Circa 2021 đ
CRISPR-induced KAT7 gene inactivation rejuvenates prematurely aging human cells and mice and promotes longevity.
Category: life extension – Page 359
If You Could, Would You Live Forever? David Sinclair on Extending Lifespan
This starts with Tysonâs deathism quote, but Iâm still a fan. I do wonder if heâll take a treatment when he sees everyone else rejuvenating around him.
Bionic eyes: How tech is replacing lost vision
This technology has to translate images into something the human brain can understand. Click the numbers in the interactive image below to find read about how this works.
There are a whole range of conditions, some which are picked up due to the aging process and others which may be inherited, that can cause sight deterioration.
Bionic eyes work by âfilling in the blanksâ between what the retina perceives and how it is processed in the brainâs visual cortex, that breakdown occurs in conditions which impact the retina. It is largely these conditions which bionic eyes could help treat.
Scientists âElatedâ
An international team of researchers claim to have slowed the signs of aging in mice by resetting their cells to younger states, using a genetic treatment.
To the scientists, The Guardian reports, itâs a breakthrough in cell regeneration and therapeutic medicine that doesnât seem to cause any unexpected issues in mice.
âWe are elated that we can use this approach across the life span to slow down aging in normal animals,â said Juan Carlos Izpisua Belmonte, Salk Institute professor and co-corresponding author of a new study published in the journal Nature Aging, in a statement. âThe technique is both safe and effective in mice.â
Dr. Kara Spiller, PhD â Immunomodulatory Biomaterials In Regenerative Medicine â Drexel University
Immunomodulatory Biomaterials In Regenerative Medicine â Dr. Kara Spiller-Geisler, Ph.D., Drexel University School of Biomedical Engineering, Science and Health Systems.
Dr. Kara Spiller, PhD (https://drexel.edu/biomed/faculty/core/SpillerKara/) is Associate Professor in the Biomaterials and Regenerative Medicine Laboratory at Drexel University, in Philadelphia.
Dr. Spiller received her bachelorâs, masterâs, and doctoral degrees in biomedical engineering from Drexel University where she conducted her doctoral research in the design of semi-degradable hydrogels for the repair of articular cartilage in the Biomaterials and Drug Delivery Laboratory at Drexel, and in the Shanghai Key Tissue Engineering Laboratory of Shanghai Jiao Tong University.
After completing her PhD, when she received the award for Most Outstanding Doctoral Graduate: Most Promise to Enhance Drexelâs Reputation, she conducted research in the design of scaffolds for bone tissue engineering as a Fulbright Fellow, in the Biomaterials, Biodegradables, and Biomimetics (the 3Bs) Research Group at the University of Minho in Guimaraes, Portugal. She also worked as a Postdoctoral Scientist at Columbia University.
Dr. Spiller is currently conducting research in the design of immuno-modulatory biomaterials, particularly for bone tissue engineering. Her research interests include cell-biomaterial interactions, biomaterial design, and international engineering education.
CRISPR On-Off Switch Will Help Unlock the Secrets of Our Immune System
Can we turn upâor dial downâtheir fervor by tweaking their genes?
Enter a new kind of CRISPR. Known mostly as a multi-tool to cut, snip, edit, or otherwise kneecap an existing gene, this versionâdubbed CRISPRaâforcibly turns genes on. Optimized by scientists at Gladstone Institutes and UC San Francisco, the tool is counterbalanced by CRISPRiââiâ for âinterference,â which, you guessed it, interferes with the geneâs expression.
Though previously used in immortal cells grown in labs, this is the first time these CRISPR tools are rejiggered for cells extracted from our bodies. Together, the tools simultaneously screened nearly 20,000 genes in T cells isolated from humans, building a massive genetic translatorâfrom genes to functionâthat maps how individual genes influence T cells.
