Lifeboat Foundation

Northwestern investigators have demonstrated that fine-tuning DNA interaction strength can improve colloidal crystal engineering to enhance their use in creating an array of functional nanomaterials, according to a recent study published in ACS Nano.

Chad Mirkin, Ph.D., professor of Medicine in the Division of Hematology and Oncology, the George B. Rathmann Professor of Chemistry at Northwestern’s Weinberg College of Arts and Sciences, and director of the International Institute for Nanotechnology, was senior author of the study.

Colloidal crystal engineering with DNA involves modifying nanoparticles into programmable atom equivalents, or “PAEs,” which are used to form colloidal crystals that can then be used for designing programmable, synthetic DNA sequences.

How can Marvel movie character Ant-Man produce such strong energy out of his small body? The secret lies in the transistors on his suit that amplify weak signals for processing. Transistors that amplify electrical signals in the conventional way lose heat energy and limit the speed of signal transfer, which degrades performance. What if it were possible to overcome such limitations and make a high-performance suit that is light and small but without the loss of heat energy?

A POSTECH team of Professor Kyoung-Duck Park and Yeonjeong Koo from the Department of Physics and a team from ITMO University in Russia led by Professor Vasily Kravtsov jointly developed a nano-excitonic transistor using intralayer and interlayer excitons in heterostructure-based semiconductors, which addresses the limitations of existing transistors. The research was recently published in the journal ACS Nano.

Excitons are responsible for light emission of semiconductor materials and are key to developing a next-generation light-emitting element with less heat generation and a light source for quantum information technology due to the free conversion between light and material in their electrically neutral states.

For two decades, physicists have tried to directly manipulate the spin of electrons in 2D materials like graphene. Doing so could spark key advances in the burgeoning world of 2D electronics, a field where super-fast, small and flexible electronic devices carry out computations based on quantum mechanics.

Standing in the way is that the typical way in which scientists measure the spin of electrons—an essential behavior that gives everything in the physical universe its structure—usually doesn’t work in 2D materials. This makes it incredibly difficult to fully understand the materials and propel forward technological advances based on them. But a team of scientists led by Brown University researchers believe they now have a way around this longstanding challenge. They describe their solution in a new study published in Nature Physics.

In the study, the team—which also include scientists from the Center for Integrated Nanotechnologies at Sandia National Laboratories, and the University of Innsbruck—describe what they believe to be the first measurement showing direct interaction between electrons spinning in a 2D material and photons coming from microwave radiation.

The early detection and treatment of dementia such as Alzheimer’s is still one of the great challenges of modern medicine. It is already known that certain proteins in the cerebrospinal fluid can be used to diagnose Alzheimer’s disease. However, the current detection methods for such biomarkers by means of biochemical tests can only confirm and quantify the presence of such pathological proteins. No conclusions can be drawn about their original morphology of the proteins using biochemical assays, which holds information on disease stages.

However, such information if obtained directly in a label-free manner could allow conclusions to be drawn about the stage of the disease and evaluate the efficiency of a prescribed treatment. A team from the Transport at Nanoscale Interfaces Laboratory at Empa and the Department of Neurology at the Cantonal Hospital in St. Gallen has now used atomic force microscopy (AFM) to visualize the proteins that are indicative of Alzheimer’s disease under conditions that are as close to reality as possible. The researchers recently published their results in the journal Communications Biology.

With the new study, the researchers add another piece of the puzzle to their insights into Alzheimer’s development and diagnosis.

Scientists have uncovered the inner workings of one of the most important and intricate “nanobots” operating within our cells by using cutting-edge microscopy for visualizing molecules almost at an atomic level.

Their new study published in Nature has unveiled the critical step that switches on the spliceosome —a piece of cellular machinery that enables cells to build complex proteins.

By uncovering in detail how the spliceosome is activated, scientists believe the discovery could pave the way to more effective designs for cancer drugs that target it.

Year 2020 😗😁

Schizophrenia is one of the top 25 causes of global diseases burdens in terms of years lived with the disease and the emotional and economical strains it imposes on the society. Several strategies have been used to treat the patients, specially using typical and atypical psychoactives. However, due to its multifactorial characteristic and patient resistance, schizophrenia is still a difficult disease to diagnose and treat. Thus, new strategies for diagnostics and treatment must be researched to optimize the efficacy and reduce the side effects of the actual therapy. Nanomedicine tries to improve low-weight molecular agents for treatment of diseases through the use of nanoscaled carriers. Among nanomedicine, nanopsychiatry specifically deals with the potential role of nanotechnology in solving psychiatry diseases problems. Therefore, the objective of this work is to provide an overview of the state of the art of nanopsychiatry in the sense of treating schizophrenia.

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Root canal treatment removes the infection and bacteria from the core of a tooth — the pulp chamber. These bacteria are often present within the canals of the teeth. However, proper treatment saves a badly infected natural tooth from needing to be extracted. Sufficient cleaning of the root canals is a key step of RCT. A lack of proper canal debridement can cause bacteria to thrive — a significant cause of RCT failures.

The tooth is washed with antibiotics or other chemicals that kill the bacteria to get rid of the infection. However, some teeth have complex root structures, and conventional ways of cleaning them are not enough to remove all bacteria. That’s one area where dental nanorobots can help. Nanorobots are showing promise in different steps of RCT, even better than traditional ways.

Continue reading “Dental Nanorobots: An Innovation to Improve Root Canal Treatment” »

A time crystal, as originally proposed in 2012, is a new state of matter in which the particles are in continuous oscillatory motion. Time crystals break time-translation symmetry. Discrete time crystals do so by oscillating under the influence of a periodic external parametric force, and this type of time crystal has been demonstrated in trapped ions, atoms and spin systems.

Continuous time crystals are more interesting and arguably more important, as they exhibit continuous time-translation symmetry but can spontaneously enter a regime of periodic motion, induced by a vanishingly small perturbation. It is now understood that this state is only possible in an open system, and a continuous quantum-time-crystal state has recently been observed in a quantum system of ultracold atoms inside an optical cavity illuminated with light.

In a paper published in Nature Physics, researchers at University of Southampton in the U.K. showed that a classical metamaterial nanostructure can be driven to a state that exhibits the same key characteristics of a continuous time crystal.

A proposed technique would use light and nanowires to generate electron beams with nearly pure spin polarization.

In a polarized electron beam, the particles’ spins are not randomly oriented but favor a particular direction. The polarization serves as a useful property for studying the magnetism of materials or for probing the spins of atoms or nuclei. But such a beam typically has a low degree of polarization unless it is produced at a synchrotron facility. Theorists have proposed creating these beams using laser light, but so far these approaches have involved extremely intense lasers and have not been expected to produce high polarization. Now Deng Pan of East China Normal University and Hongxing Xu of Wuhan University, China, have proposed a method that reduces the required laser intensity by up to 10 billion times compared with previous laser-based approaches and that should produce a pair of beams that are nearly 100% polarized [1].

In Pan and Xu’s proposal, a wide laser beam broadsides an array of parallel conducting nanowires with 100-nm spacing and excites them to emit electromagnetic waves. An unpolarized electron beam is sent across the array, perpendicular to the wires, about 100 nm away from them. Some electrons absorb or emit photons, causing their spins to align parallel or antiparallel to the local electric field. They also gain or lose a photon’s worth of energy. This interaction with the radiation near the wires generates two new beams with nearly pure spin polarizations and slightly different energies, allowing them to be easily separated. Pan and Xu say that the technique should be implementable with current technology and that it may even lead to new ways of manipulating electrons.