Lifeboat Foundation

During the ‘in vivo’ reprogramming process, cellular telomeres are extended due to an increase in endogenous telomerase. This is the main conclusion of a paper published in Stem Cell Reports by a team from the Spanish National Cancer Research Centre (CNIO). Their observations show, for the first time, that the reprogramming of living tissue results in telomerase activation and telomere elongation; thus reversing one of the hallmarks of aging: ‘the presence of short telomeres’.

“We have found that when you induce cell dedifferentiation in an adult organism, the telomeres become longer, which is consistent with cellular rejuvenation”, explains María A. Blasco, head of the CNIO Telomeres and Telomerase Group and leader of this research. This lengthening of the telomeres is an unequivocal sign of cell rejuvenation, which has been quantified for the first time here in a living organism.

Blasco and her colleagues have worked with the so-called “reprogrammable mice” –created by Manuel Serrano, also a CNIO researcher, whose group is also involved in this project. Broadly speaking, the cells of these transgenic animals carry the four Yamanaka factors (OSKM) whose expression is turned on when an antibiotic is administered. In doing so, the cells regress to an embryonic-like state, a condition known as known as pluripotency.

Continue reading “‘In vivo’ reprogramming induces signs of telomere rejuvenation” »

I have been slowly trying to evolve everyone’s thinking and knosledge about what Quantum is and its significant impact it is bringing to all industries as it relates to technology and health/ bio sciences.

My interest in Quantum Biology began when I was 12 years old although Quantum Bio then wasn’t even considered a reality. I had to at my age out of necessity as in my own father’s family had a Neuro and electrode defect impacting their hearts and muscle movements. So, being by nature, a person who dives deep into an interest I study thoroughly the neuro sensory pathways, the heart, the entire sensory pathways where the body continuously sends electro charges.

After many decades of my own research and studying on the side, I knew how much the impact quantum brings to the biological environment.

Continue reading “Can Space Travel Reverse Ageing? The Curious Case Of Astronaut Scott Kelly” »

It looks like Alzheimer’s is not a one way process!

New research study suggests early stage Alzheimer’s could be reversed using a repair approach to this age-related disease.

Check out our campaign today: https://www.lifespan.io/campaigns/cellage-targeting-senescen…c-biology/

https://curiosity.im/Skinter

You can help us find ways to remove them and stay healthy!

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Can science really enable us stick around on Earth forever? Experts haven’t developed ways to make us invincible, immortal beings who are unsusceptible to physical trauma or starvation. However, studies have been going on to make aging just another preventable disease. Effectively stalling the deterioration of our bodies would then mean humans could live indefinitely.

Peter Diamandis, co-founder of San Diego-based genotype research facility Human Longevity, Inc., spoke at the Singularity University in California last September about challenging aging and the deterioration of the body. The key to unlocking an indefinite lifespan was to improve the repair mechanisms of the body, said Diamandis. His research teams consider the possibility of using stem cells or nanomachines to regenerate our bodies.

Last year, researchers from the Stanford University School of Medicine have used chromosome extensions that dramatically increased the rate of cell division, a growth mechanism of our bodies that weakens over time. The development hints at a chance to turn back the biological clock.

Continue reading “Living Forever: What it Means to Have an ‘Indefinite Lifespan’” »

Oh, the logic of objections against rejuvenation! bigsmile

If you’ve ever tried to advocate for rejuvenation, you know it is hard. Usually, people deem the idea as crazy/impossible/dangerous well before you get to finish your first sentence. Living too long would be boring, it would cause overpopulation, ‘immortal’ dictators, and what you have. However, you’ve probably never heard anyone use the same arguments to say that we should not cure individual age-related diseases. This is largely because people have little to no idea about what ageing really is, and how it cannot be untangled from the so-called age-related pathologies. These are nothing more, nothing less, than the result of the life-long accumulation of several types of damage caused by the body’s normal operations. Unlike infectious diseases, the diseases of old age are not the result of a pathogen attack, but essentially of your own body falling apart. As I was saying, people are largely unaware of this fact, and therefore expect that the diseases of ageing could be cured one by one without having to interfere with the ageing process itself, as if the two weren’t related at all. The result of this false expectation would be that you could cure Alzheimer’s, Parkinson’s, etc., but somehow old people would still drop dead around the age of 80 just because they’re old. That’s like saying they died of being healthy.

Back to reality, this can’t be done. To cure the diseases of old age, you need to cure ageing itself. If, for whatever reason, you think that curing ageing as a whole would be a bad idea and it should not be done, the only option is to not cure at least some of the root causes of ageing. Consequently, some age-related pathologies would remain as untreatable as they are today.

Now, the typical objections raised against rejuvenation tend to sound reasonable at first. To some, the statement ‘We should not cure ageing because it would lead to overpopulation’ sounds self-evident. However, if we consider the implications of this statement, things start getting crazy. As said, not curing ageing implies not curing some of its root causes, which in turn implies not curing some age-related diseases. Therefore, the sentence ‘We should not cure ageing’ implies ‘We should not cure [insert age-related disease here] ‘. What happens when we reformulate typical objections to rejuvenation in this fashion?

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