Monitoring markers of tau protein in the blood can predict functional outcomes in patients recovering from ischemic stroke better than MRI, according to a comprehensive study of more than 1,200 patients in ScienceTranslationalMedicine.
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Sci. Transl. Med. 18, eadz1280 (2026). DOI:10.1126/scitranslmed.adz1280
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Controlling myelin sheath geometry!
Mechanics of how oligodendrocytes, the myelinating cells of the brain, insulates the axons for proper signal transduction across the neurons is not well understood.
The researchers in this study show that oligodendrocytes use mechanical cues to measure axon size.
Loss of TMEM63A causes mis-sizing of myelin sheaths and hypomyelination linked to transient infantile leukodystrophy. https://sciencemission.com/TMEM63A-regulates-myelin-sheath
Dereddi, Djannatian, and colleagues show that oligodendrocytes use mechanical cues to measure axon size. The stretch-activated channel TMEM63A converts membrane tension into calcium signals, which calibrate myelin sheath growth via MYO5A-dependent Mbp mRNA transport. Loss of TMEM63A causes mis-sizing of myelin sheaths and hypomyelination linked to transient infantile leukodystrophy.
Earthâs oceans reached their highest heat levels on record in 2025, absorbing vast amounts of excess energy from the atmosphere. This steady buildup has accelerated since the 1990s and is now driving stronger storms, heavier rainfall, and rising sea levels. While surface temperatures fluctuate year to year, the oceanâs long-term warming trend shows no sign of slowing.
SpaceX is well-positioned to dominate the future of space AI due to its innovative technologies, scalable satellite production, and strategic partnerships, which will enable it to efficiently deploy and operate a massive network of satellites with advanced computing capabilities ## ## Questions to inspire discussion.
Launch Economics & Infrastructure.
đ Q: Why is Starship essential for space AI data centers? A: Starship enables 100-1000x more satellites than Falcon 9, making orbital AI economically viable through massive scaling and lower launch costs, while Falcon 9 remains too expensive for commercial viability at scale.
đ°ïž Q: What is SpaceXâs deployment plan for AI satellites? A: SpaceX plans Starlink version 3 satellites with 100 Nvidia chips each, deploying 5,000 satellites via 100 Starship launches at 50 satellites per flight to create a gigawatt-scale AI constellation by early 2030s.
đ Q: What launch cadence gives SpaceX its advantage? A: SpaceX plans 10,000 annual launches and produces satellites at 10-100x the level of competitors, creating a monopoly on launch and manufacturing that positions them as the gatekeeper to space AI success.
Energy & Power Systems.
A team using NASAâs Hubble Space Telescope has uncovered a new type of astronomical object â a starless, gas-rich, dark-matter cloud considered a ârelicâ or remnant of early galaxy formation. Nicknamed âCloud-9,â this is the first confirmed detection of such an object in the universe â a finding that furthers the understanding of galaxy formation, the early universe, and the nature of dark matter itself.
âThis is a tale of a failed galaxy,â said the programâs principal investigator, Alejandro Benitez-Llambay of the Milano-Bicocca University in Milan, Italy. âIn science, we usually learn more from the failures than from the successes. In this case, seeing no stars is what proves the theory right. It tells us that we have found in the local universe a primordial building block of a galaxy that hasnât formed.â
The results, published in The Astrophysical Journal Letters, were presented at a press conference Monday at the 247th meeting of the American Astronomical Society in Phoenix.
The math behind Evo-devo~
Uri Alonâs Book:
Jim Collins paper:
https://www.researchgate.net/publication/12654725_ConstructiâŠichia_coli.
https://www.nature.com/articles/s41467-017-01498-0
The math behind fly development:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.
Music:
City Life â Artificial. Music (No Copyright Music)
Link: https://www.youtube.com/watch?v=caT3j⊠ure Water by MeydĂ€n Link: âą MeydĂ€n â Pure Water [Creative Commons â CC⊠Forever Sunrise â by Jonny Easton Link:
âą Forever Sunrise â Soft Inspirational Piano⊠Softwares used: Manim CE Keynote.
Pure Water by MeydÀn.
Link: https://youtu.be/BU85yzb0nMU
Forever Sunrise â by Jonny Easton.
Link: https://youtu.be/9Xndx7nhGAs.
Softwares used:
An exploration of simulation theory from the standpoint of what would happen if the whole thing became corrupted?
My Patreon Page:
/ johnmichaelgodier.
My Event Horizon Channel:
/ eventhorizonshow.
Music.