Lifeboat Foundation: Safeguarding Humanity
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Category: lifeboat – Page 18

Planning for First Lifeboat Foundation Conference Underway

Planning for the first Lifeboat Foundation conference has begun. This FREE conference will be held in Second Life to keep costs down and ensure that you won’t have to worry about missing work or school.

While an exact date has not yet been set, we intend to offer you an exciting line up of speakers on a day in the late spring or early summer of 2008.

Several members of Lifeboat’s Scientific Advisory Board (SAB) have already expressed interest in presenting. However, potential speakers need not be Lifeboat Foundation members.

If you’re interested in speaking, want to help, or you just want to learn more, please contact me at [email protected].

Help Develop the NanoShield

What’s the NanoShield you ask? It’s a long-term scientific research project aimed at creating a nanotechnoloigical immune system. You can learn more about it here.

Facebook users — please come join the cause and help fund the Lifeboat Foundation’s NanoShield project.

Not a Facebook user? No worries. By joining the Lifeboat Foundation and making even a small donation you can have a hugely positive impact on humanity’s future well being.

So why not join us?

Helphookup.com internet empowered volunteers against disasters

The inspiration of Help Hookup is actually a comic book called Global Frequency by Warren Ellis. My brother, Alvin Wang, took the idea to startup weekend and they launched the idea this past weekend for hooking up volunteers. It is similar to the concepts of David Brin’s “empowered citizens” and Glenn Reynolds “an army of Davids”. The concepts are compatible with the ideas and causes of the Lifeboat foundation.

Global Frequency was a network of 1,001 people that handled the jobs that the governments did not have the will to handle. I thought that it was a great idea and it would be more powerful with 1,000,001 people or 100,000,001 people. We would have to leave out the killing that was in the comic.

Typhoons, earthquakes, and improperly funded education could all be handled. If there is a disaster, doctors could volunteer. Airlines could provide tickets. Corporations could provide supples. Trucking companies could provide transportation. Etc. State a need, meet the need. No overhead. No waste.

The main site is here it is a way for volunteers to hookup

The helphookup blog is tracking the progress.

One shot Gene therapy protection from radiation

University of Pittsburgh researchers injected a therapy previously found to protect cells from radiation damage into the bone marrow of mice, then dosed them with some 950 roentgens of radiation — nearly twice the amount needed to kill a person in just five hours. Nine in 10 of the therapy-receiving mice survived, compared to 58 percent of the control group.

Between 30 and 330 days, there were no differences in survival rates between experiment and control group mice, indicating that systemic MnSOD-PL treatment was not harmful to survival.

The researchers will need to verify whether this treatment would work in humans.

This is part of the early development in the use of genetic modification to increase the biological defences (shields) of people against nuclear, biological and chemical threats. We may not be able to prevent all attacks, so we should improve our toughness and survivability. We should still try to stop the attacks and create the conditions for less attacks.

Lifeboat Foundation Fellow wins Feynman Prize

Robert Freitas, Jr., Lifeboat Foundation Fellow and head of the Lifeboat Foundation’s Nanomedicine Division has won the 2007 Foresight Institute Feynman Prize in Communication.

Dr. Pearl Chin, President of the Foresight Nanotech Institute, said Freitas received the award for “pioneering the study and communication of the benefits to be obtained from an advanced nanomedicine that will be made possible by molecular manufacturing [and for having] worked to develop and communicate a path from our current technology base to a future technology base that will enable advanced nanomedicine.”

Prior to his Feynman Prize win Robert shared the Lifeboat Foundation’s 2006 Guardian Award with technology legend Bill Joy. Freitas and Joy shared the Guardian award for their many years of work on mitigating risks posed by advanced technologies.

Structure of influenza B virus protein gives clues to next pandemic

Determining the structure of a protein called hemagglutinin on the surface of influenza B is giving researchers at Baylor College of Medicine and Rice University in Houston clues as to what kinds of mutations could spark the next flu pandemic.

This is interesting research and progress in understanding and possibly blocking changes that would lead to pandemics.

In a report that goes online today in the Proceedings of the National Academy of Sciences (PNAS), Drs. Qinghua Wang, assistant professor of biochemistry and molecular biology at BCM, and Jianpeng Ma, associate professor in the same department and their colleagues describe the actual structure of influenza B virus hemagglutinin and compare it to a similar protein on influenza A virus. That comparison may be key to understanding the changes that will have to occur before avian flu (which is a form of influenza A virus) mutates to a form that can easily infect humans, said Ma, who holds a joint appointment at Rice. He and Wang have identified a particular residue or portion of the protein that may play a role in how different types of hemagglutinin bind to human cells.

