Lifeboat Foundation

In the adult brain, synapses are tightly enwrapped by lattices of the extracellular matrix that consist of extremely long-lived molecules. These lattices are deemed to stabilize synapses, restrict the reorganization of their transmission machinery, and prevent them from undergoing structural or morphological changes. At the same time, they are expected to retain some degree of flexibility to permit occasional events of synaptic plasticity. The recent understanding that structural changes to synapses are significantly more frequent than previously assumed (occurring even on a timescale of minutes) has called for a mechanism that allows continual and energy-efficient remodeling of the extracellular matrix (ECM) at synapses. Here, we review recent evidence for such a process based on the constitutive recycling of synaptic ECM molecules. We discuss the key characteristics of this mechanism, focusing on its roles in mediating synaptic transmission and plasticity, and speculate on additional potential functions in neuronal signaling.

An increasing number of studies are showing that synaptic function is strongly influenced by their local environment, including the molecules or cellular components in their vicinity. As a result, the classical synaptic framework (consisting of the pre-and postsynaptic compartments only) has gradually been extended to include the neighboring astrocytic processes (the “tripartite synapse”; Araque et al., 1999) and, ultimately, also the surrounding extracellular matrix (ECM; the “tetrapartite synapse”; Dityatev et al., 2006). Nowadays, the synaptic ECM is recognized to play an essential role in physiological synaptic transmission as well as in plasticity, and its dysregulation has been linked to synaptopathies in a wide variety of brain disorders (Bonneh-Barkay and Wiley, 2009; Pantazopoulos and Berretta, 2016; Ferrer-Ferrer and Dityatev, 2018).

10 SpaceX Starships are carrying 120 robots to Mars. They are the first to colonize the Red Planet. Building robot habitats to protect themselves, and then landing pads, structures, and the life support systems for the humans who will soon arrive.

This Mars colonization mini documentary also covers they type of robots that will be building on Mars, the solar fields, how Elon Musk and Tesla could have a battery bank station at the Mars colony, and how the Martian colony expands during the 2 years when the robots are building. Known as the Robotic Age of Mars.

Continue reading “THE FIRST 2 YEARS ON MARS (Prequel) Timelapse” »

Scientists have devised a way of fabricating a complex structure, previously found only in nature, to open up new ways for manipulating and controlling light.

The structure, which naturally occurs in the wing scales of some species of butterfly, can function as a photonic crystal, according to a new study by researchers at the University of Birmingham. It can be used to control light in the visible range of the spectrum, for applications for lasers, sensors, and also devices for harvesting solar energy.

Their computational study, published in Advanced Materials, demonstrates that the complex gyroid structure can be self-assembled from designer colloidal particles in the range of hundreds of nanometers.

In 1960, visionary physicist Freeman Dyson proposed that an advanced alien civilization would someday quit fooling around with kindergarten-level stuff like wind turbines and nuclear reactors and finally go big, completely enclosing their home star to capture as much solar energy as they possibly could. They would then go on to use that enormous amount of energy to mine bitcoin, make funny videos on social media, delve into the deepest mysteries of the Universe, and enjoy the bounties of their energy-rich civilization.

But what if the alien civilization was… us? What if we decided to build a Dyson sphere around our sun? Could we do it? How much energy would it cost us to rearrange our solar system, and how long would it take to get our investment back? Before we put too much thought into whether humanity is capable of this amazing feat, even theoretically, we should decide if it’s worth the effort. Can we actually achieve a net gain in energy by building a Dyson sphere?

Year 2022 😗😁

The Climate Foundation’s SeaForestation project has won a Milestone XPRIZE for carbon removal, from Elon Musk’s foundation.

According to the prize’s official site, the competition “is aimed at tackling the biggest threat facing humanity — fighting climate change and rebalancing Earth’s carbon cycle”.

Continue reading “Seaweed project wins million dollar XPRIZE for carbon removal” »

Year 2022 Permaculture once a sorta outcast of the science world is now seen as the forefront of carbon capture for climate change 😀 😉

Since late 2021, WSP has been supporting the Climate Foundation in an exciting project to develop a prototype design for Marine Permaculture Arrays.

An oil tanker abandoned and anchored in the Red Sea could produce an oil spill that would spread over the southern half of the body of water and block ports, close desalination plants, and produce a food and water crisis for the people of Yemen.

A UN rescue plan for the rusting tanker off Yemen’s coast has ballooned in cost to $129 million. So far money raised is $34 million short.

Saw this coming 5 or 10 years back. Soon concept of being a model will be non existent. Probably by 2030. And, once can realistically animate and walk around and speak, end of actors and acting also.

Levi’s is partnering with an AI company on computer-generated fashion models to “supplement human models.” The company frames the move as part of a “digital transformation journey” of diversity, equity, inclusion and sustainability. Although that sounds noble on the surface, Levi’s is essentially hiring a robot to generate the appearance of diversity while ridding itself of the burden of paying human beings who represent the qualities it wants to be associated with its brand.

Levi Strauss is partnering with Amsterdam-based digital model studio Lalaland.ai for the initiative. Founded in 2019, the company’s mission is “to see more representation in the fashion industry” and “create an inclusive, sustainable, and diverse design chain.” It aims to let customers see what various fashion items would look like on a person who looks like them via “hyper-realistic” models “of every body type, age, size and skin tone.”

Continue reading “Levi’s will ‘supplement human models’ with AI-generated fakes” »

Researchers have ‘hacked’ the earliest stages of photosynthesis, the natural machine that powers the vast majority of life on Earth, and discovered new ways to extract energy from the process, a finding that could lead to new ways of generating clean fuel and renewable energy. We didn’t know as.