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In this work, Vigo et al. demonstrate that norepinephrine (NE) promotes myeloid hematopoiesis in BM and regulates thymic Tregs via B3ARs in EAE. B3ARs are controlled by hypothalamic AgRP neurons, which are dysfunctional in EAE. Serum levels of AgRP are elevated in people with MS and correlate with disease severity.
Winter’s chill impacts children’s health, increasing illness and affecting growth due to reduced sunlight, indoor confinement, and dietary shifts. Experts advise parents to prioritize balanced nutrition, adequate sleep, and physical activity. Simple measures like hygiene, vaccinations, and sun exposure are crucial for keeping kids healthy and thriving throughout the colder months.
A heart attack is a medical emergency that requires an immediate call to the emergency services. However, there are sometimes warning signs that can show up weeks in advance that should prompt you to visit your doctor.
Firstly, what exactly happens during a heart attack? A heart attack occurs when the vessels that supply the heart itself with oxygen and nutrients—known as coronary arteries—become blocked. One cause is calcium deposits building up in them, says the German Heart Foundation.
As this is a gradual process, symptoms often appear before the blockage occurs, when the vessels are already narrowed in what is referred to as coronary heart disease.
Scientists in China have performed an experiment first proposed by Albert Einstein almost a century ago when he sought to disprove the quantum mechanical principle of complementarity put forth by Niels Bohr and his school of physicists. Bohr claimed there are properties of particles that cannot simultaneously be measured. The new result backs up the Copenhagen school yet again, with the potential to shed light on other, less settled questions in quantum mechanics.
When they met at physics conferences, Albert Einstein and Niels Bohr liked to kick back and debate about quantum mechanics. Einstein, always skeptical of the standard picture of quantum mechanics then being developed, liked to claim he had found holes and inconsistencies in Bohr’s interpretation, and Bohr was always up for the challenge.
At the 1927 Solvay conference in Brussels, the two Nobel Laureates had perhaps their most famous parley, with Einstein famously proclaiming, “God does not play dice with the universe.” In particular, Einstein proposed an experiment he thought would reveal the essential contradiction in the principle of complementarity, which held that pairs of properties of particles, such as position and momentum, and frequency and lifetime, cannot be measured at the same time. Complementarity undergirds the concepts of wave-particle duality and Heisenberg’s uncertainty principle.
WASHINGTON, DC (KOAA) — As NASA looks to return to the moon’s surface in the near future, Colorado company Lunar Outpost is one of three companies currently competing for a multi-billion dollar contract from the space agency for a new Lunar Terrain Vehicle (LTV).
On Monday, NASA indicated to KOAA the long-awaited decision could finally be made in the coming weeks of early 2026. NASA’s contract could have a combined maximum potential value of $4.6 billion for all awards.
Memories and learning processes are based on changes in the brain’s neuronal connections and, as a result, in signal transmission between neurons. For the first time, DZNE researchers have observed an associated phenomenon in living brains – specifically in mice. This mechanism concerns the cellular pulse generator for neuronal signals (the “axonal initial segment”) and had previously only been documented in cell cultures and in brain samples. A team led by neuroscientist Jan Gründemann reports on this in the journal Nature Neuroscience, alongside experts from Switzerland, Italy, and Austria. Their study sheds light on the brain’s ability to adapt. Next, the researchers intend to investigate the significance of these findings in Alzheimer’s disease.
In the brain, neurons branch out and connect with each other to form a network through which electrical signals are actively exchanged. This network structure is an essential component of the brain’s “hardware” and is therefore fundamental to its function, especially with regard to learning processes and memory formation. However, this complex architecture and signal transmission across this network are not fixed; they can change as a result of experiences and events. This flexibility, also known as neuroplasticity, is the basis for the brain’s ability to adapt.
As memories are formed, the brain changes in measurable ways: synaptic “pulse generators” grow and shrink, revealing surprising insights from brain research.
npj Computational Materials, Article number: (2025) Cite this article
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