-G. Wen and collaborators in the early 1990s.

Leveraging AI in the Early Detection of Pancreatic Cancer | Tomorrow’s Cure Season 2 Episode 7

A recent breakthrough from Mayo Clinic researchers offers new hope. Using the world’s largest imaging dataset, Mayo Clinic’s team has developed a cutting-edge AI model capable of detecting pancreatic cancer on standard CT scans—when surgery is still an option. This breakthrough represents a leap forward in the fight against pancreatic cancer, with the potential to save lives. Learn more about this life-changing innovation in early cancer detection. Featured experts include Ajit Goenka, M.D., radiologist and professor of radiology at Mayo Clinic’s Comprehensive Cancer Center and Suresh Chari, M.D., professor, Department of Gastroenterology, Hepatology, and Nutrition in the Division of Internal Medicine at MD Anderson Cancer Center. Subscribe to Tomorrow’s Cure wherever you get your podcasts. Visit tomorrowscure.com for more information.

This podcast is for informational purposes only and should not be relied upon as professional, medical or legal advice. Always consult with a qualified health care provider for any medical advice. The appearance of any guest does not imply an endorsement of them, their employer, or any entity they represent. The views and opinions are those of the speakers and do not necessarily reflect the views of Mayo Clinic. Reference to any product, service or entity does not constitute an endorsement or recommendation by Mayo Clinic.

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Geologists discover the first evidence of 4.5-billion-year-old ‘proto Earth’

Scientists at MIT and elsewhere have discovered extremely rare remnants of “proto Earth,” which formed about 4.5 billion years ago, before a colossal collision irreversibly altered the primitive planet’s composition and produced Earth as we know today. Their findings, reported today in the journal Nature Geosciences, will help scientists piece together the primordial starting ingredients that forged early Earth and the rest of the solar system.

Billions of years ago, the early solar system was a swirling disk of gas and dust that eventually clumped and accumulated to form the earliest meteorites, which in turn merged to form proto Earth and its neighboring planets.

In this earliest phase, Earth was likely rocky and bubbling with lava. Then, less than 100 million years later, a Mars-sized meteorite slammed into the infant planet in a singular “giant impact” event that completely scrambled and melted the planet’s interior, effectively resetting its chemistry. Whatever original material proto Earth was made from was thought to have been altogether transformed.

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