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Norway Halts Power Connections for New Data Centers

Norway will suspend further reservation of electricity connections for data centers while the country figures out how to handle the burden they place on the grid.

The measures introduced involve a temporary halt in new connection reservations, system operator Statnett AS said in a statement Monday. The halt is expected to be lifted no later than Aug. 1, 2027.

A quantum breakthrough makes light behave like both a solid and a liquid

Scientists have demonstrated an extraordinary form of quantum matter that combines two properties that seem incompatible. Known as a supersolid, this unusual state has the orderly structure of a crystal while also displaying the frictionless flow associated with a special kind of liquid. Even more remarkably, researchers have now observed this behavior at room temperature, eliminating the need for the extreme cooling traditionally used to investigate such phenomena.

The breakthrough was achieved by an international team from the Faculty of Physics at the University of Warsaw, the Military University of Technology (Poland), IBM Research Zurich, and the French National Centre for Scientific Research (CNRS). Rather than relying on atoms cooled to temperatures near absolute zero, the scientists created a supersolid using particles that combine properties of light and matter.

In rain and darkness, how should self-driving cars trust their sensors?

Many of today’s self-driving cars “see” the road through two senses at once. Cameras capture color, texture and the outline of a pedestrian, while light detection and ranging (LiDAR) fires laser pulses to measure exactly how far away that pedestrian stands. Together, they provide complementary information and outperform either sensor alone.

This pairing has a weakness, however. Trained mostly on clear daytime footage, the fusion model learns to lean on whichever sensor performs best there and may fail in challenging scenarios. Rain can scatter LiDAR beams, for instance, while a night drive leaves cameras battling darkness and glare.

To address this, assistant professor Zhao Na at Singapore University of Technology and Design (SUTD) led two studies that built different models. In “CCF: Complementary collaborative fusion for domain generalized multi-modal 3D object detection,” the research team rebalances how a detector weighs its sensors so it holds up in new surroundings. In “PanDA: Unsupervised domain adaptation for multimodal 3D panoptic segmentation in autonomous driving,” they harness unlabeled data from a new environment to help the model adapt once it arrives.

The JAK2 V617F revolution in myeloproliferative neoplasms

1951, William Dameshek (1900−1969) penned an editorial in Blood highlighting shared phenotype (i.e., trilineage proliferation, splenomegaly, bone marrow fibrosis) among the myeloproliferative and related myeloid neoplasms, including chronic myeloid leukemia (CML; then referred to as “chronic granulocytic leukemia”), polycythemia vera (PV), essential thrombocythemia (ET; then referred to as “megakaryocytic leukemia”), and primary myelofibrosis (PMF; then referred to as “idiopathic or agnogenic myeloid metaplasia of spleen”).1 He also discussed transitional (e.g., post-PV myelofibrosis) and pre-fibrotic states and contended that these “myeloproliferative disorders” were closely interrelated and represented variable manifestations of a constitutively-driven bone marrow proliferative activity arising from a “hitherto undiscovered stimulus”.1

In 1960, Nowell and Hungerford described the Philadelphia chromosome that ultimately led to the identification of BCR::ABL1 as the disease-causing mutation in CML and the successful launching of imatinib (ABL tyrosine kinase inhibitor) as a disease-modifying drug therapy. By contrast, the molecular basis of PV, ET, and PMF remained elusive until the March, 2005 breakthrough communication by James et al., describing a novel Janus kinase 2 JAK/STAT activating mutation (JAK2V617F located in the auto-inhibitory JH2 pseudo-kinase domain — a G to T somatic mutation at nucleotide 1849, in exon 14, resulting in the substitution of valine to phenylalanine at codon 617) in PV, ET and PMF (discovery patent filing in October 2004).2 The authors utilized short interfering RNA to knock down JAK2 expression and demonstrated the essential role of JAK2 in erythropoietin-independent growth in PV (Figure 1).

A sweeter future? AI helps scientists discover new sugar substitutes

Researchers Dr. Shayma El-Atawneh and professor Amiram Goldblum at the Hebrew University of Jerusalem have developed a new computational framework that identified 92 promising candidates for future sugar substitutes from more than 50 million chemical compounds. The study, published in the journal Food Chemistry, demonstrates how artificial intelligence and molecular modeling could accelerate the discovery of new sweeteners while helping overcome one of the industry’s persistent challenges: unwanted bitter aftertastes.

As demand for low-calorie sugar alternatives grows, scientists are seeking sweeteners that provide pleasant taste along with favorable safety and stability profiles. Excessive sugar consumption has been linked to several health and environmental concerns. High sugar intake can increase the risk of obesity, type 2 diabetes, fatty liver disease and cardiovascular disorders. The FDA has approved artificial sweeteners and established recommended daily amounts per kilogram for each.

However, widely used artificial sweeteners such as aspartame, saccharin and sucralose have limitations, including bitter or metallic aftertastes. Discovering new compounds that are sweet without undesirable characteristics remains a significant challenge.

Black hole spotted near the Big Bang has astronomers scratching their heads for one key reason

Found in the centre of a galaxy known as, it’s the most distant black hole ever confirmed and a rare glimpse into the cosmic dawn.

The black hole was spotted by an international team of astronomers led by the Cosmic Frontier Center at the University of Texas at Austin, using data from the James Webb Space Telescope.

“When looking for black holes, this is about as far back as you can practically go,” says Anthony Taylor, a postdoctoral researcher at the centre.

Epigenetic Editing Could Wipe Out Chronic Hepatitis B Infections

Viruses are sneaky things. When they die, their DNA often sticks around. Some of them transform into freely roaming DNA that evades treatment. Others tunnel into their host’s genome and lie dormant, sometime for decades.

But dormant doesn’t mean gone. When the time is right, they strike. If a patient with hepatitis B virus (HBV) or HIV stops taking antiviral drugs, it can trigger a severe rebound of the disease. Stress, aging, and other factors that dampen the immune system can also reactivate the chickenpox virus, triggering the painful, blistering rash known as shingles.

Now, scientists have found a way to shut down one of these biological sleeper agents. Called epigenetic silencing, the technology hunts down lingering HBV genes in infected mice and adds a chemical tag that switches the genes off, without cutting the viral DNA. Unlike gene editing tools that shred genetic material, potentially causing collateral damage to the host’s genome, the epigenetic approach could be safer but still long-lasting.

MIT scientists turn immune cells into cancer killers inside the body

MIT scientists have developed nanoparticles that reprogram immune cells directly inside the body to attack cancer and harmful immune cells, eliminating tumors and reversing liver damage in mouse experiments. The breakthrough could make powerful immune therapies dramatically simpler and less expensive while opening new possibilities for treating cancer and autoimmune diseases.

Taiwan-Based Hacker Used BOSSAI AI Agents to Steal Taipei Emergency Dispatch Records

A single attacker using AI agents pulled emergency dispatch records covering seven Taipei districts, researchers at Acronis’s Threat Research Unit said last week.

The agents also found a Taipei fire department platform exposing patient data from 2018, including ECG readings and ambulance video footage, without a login.

The researchers are highly confident that the attacker is a single person based in Hualien City, Taiwan. He aimed the agents at hundreds of organizations in at least 11 countries, including emergency services, banks, universities and military systems. The agents collected data or accessed systems at about 10 of them in Taiwan, Mexico and Thailand.