Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: life extension – Page 285

For centuries, scientists have tried to work on formulas to extend human life. While scientific and medical advancements have pushed the average human life expectancy to 71 years worldwide, researchers are still trying to find out if it can be extended further. Now, a group of scientists is leaning on artificial intelligence (AI) to combine conventional medicine to treat diseases and prevent them to extend longevity.

Conventional medicine has been the go-to tool for scientists to treat diseases and effectively extend life expectancy. But it has limitations too. While it can treat diseases, it’s not very effective in detecting early signs of an ailment that can reduce life expectancy. But combining AI, fundamental research and medicine could bring about a change in the research of extending human life. Dubbed as Longevity medicine, the scientists — Alex Zhavoronkov, Evelyne Yehudit Bischof and Kai-Fu Lee — proposed a framework. Their article was published in the journal Nature Aging.

Dr Zhavoronkov is a computer scientist with a doctorate in biophysics. Bischof is a practicing doctor who is researching on aging and gerooncology at the University Hospital Basel in Switzerland. Lee is known for his expertise in AI.

Scientists have proposed an artificial intelligence-based framework that can analyze millions of parameters and help fight aging.

Continue reading “Longevity Medicine: Scientists Develop Framework to Apply AI in Extending Lifespan” | >

This is the first part of the interview with Harold Katcher in Modern Healthspan YouTube channel.

Dr. Harold Katcher is a professor of Biology at the University of Maryland. He has been a pioneer in the field of cancer research, in the development of modern aspects of gene hunting and sequencing. He carries expertise in bioinformatics, chronobiology, and biotechnology. Dr. Katcher is currently working in the capacity of Chief Technical Officer at Nugenics Research exploring rejuvenation treatments in mammals.
In May 2020 there was a paper published on biorxiv about the rejuvenation of rats by over 50%. We did a review of the paper which you can find linked to above. In this interview series we talk with Dr. Harold Katcher, one of the main authors of the paper about the experiment, the steps to get validation, commercialization and how the results fit into his theories of aging.

In this video we talk about the actual experiment and some of the results that Dr. Katcher and his team saw.

Continue reading “Reversed Age by Over 54% Study” | >

‘The Death of Death’ — David Wood and Jose Cordeiro.

“La mort de la mort — les avancées scientifiques vers l’immortalité” was published on 21st January 2021 and is available in bookshops throughout France, Belgium, Luxembourg, and Switzerland, as well as online — see e.g. https://www.amazon.fr/mort-avanc%C3%A9es-scientifiques-vers-…875422200/

To mark the occasion of the publication, Sergey Young, Founder of the Longevity Vision Fund, asked a number of questions to the book’s co-authors, José Cordeiro and David Wood.

Continue reading “Introducing La Mort de la Mort — English” | >

Forever we have held a view that AGING, DISEASE & DEATH is an un-alterable eventuality, those who dared question were ostracised for playing God.

If you choose to look deeper you will surely be amazed. Bowhead whales live for over 200 yrs “Turriptosis Dohnri” is a Jellyfish that lives forever. Can these #genetics traits be replicated in humans? Could the removal of #senescence #cells that accelerates aging be the answer Is it even possible to control or reverse aging? Can we grow old healthily? 150000 die every day & over 100000 of them are caused by aging.

Catch Joao Pedro de Magalhaes microbiologist at Centaura & founder at Magellan Science Ltd. share his insights on the science of #humanlongevity #gerontology.

Change Transform INDIA-CHANGE I M POSSIBLE is a podcast & a platform for the brave Disruptors who don’t conform to the convention. subscribe, support & share India’s 1st #futuretech #podcast #agereversal #reverseaging #longevity #immortality #science

Continue reading “Slowing Ageing — Joao Pedro Magalhaes- Prof University of Liverpool & Founder Magellan Science Ltd” | >

Fair to say that we all assume that aging is inevitable. In reality however, there is no biological law that says we must age. Over the years we’ve seen a variety of theories proposed to explain why we age including the accumulation of damage to our DNA, the damaging effects of chemicals called “free radicals, changes in the function of our mitochondria, and so many others.

