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The body is pretty good at repairing itself, but some parts of our anatomy struggle to bounce back after an injury.

One such material is cartilage – the spongy yet firm connective tissue that keeps our bones from rubbing and jarring against each other. Over time, the translucent or ‘hyaline’ components of cartilage can become heavily degraded, resulting in painful conditions like osteoarthritis and chondromalacia.

Scientists have been working on a way to regenerate hyaline cartilage for years, and now a team led by Northwestern University in the US has achieved a breakthrough. They have developed a biomaterial that, injected into damaged cartilage in living sheep, acted as a scaffold that promoted cartilage regrowth in active joints.

How do astronauts cope with life onboard the International Space Station (ISS) and how can scientists study it? This is what a recent study published in PLoS ONE hopes to address as an international team of researchers used archaeological investigation strategies to ascertain how ISS crew members managed their lives in space, specifically pertaining to the astronauts’ habits of using and storing the various materials onboard the orbiting outpost. This study holds the potential to help scientists better understand how humans cope with living in space for long periods of time, which could be useful for trips to the Moon and Mars, someday.

The study, known as the Sampling Quadrangle Assemblages Research Experiment (SQuARE) experiment, was conducted over a 60-day period between January and March 2022 where six common locations onboard the ISS were designated as “squares”, which is a common archaeology strategy of digging pits to ascertain the most viable areas of further investigation. During the study, the astronauts photographed each square every day to ascertain how they were used, and the researchers would compare that to the location’s original purpose.

Helical foldamers are a class of artificial molecules that fold into well-defined helical structures like helices found in proteins and nucleic acids. They have garnered considerable attention as stimuli-responsive switchable molecules, tuneable chiral materials, and cooperative supramolecular systems due to their chiral and conformational switching properties.

Double-helical foldamers exhibit not only even stronger chiral properties but also , such as the transcription of chiral information from one chiral strand to another without chiral properties, enabling potential applications in higher-order structural control related to replication, like nucleic acids.

However, the artificial control of the chiral switching properties of such artificial molecules remains challenging due to the difficulty in balancing the dynamic properties required for switching and stability. Although various helical molecules have been developed in the past, reversal of twist direction in double-helix molecules and supramolecules has rarely been reported.

Heat and pressure can deteriorate the properties of piezoelectric materials that make state-of-the-art ultrasound and sonar technologies possible – and fixing that damage has historically required disassembling devices and exposing the materials to even higher temperatures. Now researchers have developed a technique to restore those properties at room temperature, making it easier to repair these devices – and paving the way for new ultrasound technologies.

Piezoelectric materials have many applications, including sonar technologies and devices that generate and sense ultrasound waves. But for these devices to efficiently generate sonar or ultrasound waves, the material needs to be “poled.”

That’s because the piezoelectric materials used for sonar and ultrasound applications are mostly ferroelectric. And like all ferroelectric materials, they exhibit a phenomenon called spontaneous polarization. That means they contain pairs of positively and negatively charged ions called dipoles. When a ferroelectric material is poled, that means all of its dipoles have been pulled into alignment with an external electric field. In other words, the dipoles are all oriented in the same direction, which makes their piezoelectric properties more pronounced.