Circa 2017 face_with_colon_three
For the first time, scientists have found a genetic mutation that appears to offer a measure of protection against some of the biological effects of ageing.
And, as far as we know, it looks like the only community in the world known to harbour it is an Old Order Amish community living in Indiana.
Sirtuins, telomeres, A.I. experiment with vitamin A and personalized medicine, a bit of everything here.
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Space is getting crowded. Aging satellites and space debris crowd low-Earth orbit, and launching new satellites adds to the collision risk. The most effective way to solve the space junk problem, according to a new study, is not to capture debris or deorbit old satellites: it’s an international agreement to charge operators “orbital-use fees” for every satellite put into orbit.
Dr. Michael R. Rose is Professor at Department of Ecology and Evolutionary Biology at University Of California, Irvine. His main area of work has been the evolution of aging.
“Our task is to make nature, the blind force of nature, into an instrument of universal resuscitation and to become a union of immortal beings.“
- Nikolai F. Fedorov
We hold faith in the technologies & discoveries of humanity to END AGING and Defeat involuntary Death within our lifetime.
Working to Save Lives with Age Reversal Education.
========== Perpetual Life Creed ==========
DNA damage is common to our cells, but when we’re young our bodies can fix it pretty easily. Unfortunately we lose that ability over time, leading to many of the symptoms of aging that we know all too well. A new study from MIT has found that reactivating a certain enzyme improves repair of DNA damage in neurons, which helps Alzheimer’s patients and others with cognitive decline.
Previous studies by the team have shown that an enzyme called HDAC1 seems to be involved in DNA repair in neurons. For the new study, the researchers examined what happens when HDAC1 doesn’t do its job.
The team engineered mice to be deficient in HDAC1, and monitored their health compared to normal mice. Things looked good during the animals’ youth – there were no differences in DNA damage or behavior between the two groups. But as they aged, the decline became clear.
If you’re interested in superlongevity and superintelligence, then I have a book to recommend., by Sonia Contera, is a book about the intersection of biotech and nanotech. Interesting and well written for the layman, the book covers some of the latest developments in nanotechnology as it applies to biological matters. Although there are many topics, I was primarily interested in the DNA nanobots, DNA origami, and the protein nanotechnology sections. My interest is piqued in these arenas due to my expectation that DNA nanobots and protein nanobots, as well as complex self-assembled custom nanostructures, are going to be key to some of the longevity technologies and some of the possible substrates for mind uploading that are key to superlongevity and superintelligence. There are also sections in the book on 3D bioprinted organs — progress and possibilities, as well as difficulties.
There is even a section that clearly was written specifically to address a discussion that has engaged my friends, Dinorah Delfin and Dan Faggella. The title is:
FUTURE DEVICES: QUANTUM PHYSICS MEETS BIOLOGY MEETS NANOTECHNOLOGY
Now, some might be tempted to consider that particular combination to be “woo woo”, however, please keep in mind the author’s credentials. Sonia Contera is a professor of biological physics in the Department of Physics at the University of Oxford.
Increasingly, scientists are gaining control over matter at the nanometer scale. Spearheaded by physical scientists operating at the interfaces of physics and biology, advances in nanoscience and technology are transforming how people think about life and treat human health.
If you’re interested in superlongevity and cognitive enhancement, I have a YouTube video to recommend. Our good friend, Ira Pastor, on his excellent podcast ideaXme, discusses with Dr. Rudolph Tanzi the topic of inflammaging, specifically brain inflammation, plaque, tau tangles, brain health, and Alzheimer’s disease. Then they discuss some emergent therapies to prevent Alzheimer’s by protecting the neurons.
The discussion is concise and complete, but also very easy to follow.
Ira Pastor, ideaXme life sciences ambassador, interviews Dr. Rudolph Tanzi, Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard University, Vice-Chair of Neurology, Director of the Genetics and Aging Research Unit, and Co-Director of the Henry and Allison McCance Center for Brain Health at Massachusetts General Hospital.
You might be interested in my latest interview with Natasha Vita-More, transhumanist writer and executive director of Humanity+, covering human augmentation, the world transhumanist movement and whole-body prosthetics.
Trying to grow my transhumanism related channel so super grateful for any subs: https://www.youtube.com/channel/UCnVLqMgLDwO-aSk5YcYo1dA…
I interview Natasha Vita-More, a transhumanist thinker who wrote the ‘Transhumanist Statement’ and is the Executive Director of Humanity+, formerly the World Transhumanist Association.
Biological age and biomarkers improved to that of rats half their age. Blog post from the Live Forever Club.
