Vice President for Research Technology and Innovation and Chair of the Department of Cell Stress Biology Roswell Park Comprehensive Cancer Center (Buffalo, NY) on systemic DNA damage and anti-aging therapies.
http://undoing-aging.org/videos/andrei-gudkov-presenting-at-…5y-bZmN_uU
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It might sound crazy to the masses, but life extension is a real thing. The science, also known as anti-aging medicine, indefinite life extension, experimental gerontology, and biomedical gerontology, is the study of slowing down or reversing the processes that create aging. The result? Maximum and average lifespan extended. The question is, do we need tech? Or should we begin to look at why our life spans aren’t already longer?
If you try to envision it, you might find yourself lost in a futuristic sci-fi film you’ve already seen. But it’s more than a concept fit for the silver screen. Life extension is a very real science, and is currently being worked on as you read this.
In genetics and developmental biology, somatic cell nuclear transfer (SCNT) is a laboratory technique for creating an ovum with a donor nucleus. It can be used in embryonic stem cell research, or in regenerative medicine where it is sometimes referred to as “therapeutic cloning”.
https://www.biointeractive.org/classroom-resources/somatic-c…94yzh8K2uw
Researchers at the University of Helsinki have shown why the regenerative capacity of the cells lining the intestines declines with age and that targeting a particular enzyme can restore the regenerative potential of this tissue.
Notum blocks the Wnt pathway
During normal function, the cells of the intestinal epithelium, a single cell layer that forms the lining of both the small and large intestine, are replaced by stem cells, which create healthy replacement cells to counter losses from injury, damage, disease, and aging. These cells are roused into action via the Wnt signaling pathway, which is activated through signals sent by other cells in the tissue.
Top-30 Longevity Conferences 2019–2020 is a 60-page open-access analytical report by Aging Analytics Agency that uses cost-benefit analysis to identify the Top-30 Longevity Conferences globally taking place in 2019–2020, including detailed analysis and infographics on their regional distribution, cost, and focus.
Link to the Report: https://www.aginganalytics.com/longevity-conferences
The report is complemented by a comprehensive online Longevity Conferences IT-Platform that contains data on 150 Longevity-related conferences taking place in 2019–2020.
Leading telomere researcher Maria Blasco press conference at the Ending Age-Related Diseases conference, New York, NY, July 12, 2019.
Our Ending Age-Related Diseases conference in New York is over for this year and has been a huge success. We had the opportunity to interview one of the speakers, Dr. Mar í a Blasco, during the conference, and we asked her more about her work with telomeres, telomerase therapy, and aging.
Telomere loss is a proposed reason we age
Telomere attrition—the wearing out of your chromosomes’ protective caps with age—is widely thought to be one of the major drivers of aging. With each division, telomeres shorten a little bit, and after 50–70 divisions, they become critically short. Once this threshold (the Hayflick limit) is hit, cells undergo replicative senescence, and their division comes to a grinding halt.
Researchers have uncovered more evidence that the key to longevity resides in a gene, SIRT6.
