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Epigenetic and social factors both predict aging and health, but new research suggests one might be stronger

Can we objectively tell how fast we are aging? With a good measure, scientists might be able to change our rate of aging to live longer and healthier lives. Researchers know that some people age faster than others and have been trying to concisely measure the internal physiological changes that lead to deteriorating health with age.

For years, researchers have been using clinical factors normally collected at physicals, like hypertension, cholesterol and weight, as indicators to predict aging. The idea was that these measures could determine whether someone is a fast or slow ager at any point in their . But more recently, researchers have theorized that there are other biological markers that reflect aging at the molecular and cellular level. This includes modifications to a person’s genetic material itself, or epigenetics.

While each person has a that largely does not change over their lifetime, to their genetic material that occur throughout life can change which genes are turned on or off and lead to more rapid aging. These changes typically involve the addition of methyl groups to DNA and are influenced by social and environmental exposures, such as , smoking, pollution and depression.

The fungus in the HBO series The Last of Us turns humans into zombies. Should you be afraid?

The fungal pathogen that wipes out much of humanity in HBO’s latest series The Last of Us is real, but can the cordyceps fungus actually turn humans into zombies one day?

“It’s highly unlikely because these are organisms that have become really well adapted to infecting ants,” Rebecca Shapiro, assistant professor at University of Guelph’s department of molecular and cellular biology, told Craig Norris, host of CBC Kitchener-Waterloo’s The Morning Edition.

In the television series, the fungus infects the brain of humans and turns them into zombies. In real life, it can only infect ants and other insects in this manner.

Study shows that distinct pyramidal cell types drive different patterns of cortical activity during decision-making

The outer layer of the brain, known as the cortex, is made of different types of neurons. Neuroscience studies suggest that these different neuron types have distinct functions, yet for a long time this was difficult to ascertain, due to the inability to examine and manipulate them in the brains of living beings.

In recent years, opened new possibilities for studying cells and their functions. Using some of these techniques, researchers at Forschungszentrum Jülich, RWTH Aachen University, Cold Spring Harbor Laboratory and other institutes in the United States closely examined the functions of different pyramidal cells, which are commonly found in the human cortex.

Their findings, published in Nature Neuroscience, suggest that distinct types of pyramidal cells drive patterns of cortical activity associated with different functions. The team’s study builds on some of their previous works focusing on in the cortex.

Brain implant startup backed by Bezos and Gates is testing mind-controlled computing on humans

Synchron’s BCI is inserted through the blood vessels, which Oxley calls the “natural highways” into the brain. Synchron’s stent, called the Stentrode, is fitted with tiny sensors and is delivered to the large vein that sits next to the motor cortex. The Stentrode is connected to an antenna that sits under the skin in the chest and collects raw brain data that it sends out of the body to external devices.

Peter Yoo, senior director of neuroscience at Synchron, said since the device is not inserted directly into the brain tissue, the quality of the brain signal isn’t perfect. But the brain doesn’t like being touched by foreign objects, Yoo said, and the less invasive nature of the procedure makes it more accessible.

“There’s roughly about 2,000 interventionalists who can perform these procedures,” Yoo told CNBC. “It’s a little bit more scalable, compared to, say, open-brain surgery or burr holes, which only neurosurgeons can perform.”

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