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Turning Cells Into “Zombies”: Scientists Identify the Secret That Allowed a Parasite To Infect 30% of Humans

A large portion of people on the planet is infected with the parasite Toxoplasma. Now, a study headed by scientists at Stockholm University demonstrates how this tiny parasite spreads so successfully throughout the body, for example to the brain. The parasite infects immune cells and hijacks their identity. The research was recently published in the journal Cell Host & Microbe.

The various roles of immune cells in the body are very strictly regulated in order to combat infections. How Toxoplasma infects so many people and animal species and spreads so quickly has long been a mystery to scientists.

“We have now discovered a protein that the parasite uses to reprogram the immune system”, says Arne ten Hoeve, a researcher at the Department of Molecular Biosciences, Wenner-Gren Institute at Stockholm University.

Scientists Discover a New Daily Rhythm Providing Insight Into How Brain Activity Is Fine-Tuned

Researchers discovered a new daily rhythm in a kind of synapse that dampens brain activity using a mouse model. These neural connections, known as inhibitory synapses, are rebalanced as we sleep to allow us to consolidate new information into lasting memories. The results, which were published in the journal PLOS Biology, may help explain how subtle synaptic changes improve memory in humans. Researchers from the National Institute of Neurological Disorders and Stroke (NINDS), which is part of the National Institutes of Health, led the study.

“Inhibition is important for every aspect of brain function. But for over two decades, most sleep studies have focused on understanding excitatory synapses,” said Dr. Wei Lu, senior investigator at NINDS. “This is a timely study to try to understand how sleep and wakefulness regulate the plasticity of inhibitory synapses.”

Kunwei Wu, Ph.D., a postdoctoral fellow in Dr. Lu’s lab, investigated what occurs at inhibitory synapses in mice during sleep and wakefulness. Electrical recordings from neurons in the hippocampus, a brain region involved in memory formation, revealed a previously unknown pattern of activity. During wakefulness, steady “tonic” inhibitory activity increased but fast “phasic” inhibition decreased. They also discovered a far larger activity-dependent enhancement of inhibitory electrical responses in awake mouse neurons, suggesting that wakefulness, rather than sleep, might strengthen these synapses to a greater extent.

The age of singularity

Will there ever be a time when the human brain and its cognitive abilities will be replaced by a computer.

Can the forms of calculations that are found in a computer be able to go beyond the capacity of the neurons that are found in our own brains.

The age of singularity is where the human brain will be replaced by computers people like elon musk & Ray Kurzweil believe because of technology the future will be a heaven like civilization.

#singularity #technology #science #sciencefacts

Are brain implants the future of computing?

Imagine brain implants that let you control devices by thought alone—or let computers read your mind. It’s early days, but research into this technology is well under way.

Film supported by @mishcondereya.

00:00 — Are brain implants the future of computing?
00:58 — Headsets are changing how brains interact with the virtual world.
02:24 — What is a brain computer interface?
03:24 — What’s holding this technology back?
04:00 — How wearable BCIs can read your mind.
06:27 — How BCIs physically alter the brain.
07:17 — Invasive brain implants.
09:14 — The first human cyborg.
09:51 — What’s next?

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Read our Technology Quarterly on fixing the brain: https://econ.st/3rTay7o.

What does a brain-computer interface feel like? https://econ.st/3z07haD

Communication Breakdown in the Brain

Seizures come suddenly, triggered by stress, fever, flashing lights, or even just feeling tired. Some cause the body to jerk and shake while others can produce strange sensations, make one lose a sense of awareness, or faint. They can happen when the person is awake or asleep. When they pass, after a few seconds or minutes, they leave people tired, confused, and disoriented.

The brain usually maintains a certain level of inhibition that keeps neurons from firing uncontrollably. But during a seizure, one part of the brain starts firing too frantically and can’t stop, resulting in a spike of electrical activity and a seizure.

Stentrode brain computer interface online in first two human patients

Synchron, a neurovascular bioelectronics medicine company, today announced publication of a first-in-human study demonstrating successful use of the Stentrode™ brain-computer interface (BCI), or neuroprosthesis. Specifically, the study shows the Stentrode’s ability to enable patients with severe paralysis to resume daily tasks, including texting, emailing, shopping and banking online, through direct thought, and without the need for open brain surgery. The study is the first to demonstrate that a BCI implanted via the patient’s blood vessels is able to restore the transmission of brain impulses out of the body, and did so wirelessly. The patients were able to use their impulses to control digital devices without the need for a touchscreen, mouse, keyboard or voice activation technology. This feasibility study was published in the Journal of NeuroInterventional Surgery (JNIS), the leading international peer-review journal for the clinical field of neurointerventional surgery, and official journal of the Society of NeuroInterventional Surgery (SNIS).

Keep Forgetting Things? Neuroscience Says These 8 Brain Habits Improve Memory and Leadership

Fortunately, neuroscience can help — both to reassure you that you’re normal, and to provide support for the idea that there are specific habits and practices people can learn in order to improve memory when they need it most. Here are 8 of the most interesting I’ve found over the last couple of years:

Let’s start with this one, because it’s oh-so-easy. Michigan State University researchers studied whether Nile grass rats exhibited better memory when they were kept in an environment where the lighting resembled a corporate office (think dim fluorescent lighting), or where the lighting resembled a sunny day outside.

Sure enough, the study found that rats in dim lighting “lost about 30 percent of capacity in the hippocampus, a critical brain region for learning and memory, and performed poorly on a spatial task they had trained on previously.”

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