Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: neuroscience – Page 1,099

African trypanosomiasis is called ‘sleeping sickness’ because when the infection is untreated, trypanosome parasites will invade the brain and cause disruption of sleeping patterns and irreversible neurological damage. A study published on February 25th in PLOS Pathogens reports that in a mouse model of trypanosome disease, nitric oxide (NO) plays an unexpected role in preserving the integrity of the blood brain barrier (BBB), thereby reducing parasite invasion into the brain, and likely limiting neurological damage.

NO is generally thought to be a pro-inflammatory signal, promoting a strong immune response against pathogens. The resulting inflammation is a mixed blessing: on one hand, it helps to control potentially dangerous pathogens, but on the other, it can cause “collateral damage” to the inflamed tissue.

Martin Rottenberg and colleagues, from the Karolinska Institute in Stockholm, Sweden, are interested in how trypanosome cause disease and in the host immune defense against them. In this study, they examine the role of NO in a of trypanosomiasis, with a focus on how the parasites manage to get through the so-called (BBB), the border surrounding the mammalian that is normally impenetrable to foreign intruders as well as most host cells.

Read more

Interesting research and maybe a new twist for Dystonia.

Exactly what triggers dystonia — an involuntary muscle contraction of the hand, fingers, neck or mouth, which is sometimes very painful — is unclear. But some researchers think the underlying problem that causes it may also be the key to treating it, and other brain-linked disorders like Parkinson’s.

Read more

Fifteen miles away from where Larry Page and Sergey Brin worked out of their first office developing the technology that would become Google, a team of eleven engineers no older than 20 are hard at work on developing what they hope will be its replacement.

Their adoptive home, for the moment, is the co-working space Tim Draper set up as part of his Draper University startup program, and they’ve been assembled their by Jerry Yue, a 24-year-old serial entrepreneur.

Yue’s last startup, the Chinese food delivery service Benlai.com, raised $100 million at the end of last year and is on its way to joining the ranks of China’s unicorns.

Read more

Just Amazing

Ralph Mobbs, a neurosurgeon at the Prince of Wales Hospital in Sydney, made medical history in late 2015 when he successfully replaced two vertebrae with custom made prosthesis. The patient, in his 60s, suffered from Chordoma, a particularly nasty form of cancer that had formed on his top two vertebrae and threatened to cinch off his spinal cord as it grew. That would have left him a quadriplegic. Complicating matters, those top two vertebrae are what allow you to turn and tilt your head, so it’s not like doctors can easily fashion a replacement out of bone grafted from another part of the patient’s body. They have to fit perfectly and that’s where the 3D printers come in.

Mobbs worked with Anatomics, an Australian medical device manufacturer, to craft perfect replicas of the patient’s top two vertebrae out of titanium. This is the first time that these two particular neck bones have been printed and installed. “To be able to get the printed implant that you know will fit perfectly because you’ve already done the operation on a model … It was just a pure delight,” Mobbs told Mashable Australia. “It was as if someone had switched on a light and said ‘crikey, if this isn’t the future, well then I don’t know what is’.”

The surgery itself was no small feat. The 15-hour procedure is fraught with peril as the medical team operates within inches of the top of the spinal cord as well as the brainstem and numerous major arteries. “The surgery that we’re doing today is a particularly complicated and long and difficult surgery. It involves exposure at the top of the neck where the neck and the head meets,” Mobbs told ABC 7.30. “It’s essentially disattaching the patient’s head from his neck and taking the tumour out and reattaching his head back onto his neck.” Thankfully, the surgery was a success. Mobbs was able to remove the tumor and implant the prosthetic.

Read more

Interesting read; however, the author has limited his view to Quantum being only a computing solution when in fact it is much more. Quantum technology does offer faster processing power & better security; but, Quantum offers us Q-Dots which enables us to enrich medicines & other treatments, improves raw materials including fuels, even vegetation.

For the first time we have a science that cuts across all areas of technology, medical & biology, chemistry, manufacturing, etc. No other science has been able to achieve this like Quantum.

Also, the author in statements around being years off has some truth if we’re suggesting 7 yrs then I agree. However, more than 7 years I don’t agree especially with the results we are seeing in Quantum Networking.

Not sure of the author’s own inclusion on some of the Quantum Technology or Q-Dot experiements; however, I do suggest that he should look at Quantum with a broader lens because there is a larger story around Quantum especially in the longer term as well look to improve things like BMI, AI, longevity, resistent materials for space, etc/.

I recently read Seth Lloyd’s A Turing Test for Free Will — conveniently related to the subject of the blog’s last piece, and absolutely engrossing. It’s short, yet it makes a wonderful nuance in the debate over determinism, arguing that predictable functions can still have unpredictable outcomes, known as “free will functions.”

I had thought that the world only needed more funding, organized effort, and goodwill to solve its biggest threats concerning all of humanity, from molecular interactions in fatal diseases to accessible, accurate weather prediction for farmers. But therein lies the rub: to be able to tackle large-scale problems, we must be able to analyze all the data points associated to find meaningful recourses in our efforts. Call it Silicon Valley marketing, but data analysis is important, and fast ways of understanding that data could be the key to faster solution implementation.

Continue reading “Quantum Algorithms and Their Discontents” | >

How our brains view beauty is also from heredity.

British neurobiologist Semir Zeki says human brains work alike and we have a shared inheritance in the way we perceive beauty Who do you think is beautiful? Apparently all our votes would more or less go to the same person. Wherever we are from in the world, man or woman, Indian or South American, the way we experience beauty is pretty much the same. Because our brains work similarly, and as humans, we have a shared inheritance. Listening to British neurobiologist Semir Zeki is sure to leave one mesmerised about our understanding of the way our brains work.

Zeki, a frontrunner in the fairly nascent field of neuro-aesthetics, was in Bengaluru recently for the British Council’s lecture series “Science and Beyond”. A professor of neuro-aesthetics at the University College London, Zeki specialises in studying the primate visual brain, neural correlates of the experience of love, desire, beauty, within the field of neuro-aesthetics. In his award-winning study conducted across people of various races and cultures, the question he addressed was ‘What are the neural mechanisms that are engaged when you experience beauty?’. “I have not asked anything about the concept of beauty, the nature of beauty or anything like that. All I can tell you is that when you experience beauty, regardless of the source – whether it is visual, musical or mathematical, its correlated activity is in the same part of the brain.

Source: http://www.thehindu.com/features/metroplus/beauty-and-the-br…276239.ece

Read more

MindMaze has received $100 million to further medical research and launch a VR gaming system.

For a soldier who has endured an amputation, severe phantom limb pain can be debilitating.

Virtual reality company MindMaze has designed a medical virtual reality, augmented reality, and motion capture video game system that immerses the amputee in a virtual environment, where moving the existing arm will move the non-existing arm of the avatar. Neuroscientist and MindMaze founder and CEO Tej Tadi says this “mirroring” tricks the brain into believing the severed limb is actually there, and has proven benefits in phantom pain management.

Read more