Lifeboat Foundation

Our brains change more rapidly at various times of our lives, as though life’s clock was ticking faster than usual. Childhood, adolescence and very old age are good examples of this.

Yet for much of adulthood, the same clock seems to tick fairly regularly. One lap around the Sun; one year older.

However, there may be a stage of life when the brain’s clock starts speeding up. The brain starts changing without you necessarily noticing it. It may even be caused (partly) by what’s in your blood.

Multiple Australian projects are on the cutting edge of neurotech breakthroughs and man-machine interfaces – raising questions of security and privacy for human minds.

We made Dr. K’s Guide to ADHD and Doing Stuff so you can focus on the things you actually want to. It is full of lectures, neuroscience, worksheets, meditation, and more. Check it out today: https://bit.ly/3qvHKBr.

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Researchers have made a pioneering discovery that astrocytes, cells within the central nervous system traditionally not associated with immune functions, are capable of developing what’s being called an “immune memory.” This capability…

Summary: Astrocytes, traditionally non-immune cells within the central nervous system, possess the ability to develop an immune memory, responding more vigorously to subsequent immune challenges. This groundbreaking study reveals that through an epigenetic mechanism involving the enzymes p300 and ATP-citrate lyase (ACLY), astrocytes enhance their pro-inflammatory responses, a trait similar to the immune memory seen in adaptive immunity.

The findings, which have been observed in both mouse models of multiple sclerosis (MS) and human cell samples, suggest that astrocyte immune memory may play a significant role in chronic neurological disorders, offering new insights into disease pathology and potential therapeutic targets to mitigate CNS inflammation.

New breakthrough research shows that a simple blood test can flag symptoms of Alzheimer’s Disease up to 15 years in advance.

https://www.news-medical.net/news/20240320/Study-highlights-…idism.aspx Frontiers

In a recent study published in Frontiers in Nutrition, researchers explored the association between the microbial community of the gut and hypothyroidism.

Study: Cross-talk between the gut microbiota and hypothyroidism: a bidirectional two-sample Mendelian randomization study. Image Credit: sdecoret/Shutterstock.com.

Continue reading “Study highlights causal associations between gut microbes and hypothyroidism” »

As the world inches ever closer to mind-reading technology, some scientists are calling to legally enshrine the right to keep our thoughts to ourselves.

In interviews with Undark, neuroscientists — including those who are working to make these so-called brain-computer interfaces (BCIs) happen — revealed their concerns about the devices.

In one particularly telling exchange, a pair of researchers from the University of Texas at Austin who’ve successfully created a BCI that can rudimentarily translate brain waves into text described how it felt to realize their device was actually reading their thoughts.

A recent study explored a potential connection between obstructive sleep apnea (OSA) and bladder pain syndrome/interstitial cystitis (BPS/IC) in women. The findings published in the Sleep and Breathing Journal underline the importance of understanding the interplay between sleep disorders and urological conditions.

This study investigated the frequency of BPS/IC in women diagnosed with OSA when compared to those without OSA. A total of 92 women participated, where 46 were diagnosed with OSA and an equal number serving as the control group. Various assessments including the Berlin Questionnaire, Epworth Sleepiness Scale, Interstitial Cystitis Symptom Index (ICSI) and Interstitial Cystitis Problem Index (ICPI) were evaluated in all participants.

The results revealed that women with OSA expressed higher scores on the Epworth Sleepiness Scale which indicates increased daytime sleepiness, while there were no significant differences in age and body mass index between the two groups. Also, the measures of BPS/IC symptoms (ICSI) and associated daily life disruptions (ICPI) were significantly increased in the OSA group when compared to controls.

With the rise in gestational diabetes and metabolic disorders during pregnancy, metformin is also being prescribed more frequently. Although it is known that the oral antidiabetic agent can cross the placental barrier, the impacts on the brain development of the child are largely unknown. An interdisciplinary research team from the German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE) have now been able to demonstrate in a mouse model that although metformin has positive effects in pregnant animals, it does not in the offspring. The results were published in the specialist journal Molecular Metabolism.

Current figures show that around one in six pregnant women worldwide are affected by a special form of diabetes known as gestational diabetes. According to the Robert Koch Institute, 63,000 women in Germany were affected by the disease in 2021, and the trend is increasing.

These numbers are alarming because excessively high blood sugar levels during pregnancy are associated with negative consequences for mother and child. This increases the risk of affected women developing type 2 diabetes later on and their children have a higher risk of developing metabolic disorders and being overweight.