“What would it take for the bird flu to mutate and start killing people” That’s the next part of our work,” said Ma. Understanding that change may give scientists a handle on how to stymie it.

There are two main forms of influenza virus – A and B. Influenza B virus infects only people while influenza A infects people and birds. In the past, influenza A has been the source of major worldwide epidemics (called pandemics) of flu that have swept the globe, killing millions of people. The most famous of these was the Pandemic of 1918–1919, which is believed to have killed between 20 and 40 million people worldwide. It killed more people than World War I, which directly preceded it.

The Asian flu pandemic of 1957–1958 is believed to have killed as many as 1.5 million people worldwide, and the so-called Hong Kong flu pandemic of 1968–1969 is credited with as many as 1 million deaths. Each scourge was accompanied by a major change in the proteins on the surface of the virus.

The Lifeboat Foundation has the bioshield project

Inflatable Mirrors on spacecraft would move asteroids fastest

New Scientist reports on a new study by researchers led by Massimiliano Vasile of the University of Glasgow in Scotland have compared nine of the many methods proposed to ward off such objects, including blasting them with nuclear explosions.

The team assessed the methods according to three performance criteria: the amount of change each method would make to the asteroid’s orbit, the amount of warning time needed and the mass of the spacecraft needed for the mission.

The method that came out on top was a swarm of mirror-carrying spacecraft. The spacecraft would be launched from Earth to hover near the asteroid and concentrate sunlight onto a point on the asteroid’s surface.

In this way, they would heat the asteroid’s surface to more than 2100° C, enough to start vaporising it. As the gases spewed from the asteroid, they would create a small thrust in the opposite direction, altering the asteroid’s orbit.

The scientists found that 10 of these spacecraft, each bearing a 20-metre-wide inflatable mirror, could deflect a 150-metre asteroid in about six months. With 100 spacecraft, it would take just a few days, once the spacecraft are in position.

To deflect a 20-kilometre asteroid, about the size of the one that wiped out the dinosaurs, it would take the combined work of 5000 mirror spacecraft focusing sunlight on the asteroid for three or more years.

But Clark Chapman of the Southwest Research Institute in Boulder, Colorado, US, says ranking the options based on what gives the largest nudge and takes the least time is wrongheaded.

The proper way to go about ranking this “is to give weight to adequate means to divert an NEO of the most likely sizes we expect to encounter, and to do so in a controllable and safe manner”, Chapman told New Scientist.

The best approach may be to ram the asteroid with a spacecraft to provide most of the change needed, then follow up with a gravity tractor to make any small adjustments needed, he says.

It is good to have several options for deflection and a survey to detect the specific risks of near earth objects.

New field-deployable biosensor detects avian influenza virus in minutes instead of days

A new biosensor developed at the Georgia Tech Research Institute (GTRI) can detect avian influenza in just minutes. In addition to being a rapid test, the biosensor is economical, field-deployable, sensitive to different viral strains and requires no labels or reagents.

This kind of technology could be applied to real time monitoring of other diseases as well.


Photograph of the optical biosensor that is approximately 16 millimeters by 33 millimeters in size. The horizontal purple lines are the channels on the waveguide. Credit: Gary Meek

“We can do real-time monitoring of avian influenza infections on the farm, in live-bird markets or in poultry processing facilities,” said Jie Xu, a research scientist in GTRI’s Electro-Optical Systems Laboratory (EOSL)

The biosensor is coated with antibodies specifically designed to capture a protein located on the surface of the viral particle. For this study, the researchers evaluated the sensitivity of three unique antibodies to detect avian influenza virus.

The sensor utilizes the interference of light waves, a concept called interferometry, to precisely determine how many virus particles attach to the sensor’s surface. More specifically, light from a laser diode is coupled into an optical waveguide through a grating and travels under one sensing channel and one reference channel.

Researchers coat the sensing channel with the specific antibodies and coat the reference channel with non-specific antibodies. Having the reference channel minimizes the impact of non-specific interactions, as well as changes in temperature, pH and mechanical motion. Non-specific binding should occur equally to both the test and reference channels and thus not affect the test results.

An electromagnetic field associated with the light beams extends above the waveguides and is very sensitive to the changes caused by antibody-antigen interactions on the waveguide surface. When a liquid sample passes over the waveguides, any binding that occurs on the top of a waveguide because of viral particle attachment causes water molecules to be displaced. This causes a change in the velocity of the light traveling through the waveguide.

