Toggle light / dark theme

Big Data and Genetic Sequencing Will Help Extend the Human Lifespan

Gooooood, good.


Big data will help crack the code on aging.

Two of the leading scientists at the edge of the medical revolution believe that our life expectancy could start creeping up toward the triple digits.

David Agus, a professor of medicine and engineering at the University of Southern California, said at the Fortune Global Forum on Monday that he believes that with our current technology humans have the potential to regularly live into their ninth or tenth decade.

Read more

Cryonics Is No Fantasy, Should We Be Taking It Seriously?

Most science starts off at the fringe and slowly makes it way to the mainstream. Cryopreservation is commonly achieved in a laboratory setting, but for many years serious applications remained confined to science fiction. Is it time to change how we see cryonics?

The science of freezing things

Scientific research requires great storage, and huge amounts of material including cells are frozen every day to be used at the later date. If you follow the correct protocols, many forms of life can be re-awakened after their cryogenic sleep. DMSO, propylene glycol and glycerol help abolish problems like ice crystals which can rupture cells, and storage temperatures can drop to below −120 oC. At these levels biological reactions are essentially halted.

Read more

Russian scientist seeks immortality, injects himself with 3.5-million-year-old bacteria

In the Holy Bible, Jesus Christ taught us how to attain eternal life. In John 6:71, for example, Jesus Christ said: “Truly, truly, I say to you, unless you eat the flesh of the Son of Man and drink his blood, you have no life in you. Whoever feeds on my flesh and drinks my blood has eternal life, and I will raise him up on the last day.”

A Russian scientist, however, believes that he can have eternal life through the power of science, more specifically through the power of 3.5-million-year-old bacteria.

Read more

Sounds Gross, But Intestinal Worms Can Actually Be Good For You

Intestinal worms that can reduce inflammation. Could we GMO a probiotic worm to help reduce aging?


Intestinal worms have an incredibly bad reputation. The thought of them sneaking around inside our bodies and eating us from the inside is pretty unpleasant. But for decades, results coming out of lab after lab have shown that some kinds of helminths can be extremely beneficial to their host, and aren’t parasites at all.

Just 100 years ago, before toilets and running water were commonplace, everybody had regular exposure to intestinal worms. Thanks in part to modern plumbing, people in the industrialized world have now lost almost all of their worms, with the exception of occasional pinworms in some children.

Intestinal worms are properly called “helminths,” which most dictionaries will tell you are parasites. Exploiting their hosts, draining resources, sucking the life out of the body – that’s what parasites do, by definition. Indeed, many helminths, including the porcine tapeworm and the human hookworm, are known to cause disease and even death in the human population. Parasitic worms are still a big problem in some parts of the world.

Read more

Why Focusing On The Obesity Epidemic Distracts Us From The Aging Epidemic

Large amounts of precious resources are being spent on encouraging weight loss and healthy living. While the intention of trying to reinforce healthy living is laudable, the evidence is that our resources are being wasted on minimal benefits.

Society considers obesity a big threat that needs to be overcome, but being thin is seen as a panacea

The diseases caused by biological aging carry on incessantly taking the lives of 100 000 people every day. While age 87 is the most common age of death for people in the western world, little progress has occurred during the past decades.

Read more

The “Age” Age

A very interesting article about the state of funding for aging research and about Buck and ex Geron Mike West.


As I mentioned in last week’s letter, I traveled to San Francisco last Monday with my friend Patrick Cox, who writes our Transformational Technology Alert newsletter. We had dinner with Dr. Mike West of Biotime and then spent the next morning at the Buck Institute for Research on Aging. Pat and I decided we would jointly report on what we learned. He has already written his part, which was published last week. I am going to reproduce portions of that letter, which highlight the conversation with Brian Kennedy and his team at the Buck Institute, and then add my own thoughts about our conversation with Mike West the previous night.

(Note that I am excerpting Patrick’s paid letter, which includes comments on companies in his portfolio, rather than his free weekly Transformational Technologies Tech Digest service. We agreed that it was important to do so in this one case, given the huge significance of the research involved and the Buck Institute’s relationship to it.)

Essentially, we looked at two aspects of aging. The Buck Institute is focused on how to slow down the aging process and reduce the symptoms (such as chronic diseases) that come with aging. Dr. Mike West and his colleagues, as well as a few other firms and researchers, are focused on using our own pluripotent stem cells in ways that would allow us to repair organs in our bodies, thus giving us the opportunity to “grow younger” again. (It’s not quite that simple, as I’ll try to explain later.)

Read more

Edouard: Please take the time to send this to the World Health Organisation tonight if possible or tomorrow

This is our chance to make a real difference to how ageing research progresses and how people view ageing.

We need fifty people to make a real change in funding policy so we can work towards healthy longevity.

https://www.facebook.com/…/draft-zero-gsap-ageing-and-healt… (please make sure to complete the 6 first lines at least before sending to the email indicated there).


WHO GSAP draft, healthy longevity and biomedical aging research.

Read more