Annotated!
Aubrey David Nicholas Jasper de Grey is an English author and biomedical gerontologist. He is the Chief Science Officer of the SENS Research Foundation and VP of New Technology Discovery at AgeX Therapeutics.
Feel free to ask any related questions that you want Aubrey to try and answer!
Futurist Foundation is a non-profit organization with the goal to connect futurists and promote crowd-sourced projects in science, technology, engineering, mathematics & design.
(MS) has been announced by a collaboration including BioNTech, with a study in mice showing great promise for improving symptoms and stopping disease progression.
Summary: Pyramidal cells in the CA2 region of the hippocampus are responsible for storing critical timing information.
Source: MIT
When we experience a new event, our brain records a memory of not only what happened, but also the context, including the time and location of the event. A new study from MIT neuroscientists sheds light on how the timing of a memory is encoded in the hippocampus, and suggests that time and space are encoded separately.
Circa 2017 o.o
The trial plans to inject stem cells into the spinal cords of people declared clinically brain dead, with the ultimate goal of restarting brain activity.
Summary: 20% of glioblastoma brain cancers are fueled by overactive mitochondria. Researchers say these cases may be treatable by drugs currently under trial.
Source: Columbia University.
A new study has found that up to 20% of glioblastomas–an aggressive brain cancer–are fueled by overactive mitochondria and may be treatable with drugs currently in clinical trials.
For 100 years scientists have disagreed on how to interpret quantum mechanics. A recent study by Jussi Lindgren and Jukka Liukkonen supports an interpretation that is close to classical scientific principles.
Quantum mechanics arose in the 1920s – and since then scientists have disagreed on how best to interpret it. Many interpretations, including the Copenhagen interpretation presented by Niels Bohr and Werner Heisenberg and in particular von Neumann-Wigner interpretation, state that the consciousness of the person conducting the test affects its result. On the other hand, Karl Popper and Albert Einstein thought that an objective reality exists. Erwin Schrödinger put forward the famous thought experiment involving the fate of an unfortunate cat that aimed to describe the imperfections of quantum mechanics.
Aging is, at least for now, inevitable, and our eyes are not immune to those changes. Vision loss is, in fact, one of the top 10 causes of disability in the US., however, shows that this might be reversible in the future.
A large team of geneticists, ophthalmologists, and other scientists used a group of molecules called Yamanaka factors to turn cells in the eyes of mature mice back to a youthful state. This reversed the damage done by aging, and the cells were then able to regenerate, connect back to the brain, and vision was restored in both models of normal aging and glaucoma.
Yamanaka factors are nothing new in neuroscience. They are named after the after Shinya Yamanaka led research using those factors to convert mature adult cells back to stem cells, kickstarting the field of induced pluripotent stem cells — cells reprogrammed with the ability to generate other types of cells.
Alzheimer’s Disease (AD) is probably more diverse than our traditional models suggest.
Postmortem, RNA sequencing has revealed three major molecular subtypes of the disease, each of which presents differently in the brain and which holds a unique genetic risk.
Such knowledge could help us predict who is most vulnerable to each subtype, how their disease might progress and what treatments might suit them best, potentially leading to better outcomes.
Moonshot Thinking For Aging, Mental Health, And Drug Re-Purposing — Dr. Tim R. Peterson.
Washington University in St. Louis.
Dr. Tim R. Peterson PhD. is Assistant Professor, in the Department of Medicine, at Washington University in St. Louis.
Summary: The genetics of neurocognitive skills were associated with higher tolerance of risk, delayed fertility, less healthy-risk behavior, and a greater willingness to forgo immediate gratification.
Source: Columbia University.
Noncognitive skills and cognitive abilities are both important contributors to educational attainment — the number of years of formal schooling that a person completes — and lead to success across the life course, according to a new study from an international team led by researchers at Columbia University Mailman School of Public Health, the University of Texas at Austin, and Vrije Universiteit Amsterdam.
