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“SuperAgers” Show Cognitive Decline Is Not an Inevitable Part of Aging

For 25 years, scientists at Northwestern Medicine have been studying people aged 80 years and older – dubbed “SuperAgers” – to uncover what makes them stand out.

In a new study, researchers show that these individuals display memory performance comparable to those at least 30 years younger, defying the long-held belief that cognitive decline is an unavoidable part of aging.

The study was published in Alzheimer’s & Dementia.

New insights into how the visual system synchronizes visual information

The human brain builds mental representations of the world based on the signals and information detected via the human senses. While we perceive simultaneously occurring sensory stimuli as being synchronized, the generation and transmission speeds of individual sensory signals can vary greatly.

Researchers at the Institute of Molecular and Clinical Ophthalmology Basel (IOB), University of Basel and Eidgenossische Technische Hochschule (ETH) Zurich recently carried out a study aimed at better understanding how the human visual system achieves this synchronization, regardless of the speed at which visual signals travel. Their paper, published in Nature Neuroscience, reports a previously unknown mechanism through which the retina synchronizes the arrival times of different visual signals.

“We can see because photoreceptors in the retina at the back of our eyes detect light and encode information about the visual world in the form of electrical signals,” Felix Franke and Annalisa Bucci, senior author and first author of the paper, respectively, told Medical Xpress.

Men and Women Reflect on Their Mistakes Differently, Study Finds

Female brains process past mistakes differently, shaped by a specific RNA. This could explain sex-based differences in depression risk and decision-making. A type of RNA that has historically received little attention has now been found to play a key role in building resilience to depression—but

80-year-old ‘SuperAger’ brain operates like that of a 50-year-old. Here’s why

The human brain shrinks as it ages, affecting the ability to remember — it’s part of life. Yet there are a lucky few, called “SuperAgers,” who possess a brain that fights back.


Why does the brain of some people stay sharp into their 80s and beyond? An expert explains what 25 years of exploring the brain tissue of “SuperAgers” has discovered.

Hypoxia ameliorates neurodegeneration and movement disorder in a mouse model of Parkinson’s disease

Parkinson’s disease (PD) involves toxic protein buildup and energy failure in neurons. Continuously breathing low-oxygen air protected mice from PD-like neuronal loss and reversed symptoms, even after they began, suggesting that hypoxia may protect neurons.

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