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Category: life extension – Page 453

Announces the publication of a new 315-page open-access report: “National Longevity Development Plans: Global Overview 2019 (First Edition)”.

It offers comprehensive profiles of relevant initiatives in the UK, the Netherlands, Singapore, South Korea, Israel, Switzerland, Hong Kong, Japan, the USA, Spain, the European Union and China, and utilizes sophisticated analytical metrics to compare the overall strength, focus, proactivity and relevance of their Longevity-related projects, initiatives and development plans.

Link to the Report: https://www.aginganalytics.com/longevity-development-plans

#aging #ageing #longevity #ageingpopulation #demographicageing #aginganalytics #geroscience #governmentlongevity #industrialstrategy

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The latest SpaceX Dragon cargo mission to the International Space Station (ISS) included an experiment that could help to combat the ravages of time here on Earth. The European experiment will test how ceramic nanoparticles interact with cells to act as an anti-aging supplement that not only holds promise for alleviating the effects of growing old, but also for combatting chronic illness and space-related stresses for astronauts on prolonged space missions.

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AM I Wrong for wondering about Metformin and its true benefits against the Senesonic-Sensonic pandemic Plague mankind has called aging??? Metformin has been in use truly since the 1920’s and we have not found today an elderly person who is living 125 or 150 years who states they merely took metformin for diabetes??? Now Met has proven itself as a resistant against diabetes due to preventing the liver from making to much glucose that then enters the body. But is it a Longevity drug for mankind is the burning question??? You be the Judge… {I found this link on Antonei Benjamin Csoka group page on the book of faces} Respect r.p.berry & AEWR wherein we have found the causes and a cure for the Pandemic plague mankind has called aging… https://we search for partners and investors to join us in agings end…

Does it make sense to treat ageing as a disease?


Stem cell transplants have been of great interest to aging researchers, and, in a new study, they have successfully increased mouse lifespan by using stem cell therapy. While this has been previously achieved, this experiment was more refined than older studies and sheds new light on the potential of tissue regeneration through stem cells.

The significant extension of maximum lifespan could be considered an indication that any intervention is targeting a core hallmark of aging or, in the case of small increases of lifespan, at least indirectly influencing it.

Through bone marrow transplants, the researchers have significantly increased the lifespans of mice and believe that they are directly targeting an aging process directly [1]. Given that stem cell exhaustion is a hallmark of aging, they are likely correct.

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As he sits stroking his Rip Van Winkle-worthy beard, it’s easy to see how de Grey’s achieved this “kind of a spiritual leader-status,” as he calls it. He dives easily into intricate explanations of two research projects unfolding in the lab down the hall, eagerly describing how one studies mitochondrial mutations, which are thought to cause an increase in oxidative stress. The other looks at atherosclerosis, the narrowing and hardening of artery walls. If we understood more about this buildup, the logic goes, we could better clean it up before too much damage is done.

Though he attends lab meetings and oversees the SENS’s research, his primary task is convincing the general public that death is, in fact, bad and that we should be doing everything we can to stop it. This focus on messaging suits him just fine. “I’m not in this to do science for the sake of doing science,” he says. “I’m in it for the ultimate goal.” He does a “ridiculous” amount of media, he says, and gives around 50 talks a year, from Vietnam to the Czech Republic.

Back in April, at a San Francisco blockchain conference called Block 2 the Future, de Grey began his talk with a disclaimer: “I probably ought to start by emphasizing that I don’t know fuck-all about cryptocurrencies. I am really only here because I have apparently quite a significant fan base in this community, and I am delighted that I do.”

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Given the chance, there are very few of us who wouldn’t want to slow down the aging process. Chasing that fountain of youth is a major branch of medical science at the moment, and a hardy little worm known as C. elegans is probably the most prolific test subject. Now, a team at Scripps Research has found that blocking a particular enzyme can extend the lifespan of these worms by almost half again.

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Today, we want to spotlight a new publication that charts the senescence-associated secretory phenotype (SASP), which consists of the various secreted signals given out by senescent cells during aging.

Senescent cells and the SASP

As we get older, an increasing number of our cells enter into a state known as senescence. They cease dividing and supporting the tissues and organs of which they are part and, instead, secrete a range of harmful chemical signals. This cocktail of harmful signals is known as the senescence-associated secretory phenotype (SASP).

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