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Blog – Page 975

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Scientists Trace Lupus to One of The World’s Most Common Viruses

One of the world’s most common viral infections could underlie virtually every case of lupus, according to a recent study providing the strongest evidence yet for a link.

The research, led by scientists at Stanford University, has found that the Epstein-Barr virus (EBV) could be the trigger behind the ‘cruel mystery’

EBV is the pathogen that causes ‘kissing disease’ (or mononucleosis), and according to the new findings, it can directly infect and reprogram specific immune cells, potentially driving the onset of the chronic autoimmune disease systemic lupus erythematosus – better known as simply lupus.

Degradation and Failure Phenomena at the Dentin Bonding Interface

Damage in the bonding interface is a significant factor that leads to premature failure of dental bonded restorations. The imperfectly bonded dentin-adhesive interface is susceptible to hydrolytic degradation and bacterial and enzyme attack, severely jeopardizing restorations’ longevity. Developing caries around previously made restorations, also called “recurrent or secondary caries,” is a significant health problem. The replacement of restorations is the most prevailing treatment in dental clinics, leading to the so-called “tooth death spiral”. In other words, every time a restoration is replaced, more tooth tissue is removed, increasing the size of the restorations until the tooth is eventually lost. This process leads to high financial costs and detriment to patients’ quality of life.

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