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Category: life extension – Page 383

This New AI-Driven Quiz Predicts Your Psychological Age

A questionnaire developed by XPRIZE and Deep Longevity claims to be able to accurately predict your psychological age by using artificial intelligence (AI) to analyze your answers, which theoretically should fall close to your chronological age. The questionnaire is developed from a study published in Aging that used AI in an attempt to identify key hallmarks of psychological aging and the top risk factors that affect mortality.

While the questionnaire seems like a fun insight into whether you’re an old soul or a young gun at heart, there is an important scientific basis for an age-predicting AI. The newly developed technology represents the first AI aimed solely at using psychological aspects to predict age. The researchers hope it can contribute to understanding the role psychological clocks play in overall aging, as well as improving mental health and the feeling of youth.

“For the first time, AI can predict human psychological and subjective age and help identify the possible interventions that can be applied in order to help people feel and behave younger,” said Alex Zhavoronkov, PhD, founder and CLO of Deep Longevity and co-author of the study, in a statement.

Genetically engineered T cells could lead to therapies for autoimmune diseases

A new study has found that a novel T cell genetically engineered by University of Arizona Health Sciences researchers is able to target and attack pathogenic T cells that cause Type 1 diabetes, which could lead to new immunotherapy treatments.

The immune system fights bacteria, viruses and other pathogens by utilizing several types of T , all of which have receptors that are specific to particular antigens. On killer T cells, the receptor works in concert with three signaling modules and a coreceptor to destroy the . Michael Kuhns, Ph.D., an associate professor in the UArizona College of Medicine—Tucson Department of Immunobiology, copied the evolutionary design to engineer a five-module , or 5MCAR, T cell.

“The 5MCAR was an attempt to figure out if we could build something by biomimicry, using some of evolution’s natural pieces, and redirect T cells to do what we want them to do. We engineered a 5MCAR that would direct killer T cells to target autoimmune T cells that mediate Type 1 diabetes,” said Dr. Kuhns, who is member of the UArizona Cancer Center, BIO5 Institute and Arizona Center on Aging. “So now, a killer T cell will actually recognize another T cell. We flipped T cell-mediated immunity on its head.”

Panelists at the Healthy Masters 2020 on What Can We Do to Improve Health and Longevity

Here the video of the first discussion panel out of two, during the celebration of the Healthy Masters Conference 2020, which took place on November 29, 2020. Nuno Martins, organizer and moderator of the event, asked all panelists to comment on the following theme: What can we do to improve our health and longevity. Given the essence of the event, the question was surrounded by the objective of achieving radical life extension or super longevity. My intervention starts at minute 20:13 and in the description of the video there are all the time marks that direct to the begining of each talk.

First discussion panel out of two, during the celebration of the Healthy Masters Conference 2020 which took place on November 29, 2020.
Nuno Martins, PhD, organizer and moderator of the event, asked all panelists to comment on the following theme: What can we do to improve our health and longevity?
Given the essence of the event, the question was surrounded by the objective of achieving radical life extension or super longevity.

Panelists in order of appereance:
* Naveen Jain: Founder and CEO of Moon Express Viome (00:21)
* Nichola Conlon, PhD: CEO & Founder of Nuchido (03:28)
* Kelsey Moody, PhD: Process Oriented Drug Developer and Executive (05:18)
* Peter Fedichev, PhD: Head of the Laboratory of Biological Systems (08:38)
* James Hughes, PhD: Executive Director of the Institute for Ethics and Emerging Technologies (12:12)
* María Entraigues Abramson: Global Outreach Coordinator for the SENS Research Foundation (15:14)
* Yael Sorek-Benvesti, PhD: CEO of Mediterranean Towers Venture (18:24)
* Andrés Grases, MBA: Owner and Editor of Transhumanplus.com (20:13)
* Ines O´Donovan: Founder of the Jeunessima Lifestyle Company (23:52)
* Reason, CEO of Repair Biotecnologies (27:39)
* Odette Tonnae: Founder of YOAKE, the Healthy Lifestyle Expertise.
Simulation at MIPT (31:53)

The Benefits Of Cardiovascular Fitness — Live Long Enough To Live Forever

It is the weekend and time for a new video… following on from last week, this time I am looking at the types of cardiovascular training and how they effect your body at the cellular level, so you can craft your own training program, suited to your lifestyle and preferences, that helps you slow the aging process so you can live long enough to live forever…and be fit enough to enjoy it to the maximum.

After all, if life is boring, why live forever?

In The Benefits Of Cardiovascular Fitness, I look at the benefits of training and exercise, both High Intensity Interval Training (HIIT) and Steady State Cardio training, and how they effect the body in different ways, making them both essential weapons in your arsenal against the effects of aging.

If you missed Why We Should Exercise Regularly — Ten Amazing Benefits, you can find that here… https://youtu.be/ZMXFBgcuaaI So go and get sweaty, and share your preferred workout regime with us in the comments below.

So go and get sweaty, and share your preferred workout regime with us in the comments below.

Continue reading “The Benefits Of Cardiovascular Fitness — Live Long Enough To Live Forever” | >

Researchers discover drug that reverses mental decline, aging

WASHINGTON (SBG) — Researchers studying cognitive deficits following traumatic brain injuries have discovered what they say is a revolutionary drug that could provide the cure for aging. The study by the University of California San Francisco has shown promising results among mice, essentially reversing age-related declines in memory. “We went on with this crazy experiment… and were able to return their cognitive function to as if they were never injured,” said Dr.

Using Stress To Your Advantage

Have you ever wondered why our bodies react as they do to stresses?

In this quick guide, I go right back to the primordial soup so to speak, and trace the factors that led to where we are today, and I finish off by looking at good and bad stresses so you can understand them, and use them to your advantage to stay fit and healthy, and even, maybe, to help you slow down aging…whilst we wait for the medical breakthroughs that will allow us to role back the years…

In Cellular Response To Stress — Using Stress To Your Advantage so you live healthier and longer.

We all want to live forever, well, I assume you do if you are following this channel anyway.
But how…

In How We Evolved With Stress — When Can Stress Be A Good Thing? I will look at how to live a healthier, happier and longer lifestyle to allow a healthier and happier life.

Continue reading “Using Stress To Your Advantage” | >

Aging, diet-induced obesity, and metabolic disease link explored in new research

Might want to dig deeper.

Unraveling the links among obesity, aging, telomere lengths and metabolic diseases is the subject of the study published today in Nature Metabolism by a collaborative research team at The University of Texas Health Science Center at Houston (UTHealth).

Telomeres act as protective caps at the end of chromosomes to prevent them from replication errors during cell divisions. Every time a chromosome replicates itself, telomeres shorten. When the telomeres become too short, the cell can no longer replicate its chromosomes safely and becomes arrested, or senescent. That shortening has been linked to the and development of degenerative diseases.

“Recent studies have also shown the connection between obesity-induced , such as Type 2 diabetes, and the accumulation of senescent cells, which entered the state of irreversible proliferation arrest,” said lead author Mikhail Kolonin, Ph.D., professor and Harry E. Bovay, Jr. Distinguished University Chair in Metabolic Disease Research with McGovern Medical School at UTHealth. “Cell senescence can be caused by telomere shortening due to excessive stem .”

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