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Category: neuroscience – Page 408

Brain Communicates in Analog and Digital Modes Simultaneously

New Haven, Conn. — Contrary to popular belief, brain cells use a mix of analog and digital coding at the same time to communicate efficiently, according to a study by Yale School of Medicine researchers published this week in Nature.

This finding partially overturns a longstanding belief that each of the brain’s 100 billion neurons communicate strictly by a digital code. Analog systems represent signals continuously, while digital systems represent signals in the timing of pulses. Traditionally, many human-designed circuits operate exclusively in analog or in digital modes.

“This study reveals that the brain is very sophisticated in its operation, using a code that is more efficient than previously appreciated,” said David McCormick, professor in the Department of Neurobiology and senior author of the study. “This has widespread implications, not only for our basic understanding of how the brain operates, but also in our understanding of neuronal dysfunction.”

Brain communicates in both digital and analog

Unlike computers, cells in the brain use digital and analog signals at the same time to communicate with each other, researchers have found.

The finding contradicts the belief that nerve cells in the brain communicate with each other using digital code only.

In an analog system, signals can vary continuously, while digital systems represent signals by a series of pulses. The brain uses a mixture of the two to transmit signals among cells, researchers say.

Decoding Emotions: Beyond Senses in the Human Brain

Summary: A new study explores how the human brain constructs emotions, regardless of sensory input.

By analyzing brain activity in individuals with and without sensory deprivations while they experienced the film 101 Dalmatians, researchers discovered that emotions are represented in the brain through an abstract coding system that transcends sensory modalities. This system involves a distributed network, including the ventromedial prefrontal cortex, which stores abstract representations of emotions.

The findings challenge traditional views on emotion and perception, suggesting that our emotional experiences are not solely dictated by our immediate sensory input but are instead constructed by the brain in a more abstract manner.

Exploring the Past, Present, and Future of Brain Organoids

ABOVE: After years of research, brain organoids now come close to mimicking endogenous brain cells. © iStock, StockSnap.

As a developmental neurobiologist at Harvard University, Paola Arlotta spends most of her time thinking about how the brain develops, how it functions, and what goes wrong in the context of neurological disease. Using human brain organoids as a model for brain development and disease research has been a game changer, providing Arlotta a novel view into brain pathologies that form in utero.

Your brain in the zone: A new neuroimaging study reveals how the brain achieves a creative flow state

The University of Chicago Medicine is among the first 30 institutions in the country to offer tumor-infiltrating lymphocyte (TIL) therapy for advanced melanoma, immediately activating as an authorized treatment center after federal regulators approved the treatment on February 16, 2024.

Effortless, enjoyable productivity is a state of consciousness prized and sought after by people in business, the arts, research, education and anyone else who wants to produce a stream of creative ideas and products. That’s the flow, or the sense of being “in the zone.” A new neuroimaging study from Drexel University’s Creativity Research Lab is the first to reveal how the brain gets to the creative flow state.

The study is published in the journal Neuropsychologia.

The study isolated flow-related brain activity during a creative task: jazz improvisation. The findings reveal that the creative flow state involves two key factors: extensive experience, which leads to a network of brain areas specialized for generating the desired type of ideas, plus the release of control— letting go—to allow this network to work with little or no conscious supervision.

Introducing the next generation of Claude

Anthropic announces Claude 3

The three state-of-the-art models.

Claude 3 opus, claude 3 sonnet, and claude 3 haiku.

Today, we’re announcing the Claude 3 model family, which sets new industry benchmarks across a wide range of cognitive tasks. The family includes three state-of-the-art models in ascending order of capability: Claude 3 Haiku, Claude 3 Sonnet, and Claude 3 Opus.

Exposure to different kinds of music influences how the brain interprets rhythm

When listening to music, the human brain appears to be biased toward hearing and producing rhythms composed of simple integer ratios—for example, a series of four beats separated by equal time intervals (forming a 1:1:1 ratio).

However, the favored ratios can vary greatly between different societies, according to a large-scale study led by researchers at MIT and the Max Planck Institute for Empirical Aesthetics and carried out in 15 countries. The study included 39 groups of participants, many of whom came from societies whose traditional contains distinctive patterns of rhythm not found in Western music.

“Our study provides the clearest evidence yet for some degree of universality in music perception and cognition, in the sense that every single group of participants that was tested exhibits biases for integer ratios. It also provides a glimpse of the variation that can occur across cultures, which can be quite substantial,” says Nori Jacoby, the study’s lead author and a former MIT postdoc, who is now a research group leader at the Max Planck Institute for Empirical Aesthetics in Frankfurt, Germany.

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