Our guest today, Dr. David Sinclair, believes that aging is related to a breakdown of information. Specifically, he describes how, with time, our epigenome accumulates changes that have powerful downstream effects on the way our DNA functions. Reducing these changes to the epigenome is achievable and in fact, even taking it further, his research now reveals that the epigenome can be reprogrammed back to a youthful state.

David A. Sinclair, PhD, AO is Professor of Genetics at Harvard Medical School, and is the author of Lifespan — Why We Age and Why We Don’t Have To. He is the Founding Director of the Paul F. Glenn Center for the Biological Mechanisms of Aging at Harvard. One of the leading innovators of his generation, he is listed by TIME magazine as one of the “100 most influential people in the world” (2014) and top 50 most important people in healthcare (2018). He is a board member of the American Federation for Aging Research, a Founding Editor of the journal Aging, and has received more than 35 awards for his research on resveratrol, NAD, and reprogramming to reverse aging, which have been widely hailed as major scientific breakthroughs and are topics we discuss in our time together.

In 2018, Dr. Sinclair became an Officer of the Order of Australia, the equivalent of a knighthood, for his work on national security matters and human longevity. Dr. Sinclair and his work have been featured on 60 Minutes, Today, The Wall Street Journal, The New York Times, Fortune, and Newsweek, among others.

Continue reading “The Empowering Neurologist — David Perlmutter M.D., and Dr. David Sinclair” | >

A team of scientists from the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW) inGermany, Givskud Zoo–Zootopia in Denmark and the University of Milan in Italy succeeded in producing the very first African lionin-vitroembryos after the vitrification of immature oocytes. For this specific method of cryopreservation, oocytes are collected directly after an animal is castrated or deceased and immediately frozen at-196°C in liquid nitrogen. This technique allows the storage of oocytes of valuable animals for an unlimited time, so that they can be used to produce offspring with the help of assisted reproduction techniques. The aim is to further improve and apply these methods to save highly endangered species such as the Asiatic lion from extinction. The current research on African lions as a model species is an important step in this direction. The results are reported in the scientific journal Cryobiology.

Lion oocytes are presumed to be very sensitive to chilling due to their high lipid content, resulting in poor revival following slow cooling. Vitrification can circumvent this problem, as the cells are frozen at ultra-fast speeds in solutions with a very high concentration of cryoprotective agents. This method prevents the formation of ice crystals in the cells, which could destroy them, and enables them to remain intact for an unlimited time to allow their use later on.

For the present research, the scientists collected oocytes from four African lionesses from Givskud Zoo—Zootopia after the animals had been euthanised for the purpose of population management. Half of the oocytes (60) were vitrified instantly. After six days of storage in liquid nitrogen, the vitrified oocytes were thawed and subjected toin-vitromaturation in an incubator at 39°C for a total of 32–34 hours. The other half (59) were used as control group and directly subjected toin-vitromaturation without a step of vitrification. Mature oocytes of both groups were then fertilized with frozen-thawed sperm from African lion males. “We could demonstrate a high proportion of surviving and matured oocytes in the group of vitrified oocytes. Almost 50% of them had matured, a proportion similar to that in the control group,” says Jennifer Zahmel, scientist at the Department of Reproduction Biology at the Leibniz-IZW.

Read more | >

It is true. From its effect on biomarkers such as heat shock proteins and Fox 03, through to real world impacts on cardiovascular health, to improving mood, helping you live longer healthier and reducing your chance of dying before your time. I think we all know saunas are really great for you, but this will give you all the scientific reasons why… Taking it easy and relaxing for half an hour… Is not just wasting your time… Changes today will make tomorrow better. #saunas

I am going to give you the best reasons in the world to sit back and take it easy in a nice warm environment, and to just forget the troubles of the world.
Maybe play some music, or a podcast, or listen to a book, or just meditate, just relax and take it easy.
It is for your own health after all!!

How about clicking here and watching the video I did on good and bad stress.

Continue reading “Sauna Exercise Mimetic — The Science Of The Amazing Health & Longevity Benefits” | >