Dr. Kristin Kostick discusses the intersection of faith and science, and how there may be room for both in a transhuman future.
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Category: life extension – Page 569
Increasing autophagy in macrophages is a promising avenue of research aiming at heart disease and other age-related diseaeses.
Today we thought it was a good time to take a look at a new study that demonstrates that increasing autophagy is a good approach to slowing aging and could be the foundation for a variety of therapies to treat age-related diseases.
What is Autophagy?
Autophagy is an intracellular degradation system that delivers unwanted cell components to a type of cellular garbage disposal system, known as the lysosome. The lysosome uses powerful enzymes that break down the unwanted material for recycling. However, as we age the lysosomes become clogged up with materials that are so fused together not even the potent enzymes can destroy them and this causes the lysosomes to become dysfunctional and eventually the cell dies. This is a particular problem for long lived cells with a very low rate of replacement such as the heart, the back of the eye, nerve cells and other cells that rarely divide if at all. Ultimately as more and more cells become dysfunctional over time due to lysosome dysfunction, tissue function become impaired and age-related disease sets in.
Due technical issues the Longevity Panel with Aubrey de Grey, Alexandra Stolzing and Oliver Medvedik + guests will be airing on Friday 9th June at 13:00 on the MMTP Facebook page. Apologies for the delay.
We are teaming up with LEAF/Lifespan.io for our Longevity Panel with Dr. Alexandra Stolzing, Dr. Aubrey de Grey, Dr. Oliver Medvedik and a number of other guests. We will be streaming the panel live to this page and we invite you to join us. It will also be made available later to view on Youtube.
This was originally scheduled for the 6th June but had to be rescheduled due to technical problems. We apologize for the inconvenience.
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Living forever would be boring
Posted in life extension
A brief article I wrote to rebut the misconception that longer—perhaps indefinite—lifespans would cause eternal boredom.
Alright. So, some people object you don’t want a very long lifespan because it would end up being boring. Even if a currently normal lifespan wasn’t enough, they argue, something like two hundred years would be more than enough to do anything worth doing. I wouldn’t bet my last cent on it.
Meet John and Jack, both born in the year 1400. John says he regrets he will not live past 1500 1490 1470 (that’s more like it). There are so many things he’ll miss out on centuries from now, he says.
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Japanese researchers have identified specific features of a gene that could hold the key to living beyond 100 and lead to the development of medicine for extra longevity.
Scientists at the Tokyo Metropolitan Institute of Gerontology, Keio University and other institutes said that centenarians and those close to that age share specific features of a gene that helps stem the spread of cancer and form bones.
“The gene we identified recently is not the sole actor determining longevity,” said Masashi Tanaka, chief of the Department of Clinical Laboratory at the institute. “But we believe that it plays a role in anti-aging in one way or another.”
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Only one more day to go before the live longevity panel with Dr. Aubrey de Grey, Dr. Alexandra Stolzing and Dr. Oliver Medvedik plus guests!
June 6th at 13:00 EST/18:00 UK we are teaming up with LEAF/Lifespan.io for a special Longevity Panel featuring Dr. Alexandra Stolzing, Dr. Aubrey de Grey, Dr. Oliver Medvedik and guests.
We will be streaming the panel live to this page and we invite you to join us. It will also be made available later to view on Youtube.
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LEAF attended the first Longevity and Cryopreservation Summit in Madrid recently. Here is another report from Elena Milova from the conference.
Elena Milova brings us another interesting interview from the recent International Longevity and Cryopreservation Summit where she caught up with Senior Scientist at the National Scientific and Technical Research Council (CONICET) of Argentina Dr. Rodolfo Gustavo Goya.
Dr. Goya admits he used to be a rebel from a young age. At 17 he decided he was not happy about aging and that he wanted to make a difference. He became a biochemist in the hope he could do something about age-related health deterioration and he continues to rebel against mother nature to this day. Dr. Goya has lead a number of studies on cellular reprogramming and restoration of function in important organs like the thymus and brain. He is also daring to challenge death itself by studying different aspects of cryopreservation and openly supports cryonics as a logical extension of medicine.
Please enjoy this interview with Dr. Aubrey de Grey, Chief Science Officer and Co-founder of SENS Research Foundation — one of the most successful advocacy and fundraising initiatives supporting breakthrough research on the main mechanisms of aging and age-related diseases. http://www.sens.org
In this video Dr. de Grey speaks about the progress in developing interventions to tackle age-related damages identified by SENS as the main ones.
Interviewer — LEAF/Lifespan.io Board member Elena Milova.
Dr. de Grey received his BA in Computer Science and Ph.D. in Biology from the University of Cambridge in 1985 and 2000, respectively. He is Editor-in-Chief of Rejuvenation Research (http://www.liebertpub.com/overview/rejuvenation-research/127/), is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the editorial and scientific advisory boards of numerous journals and organizations.
UK billionaire investor believes rejuvenation biotechnology will be the next mega-industry.
Many of you may already know about billionaire entrepreneur Jim Mellon and his interest in rejuvenation biotechnology. But for those of you who do not, we would like to introduce you to him and his exciting work.
About Jim Mellon