Turning cancer cells into zombie cells then destroying them with senolytic therapy for a double whammy against cancer!
Using a combination of therapies to turn cancer cells into non-dividing zombie cells then destroying them with could soon become the way we treat cancer without the need for harsh chemotherapy.
#aging #cancer
If you’re not paying attention to what’s going on in energy, you should. We’ve seen this movie before. Spoiler alert: There’s massive economic opportunity ahead. How massive? Imagine standing in 1992, knowing that Google, Akamai, Netflix, Facebook, Amazon, eBay, BuzzFeed and Uber lay ahead.
This time it’s the “enernet,” not the internet, that will transform our lives. The story is the same, though the players have changed.
Here’s the tee up. Across the country, incumbent network providers operate highly centralized networks in their respective cities. Then, scrappy local outfits start serving the market with innovative, distributed technology. These startups create competition, and a new network emerges atop the legacy network.
Posted in media & arts, robotics/AI, singularity
Carrie Fisher just died but she will likely come back to life because the Singularity is Near and is bringing Singularity CGI with it!
In the latest Star Wars movie, Rogue One, five characters were brought back as they would have looked between episodes 3 and 4 of Star Wars. They were Princess Leia, Grand Moff Tarkin, Dr. Cornelius Evazan (who said “I have the death sentence on twelve systems” in episode 4), General Dodonna, and Mon Mothma. General Dodonna and Mon Mothma were brought back with the traditional method of using actors who looked similar to the original actors. The other three were brought back with CGI (computer-generated imagery), more specifically CGI enhanced with motion capture.
Motion capture has been used for a while including depicting Gollum in Lord of the Rings and all the apes in the latest Planet of the Apes movies but Grand Moff Tarkin was considered possibly too hard to do with today’s technology because people are better at seeing flaws in CGI humans than CGI apes and CGI twisted hobbits.
Here is how Grand Moff Tarkin was created:
English actor Guy Henry (Harry Potter) wore motion capture materials on his head so that his face could eventually be replaced with a digital likeness of Cushing’s (the original actor for Moff Tarkin). He was picked because he had a similar build and stature as Cushing and was able to speak in a similar manner.
John Knoll, the chief creative officer at Industrial Light & Magic, wasn’t sure they were going to be able to pull this off. He said, “We did talk about Tarkin participating in conversations via hologram, or transferring that dialogue to other characters.” Tarkin ended up looking pretty good (actually fooling some critics!) although Dr. Evazan looked even better for his scene mostly because his distorted face doesn’t look completely human.
Was this CGI good enough to envision Princess Leia having a significant role using this technology? Probably not. But something amazing happened in 2016. Nvidia completed an over $2 billion project to develop a new class of graphics/AI chips. An example of how good they were is that the new version of the Nvidia Titan X can do AI (artificial intelligence) 566% faster than the previous Titan X that was only released a year before. This $1,200 card is so popular that half a year after its release Nvidia is still rationing this card to two per customer. (Disney gets to use Nvidia cards that are even more powerful than the Titan X!)
Why does Nvidia matter to Star Wars fans? Because Nvidia’s chips power the CGI in virtually all movies. Nvidia is now making 100% of the profits of all companies selling graphics cards, with their chips being put into everything from Nintendo’s newest console to every Tesla car currently being built. This has caused Nvidia to soar in value, with their stock over tripling in 2016. This means that Nvidia is going to be able to spend a lot more than $2 billion on their next generation of graphics/AI chips! (Nvidia has found a way to use about the same architecture for AI chips and regular graphics chips.)
Not only is Nvidia’s new graphics/AI chip design affecting movies but they are helping make Ray Kurzweil’s prediction of human equivalent AI by 2029 a reality. Nvidia’s CEO Jen-Hsun Huang said, “AI is going to increase in capability faster than Moore’s Law. I believe it’s a kind of a hyper Moore’s Law phenomenon because it has the benefit of continuous learning. It has the benefit of large-scale networked continuous learning. Today, we roll out a new software package, fix bugs, update it once a year. That rhythm is going to change. Software will learn from experience much more quickly. Once one smart piece of software on one device learns something, then you can over-the-air (OTA) it across the board. All of a sudden, everything gets smarter.”
Nvidia’s improved chips are part of a three layer accelerating returns juggernaut that is affecting CGI and which we will call Singularity CGI.
Layer one of Singularity CGI is better hardware with Nvidia having just switched from 28 nanometer transistors to 16/14 nanometer transistors. (They are getting 16 nanometer technology from TSMC and 14 nanometer from Samsung.) A 14 nanometer part is only 140 atoms wide! Both Samsung and TSMC will be producing 10 nanometer parts in 2017, with large Nvidia parts likely in 2018. (The 10 nanometer parts in 2017 will be for companies like Apple who don’t need large, complex chips as Nvidia does.)
Layer two of Singularity CGI is better Nvidia designs which is what Nvidia just spent over two billion dollars on. Layer three of Singularity CGI is better software. An example of this exponentially improved software is that Disney Research and Carnegie Mellon University scientists have found that three computer vision methods commonly used to reconstruct 3D scenes produce superior results in capturing facial details when they are performed simultaneously, rather than independently.
“The quality of a 3D model can make or break the perceived realism of an animation,” said Paulo Gotardo, an associate research scientist at Disney Research. “That’s particularly true for faces; people have a remarkably low threshold for inaccuracies in the appearance of facial features. PGSF (photogeometric scene flow) could prove extremely valuable because it can capture dynamically moving objects in high detail and accuracy.”
The growing power of Singularity CGI means that when Disney is ready to release episode 9 in 2019, Disney will be able to use much more powerful Nvidia cards and more sophisticated software to bring Carrie Fisher back to life to finish her story whose first two parts were in The Force Awakens (episode 7) in 2015 and episode 8 in 2017. (Carrie already filmed her scenes for episode 8.)
To increase the chance of success of creating a realistic Carrie Fisher, Disney will even be given $50 million thanks to insurance through Lloyd’s of London to fund this effort. May the force be with us!
In Brief
Concealing objects in direct light is already a difficult feat. While there is ongoing research into invisibility cloaks of some form or other, researchers at the Public University of Navarre (NUP/UPNA) and the Universitat Politècnica de València (UPV) are taking a not-so-straightforward approach. In particular, they are interested in developing a cloaking mechanism that works by bending light.
The team, whose work is published in the journal Physical Review A, has worked on simulations of an invisibility technology that conceals objects in diffusive atmospheres. This kind of invisibility, based on their study, can be achieved by surrounding an object with a special material that’s capable of bending light around it.
Bullfights arouse strong feelings on both sides. Their aficionados see them as a place of near reverence, where animal and man engage in an athletic dance summoning the shadows of mankind’s struggles for both dominance over and stewardship of his natural counterparts. Opponents of the sport decry its violence and bloodshed, the unnecessary cruelty of what they see as a prolonged infliction of torture upon one of our planet’s fellow creatures. In 2012, Catalonia, the region of Spain that contains Barcelona, agreed more with the latter characterization than the former and banned the sport.
Posted in futurism
Posted in futurism
The future of nuclear power might look very different than we thought, with a US-based company presenting plans for miniature, modular nuclear power plants that are so small, they can fit on the back of a truck.
NuScale Power, the company behind the power plants, says each modular device is completely self-contained, and capable of producing 50-megawatts of electricity — enough to power thousands of homes.
The power plants stand 29.7 metres tall, so aren’t really that ‘miniature’, except relative to an acutal nuclear power plant. They also haven’t been tested as yet, so we need to reserve our excitment for when we can actually see these things in action.
