The drug, LOY-001, works by interacting with a hormone that accelerates aging.
Category: life extension – Page 95
Regenerative medicine might just have had a new tool added to its arsenal: Scientists have created tiny biological robots out of living human cells. Though they may be small, the self-assembling bots are mighty, with a study demonstrating their potential for healing and treating disease.
The team had already proven their biological robotics chops back in 2020 with the creation of Xenobots, made from frog embryonic cells. They even managed to design Xenobots so that they could reproduce in a way that no living animal or plant does, something that had never been seen before.
The researchers weren’t sure whether the incredible capabilities of the Xenobots were in some way down to their amphibious origins, so they wanted to find out if biobots could also be created from the cells of other organisms. And why not begin with humans?
The hypertension drug rilmenidine has been shown to slow down aging in worms, an effect that in humans could hypothetically help us live longer and keep us healthier in our latter years.
Previous research has shown rilmenidine mimics the effects of caloric restriction on a cellular level. Reducing available energy while maintaining nutrition within the body has been shown to extend lifespans in several animal models.
Whether this translates to human biology, or is a potential risk to our health, is a topic of ongoing debate. Finding ways to achieve the same benefits without the costs of extreme calorie cutting could lead to new ways to improve health in old age.
Any team that can restore at least a decade’s worth of muscle, brain, and immune function in older adults will claim the top prize.
Money can’t buy happiness, but X Prize founder Peter Diamandis hopes it might be able to buy better health.
Summary: Researchers developed ‘Anthrobots,’ microscopic biological robots made from human tracheal cells, demonstrating potential in healing and regenerative medicine.
These self-assembling multicellular robots, ranging from hair-width to pencil-point size, show remarkable healing effects, particularly in neuron growth across damaged areas in lab conditions.
Building on earlier Xenobot research, this study reveals that Anthrobots can be created from adult human cells without genetic modification, offering a new approach to patient-specific therapeutic tools.
The new contest aims to spur innovation into longer ‘healthspans’ with treatments that can actually reverse age-related degradation in body, mind and immune system.
XPRIZE has launched the largest prize in history–XPRIZE Healthspan, a competition that will revolutionize the way we approach human aging. In case you missed it, watch our launch event here.
Science: Research suggest that dinosaurs 🦕 🦖 may have influenced how humans age today.
Human aging may have been influenced by millions of years of dinosaur domination according to a new theory from a leading aging expert. The ‘longevity bottleneck’ hypothesis has been proposed by Professor Joao Pedro de Magalhaes from the University of Birmingham in a new study published in BioEssays. The hypothesis connects the role that dinosaurs played over 100 million years with the aging process in mammals.
While some reptiles and amphibians show no significant signs of aging, all mammals—including humans—show a marked aging process.
Professor de Magalhaes’ hypothesis suggests that during the Mesozoic Era, mammals faced persistent pressure for rapid reproduction during the reign of dinosaurs, which over 100 million years led to the loss or inactivation of genes associated with long life, such as processes associated with tissue regeneration and DNA repair.
The FDA has yet to approve any drugs for life extension. But biotech company Loyal is now a step closer to bringing one to market—for dogs.
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