Lifeboat Foundation

A recent study has taken an in-depth look at the age-related changes that occur in the microbiome, particularly in regards to bacterial populations.

A detailed look at bacterial populations in the gut microbiome

The publication contains multiple graphs that track age-related changes to various bacterial populations in the gut. These graphs show a common trend: the abundance of these bacterial species increases with aging but then falls significantly in extreme old age. On these charts, Groups 1–5 contain various ages of children, Group 6 consists of 19- to 29-year-olds, and each following group is ten years older than the previous, with Group 14 containing 99- to 110-year-olds.

Watch it 👇.

MOTHERBOARD met up with Russian billionaire Dmitry Itskov at his Global Future 2045 Conference in New York City to talk about immortality, spirituality, and the coming age of cybernetic avatar-based living.

Continue reading “Dmitry Itskov on the Philosophy of Immortality” »

In mouse studies, a “methylation clock” on the ELOVL2 gene ticks toward impaired vision, but when gene expression was boosted, age-related visual function improved.

A lengthy-named gene called Elongation of Very Long Chain Fatty Acids Protein 2 or ELOVL2 is an established biomarker of age. In a new paper, published online January 14, 2020 in the journal Aging Cell, researchers at University of California San Diego School of Medicine say the gene appears to play a key role in age-associated functional and anatomical aging in vivo in mouse retinas, a finding that has direct relevance to age-related eye diseases.

Specifically, the research team, led by senior author Dorota Skowronska-Krawczyk, PhD, assistant professor in the Viterbi Family Department of Ophthalmology at UC San Diego Shiley Eye Institute, found that an age-related decrease in ELOVL2 gene expression was associated with increased DNA methylation of its promoter. Methylation is a simple biochemical process in which groups of carbon and hydrogen atoms are transferred from one substance to another. In the case of DNA, methylation of regulatory regions negatively impacts expression of the gene.

Continue reading “Researchers Identify Gene with Functional Role in Aging of Eye” »

“A neuroscientist explains how our brains age and provides tips for aging with more vitality and happiness.”

https://greatergood.berkeley.edu/topic[/li

If you’d like to share this article please share it from the link here: https://www.facebook.com/383136302314720/posts/516809088947440/

Continue reading “What Neuroscience Can Teach Us About Aging Better” »

https://www.youtube.com/watch?v=qMGAane9QVc

AgeX Therapeutics Inc (NYSEAMERICAN: AGE) CEO Michael West sat down with Proactive’s Christine Corrado at the Biotech Showcase 2020 in San Francisco. The Alameda, California biotechnology company is developing a cell therapy treatment for metabolic disorders such as Type 2 diabetes.

Jane McLelland beat cervical, lung, and blood cancers using the missing link to defeat cancer: starving it. She is partnering with Life Extension® to help other patients achieve the same results.

By Laurie Mathena.

After getting a considerable success in convincing scientists and investors, in the last decades, that undoing aging through a damage repair approach is possible and desirable, Aubrey de Grey is turning his advocacy efforts to politicians. In this video, he explains why.

https://thelongevityforum.com/
Aubrey de Grey delivers a keynote on the next steps for longevity for policy makers.

Continue reading “Aubrey de Grey, CSO, SENS, ‘Scientists, check — Investors, check — Next up, policy makers’” »

There are a few dozen antiaging rejuvenation treatments that are progressing through pre-clinical and clinical trials.

Lifespan.io is tracking the antiaging rejuvenation treatments on a rejuvenation roadmap.

Two treatments are in phase 3 clinical trial.