New research led by Wen-Sung Chung and Justin Marshall of the University of Queensland is shedding new light on the complexity of squid brains. Using MRI scanning to examine the brain of the of the reef squid Sepioteuthis lessoniana, the researchers have produced a new map of neural connections that improves our understanding of their behavior.

The cephalopods are widely recognized as the most intelligent of mollusks, but how do they rate when they are competing against something other than clams? Cephalopods show all sorts of complex behavior, like being able to recognize patterns, solve problems, communicate through signals, and camouflage themselves in different textures and colors, despite being colorblind.

“We can see that a lot of neural circuits are dedicated to camouflage and visual communication,” says Chung. “Giving the squid a unique ability to evade predators, hunt and conspecific communicate with dynamic color change.”

As they do in many areas of medicine, stem cells hold great potential in treating injured spinal cords, but getting them where they need to go is a delicate undertaking. Scientists at the University of California San Diego (UCSD) are now reporting a breakthrough in this area, demonstrating a new injection technique in mice they say can deliver far larger doses of stem cells and avoid some of the dangers of current approaches.

The research focuses on the use of a type of stem cell known as a neural precursor cell, which can differentiate into different types of neural cells and hold great potential in repairing damaged spines. Currently, these are directly injected into the primary cord of nerve fibers called the spinal parenchyma.

“As such, there is an inherent risk of (further) spinal tissue injury or intraparechymal bleeding,” says Martin Marsala, professor in the Department of Anesthesiology at UCSD School of Medicine.