Lifeboat Foundation

An ancient brain circuit, which enables the eyes to reflexively rotate up as the body tilts down, tunes itself early in life as an animal develops, a new study finds.

Led by researchers at NYU Grossman School of Medicine, the study revolves around how vertebrates, which include humans and animals spanning evolution from primitive fish to mammals, stabilize their gaze as they move. To do so, they use a brain circuit that turns any shifts in orientation sensed by the balance (vestibular) system in their ears into an instant counter-movement by their eyes.

The research is published in the journal Science.

Blog: Aadyot Bhatnagar and Stephen Nayfach — Jan 7, 2025.

As computer chips continue to get smaller and more complex, the ultrathin metallic wires that carry electrical signals within these chips have become a weak link. Standard metal wires get worse at conducting electricity as they get thinner, ultimately limiting the size, efficiency, and performance of nanoscale electronics.

In a paper published in Science, Stanford researchers show that niobium phosphide can conduct electricity better than copper in films that are only a few atoms thick. Moreover, these films can be created and deposited at sufficiently low temperatures to be compatible with modern computer chip fabrication. Their work could help make future electronics more powerful and more energy efficient.

“We are breaking a fundamental bottleneck of traditional materials like copper,” said Asir Intisar Khan, who received his doctorate from Stanford and is now a visiting postdoctoral scholar and first author on the paper.

Sarah Cohen and two others will pioneer a method to view these molecular structures and their interactions in live stem cells.

In this interview, I sit down with Simon Critchley, Hans Jonas Professor of Philosophy at The New School for Social Research in New York, to explore his provocative new book, On Mysticism. Drawing on medieval Christian figures like Julian of Norwich and Marguerite Porete, Critchley argues that ecstatic experience, intense love, and a willingness to be “outside oneself” can offer a counterbalance to the narrowly rational outlook dominant in modern philosophy. Throughout our conversation, he probes the boundaries of faith and reason, discuss the possibility of maintaining mysticism alongside science, and question the role of philosophy itself in shaping our cultural consciousness. What follows is only a short, edited extract from Critchley’s call for more openness, both in our thinking and our collective search for meaning. Link to the full interview.

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Profluent unveils Protein2PAM AI model to design CRISPR systems targeting more of human genome, CEO Ali Madani announces. Tool predicts PAM sequences for expanded gene editing.

Researchers at the University of Oklahoma have developed a breakthrough method of adding a single nitrogen atom to molecules, unlocking new possibilities in drug research and development. Now published in the journal Science, this research is already gaining international attention from drug manufacturers.

Nitrogen atoms and nitrogen-containing chemical structures, called heterocycles, play a pivotal role in medicinal chemistry and drug development. A team led by OU associate professor Indrajeet Sharma has demonstrated that by using a short-lived chemical called sulfenylnitrene, researchers can insert one nitrogen atom into bioactive molecules and transform them into new pharmacophores that are useful for making drugs.

This process is called skeletal editing and takes inspiration from Sir Derek Barton, the recipient of the 1969 Nobel Prize in Chemistry.

A new theory akin to the second law of thermodynamics describes the motion of active biological systems ranging from migrating cells to traveling birds.

W/ Dr. Haofei Yu of University of illinois.

Speakers: Cecile Tamura, Haofei Yu