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Category: neuroscience – Page 649

It can be done. And it can be done sooner than many realise…even within YOUR lifetime. Imagine… Reaching triple digits with the health, fitness and body of an athletic 30 year old… It is entirely within reach now, it may be even less than a decade away. All we need to do is repair the damage that living and our metabolism create, it is slowly accumulating, which is why it takes 7 or 8 decades to rear its ugly head in most people, so one treatment should keep things under control for many years, and by then science will have advanced immeasurably, improving the treatments to whole new levels… Then you can dream of reaching 4 digits…then 5…then 6… BUT You need to stay in good enough shape to last long enough to see the treatments perfected and available. So watch your diet, your mental and physical health, your weight, and look to use occasional fasting, and time restricted eating, along with saunas and cold showers (or any hot/cold therapy), etc., to keep yourself at your optimum until that days arrives. If you want to know more, then this video breaks it down into even more detail. Have a great day and enjoy your journey into the future…

In a roadmap to end aging — understand the hallmarks to change your direction.

Getting old, grey hair, wrinkles, less strength, fragile bones, slower healing… And these are just the visible obvious factors, a slow continual decline towards your final grave. But if you know what is at fault, you can start to make lifestyle changes to alter their trajectory. Watch this video on Stress to find out more about what you can do and why it works https://youtu.be/s17UP_Ia4pQ And we do not only know what is happening, we also have some very good ideas of how to reverse, or at least, slow their decline whilst science works on real solutions. So, this will show you what the problems are, and then we shall start looking at what YOU can do to turn back the clock. With an aging population the benefits of more living their extended years in good health and able to lead whatever lifestyle they desire, is taking on ever more importance. Once you understand the mechanisms and follow the processes you will be able to build a better lifestyle aimed at a long and enjoyable existence. What are you actively doing to extend your healthspan?

Continue reading “Roadmap To End Aging — Understand The Hallmarks To Change Your Direction” | >

Aging research fans might like.

“In their work, Hamiliton’s team found that the Dunkin Hartley guinea pig was a good candidate for a muscle aging model due to the animal’s tendency to develop osteoarthritis (OA) at a young age.”

There are many components to aging, both mental and physical. When it comes to the infrastructure of the human body—the musculoskeletal system that includes muscles, bones, tendons and cartilage—age-associated decline is inevitable, and the rate of that decline increases the older we get. The loss of muscle function—and often muscle mass—is scientifically known as sarcopenia or dynapenia.

For adults in their 40s, sarcopenia is hardly noticeable—about 3% is lost each decade. For those aged 65 years and older, however, can become much more rapid, with an average loss of 1% muscle mass each year. More importantly, sarcopenia is also marked by a decrease in strength, impaired gait, reduced physical activity, or difficulty completing everyday tasks.

Continue reading “Researchers identify promising model for studying human aging” | >

Annotated!

Aubrey David Nicholas Jasper de Grey is an English author and biomedical gerontologist. He is the Chief Science Officer of the SENS Research Foundation and VP of New Technology Discovery at AgeX Therapeutics.
Feel free to ask any related questions that you want Aubrey to try and answer!

Futurist Foundation is a non-profit organization with the goal to connect futurists and promote crowd-sourced projects in science, technology, engineering, mathematics & design.

Continue reading “Aubrey de Grey Longevity Q&A — The last 25 years, SENS, Longevity Escape Velocity, & More” | >

Summary: Pyramidal cells in the CA2 region of the hippocampus are responsible for storing critical timing information.

Source: MIT

When we experience a new event, our brain records a memory of not only what happened, but also the context, including the time and location of the event. A new study from MIT neuroscientists sheds light on how the timing of a memory is encoded in the hippocampus, and suggests that time and space are encoded separately.

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Summary: 20% of glioblastoma brain cancers are fueled by overactive mitochondria. Researchers say these cases may be treatable by drugs currently under trial.

Source: Columbia University.

A new study has found that up to 20% of glioblastomas–an aggressive brain cancer–are fueled by overactive mitochondria and may be treatable with drugs currently in clinical trials.

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For 100 years scientists have disagreed on how to interpret quantum mechanics. A recent study by Jussi Lindgren and Jukka Liukkonen supports an interpretation that is close to classical scientific principles.

Quantum mechanics arose in the 1920s – and since then scientists have disagreed on how best to interpret it. Many interpretations, including the Copenhagen interpretation presented by Niels Bohr and Werner Heisenberg and in particular von Neumann-Wigner interpretation, state that the consciousness of the person conducting the test affects its result. On the other hand, Karl Popper and Albert Einstein thought that an objective reality exists. Erwin Schrödinger put forward the famous thought experiment involving the fate of an unfortunate cat that aimed to describe the imperfections of quantum mechanics.

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Aging is, at least for now, inevitable, and our eyes are not immune to those changes. Vision loss is, in fact, one of the top 10 causes of disability in the US., however, shows that this might be reversible in the future.

A large team of geneticists, ophthalmologists, and other scientists used a group of molecules called Yamanaka factors to turn cells in the eyes of mature mice back to a youthful state. This reversed the damage done by aging, and the cells were then able to regenerate, connect back to the brain, and vision was restored in both models of normal aging and glaucoma.

Yamanaka factors are nothing new in neuroscience. They are named after the after Shinya Yamanaka led research using those factors to convert mature adult cells back to stem cells, kickstarting the field of induced pluripotent stem cells — cells reprogrammed with the ability to generate other types of cells.

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