Risks Not Worth Worrying About

There are dozens of published existential risks; there are undoubtedly many more that Nick Bostrom did not think of in his paper on the subject. Ideally, the Lifeboat Foundation and other organizations would identify each of these risks and take action to combat them all, but this simply isn’t realistic. We have a finite budget and a finite number of man-hours to spend on the problem, and our resources aren’t even particularly large compared with other non-profit organizations. If Lifeboat or other organizations are going to take serious action against existential risk, we need to identify the areas where we can do the most good, even at the expense of ignoring other risks. Humans like to totally eliminate risks, but this is a cognitive bias; it does not correspond to the most effective strategy. In general, when assessing existential risks, there are a number of useful heuristics:

- Any risk which has become widely known, or an issue in contemporary politics, will probably be very hard to deal with. Thus, even if it is a legitimate risk, it may be worth putting on the back burner; there’s no point in spending millions of dollars for little gain.

- Any risk which is totally natural (could happen without human intervention), must be highly improbable, as we know we have been on this planet for a hundred thousand years without getting killed off. To estimate the probability of these risks, use Laplace’s Law of Succession.

- Risks which we cannot affect the probability of can be safely ignored. It does us little good to know that there is a 1% chance of doom next Thursday, if we can’t do anything about it.

Some specific risks which can be safely ignored:

- Particle accelerator accidents. We don’t yet know enough high-energy physics to say conclusively that a particle accelerator could never create a true vacuum, stable strangelet, or another universe-destroying particle. Luckily, we don’t have to; cosmic rays have been bombarding us for the past four billion years, with energies a million times higher than anything we can create in an accelerator. If it were possible to annihilate the planet with a high-energy particle collision, it would have happened already.

- The simulation gets shut down. The idea that “the universe is a simulation” is equally good at explaining every outcome- no matter what happens in the universe, you can concoct some reason why the simulators would engineer it. Which specific actions would make the universe safer from being shut down? We have no clue, and barring a revelation from On High, we have no way to find out. If we do try and take action to stop the universe from being shut down, it could just as easily make the risk worse.

- A long list of natural scenarios. To quote Nick Bostrom: “solar flares, supernovae, black hole explosions or mergers, gamma-ray bursts, galactic center outbursts, supervolcanos, loss of biodiversity, buildup of air pollution, gradual loss of human fertility, and various religious doomsday scenarios.” We can’t prevent most of these anyway, even if they were serious risks.

Some specific risks which should be given lower priority:

- Asteroid impact. This is a serious risk, but it still has a fairly low probability, on the order of one in 105 to 107 for something that would threaten the human species within the next century or so. Mitigation is also likely to be quite expensive compared to other risks.

- Global climate change. While this is fairly probable, the impact of it isn’t likely to be severe enough to qualify as an existential risk. The IPCC Fourth Assessement Report has concluded that it is “very likely” that there will be more heat waves and heavy rainfall events, while it is “likely” that there will be more droughts, hurricanes, and extreme high tides; these do not qualify as existential risks, or even anything particularly serious. We know from past temperature data that the Earth can warm by 6–9 C on a fairly short timescale, without causing a permanent collapse or even a mass extinction. Additionally, climate change has become a political problem, making it next to impossible to implement serious measures without a massive effort.

- Nuclear war is a special case, because although we can’t do much to prevent it, we can take action to prepare for it in case it does happen. We don’t even have to think about the best ways to prepare; there are already published, reviewed books detailing what can be done to seek safety in the event of a nuclear catastrophe. I firmly believe that every transhumanist organization should have a contingency plan in the event of nuclear war, economic depression, a conventional WWIII or another political disaster. This planet is too important to let it get blown up because the people saving it were “collateral damage”.

- Terrorism. It may be the bogeyman-of-the-decade, but terrorists are not going to deliberately destroy the Earth; terrorism is a political tool with political goals that require someone to be alive. While terrorists might do something stupid which results in an existential risk, “terrorism” isn’t a special case that we need to separately plan for; a virus, nanoreplicator or UFAI is just as deadly regardless of where it comes from.

Lifeboat Foundation Interview on Betterhumans

Recently, our international spokesperson, Philippe Van Nedervelde, spoke to the deputy editor of Betterhumans, Parish Mozdzierz, on the Lifeboat Foundation, its goals and activities. Here is the first question:

Betterhumans: How did the formation of the Lifeboat Foundation come about?

Philippe Van Nedervelde: Lifeboat Foundation’s founder, Eric Klien, was shaken wide awake by 9/11. The new reality of what we call (exponentially accelerating) “Asymmetric Destructive Capability” (ADC) fully hit him: ever smaller groups of people can create ever more enormous amounts of damage. And all of this thanks to advances in technology. As a bracelet-wearing cryonicist, he knew of the potentials of nanotechnology (having attended MIT Nanotechnology Group meetings in the late 1980s), and that 9/11 was just a taste of things to come. Accordingly, the Lifeboat Foundation was incorporated within months of 9/11.

Read the whole thing here.

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