YOU’RE INVITED! — OPEN TO CI MEMBERS, NON-MEMBERS AND THE GENERAL PUBLIC2023 Cryonics Institute Annual General MeetingSUNDAY — SEPT 10, 2023AGM Location: Infinity Hall & Sidebar 16,650 E 14 Mile RoadFraser, MI 48026phone: 586–879-6157website: infinityhallsidebar.com2023 AGM DetailsSunday, September 10, 2023Event start time: 3:00 pm Eastern TimeEvent end time: 6:30 pmFacility ToursTours of the Main and new […].
For C. Elegans, but but a cool use for the technology.
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Here Prof Kaeberlein talks about the million molecule challenge and why he thought that it was necessary.
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Dr. Kaeberlein’s research interests are focused on biological mechanisms of aging in order to facilitate translational interventions that promote healthspan and improve quality of life. He has published more than 200 scientific papers, has been recognized by several prestigious awards, and has Fellow status in the American Association for the Advancement of Science (AAAS), the American Aging Association, and the Gerontological Society of America (GSA). Dr. Kaeberlein is currently the CEO of the American Aging Association and has served on the Board of Directors for the Federation of American Societies for Experimental Biology (FASEB), AGE, and GSA. Dr. Kaeberlein is the founding Director of the UW Healthy Aging and Longevity Research Institute, the Director of the UW Nathan Shock Center of Excellence in the Basic Biology of Aging, Director of the Biological Mechanisms of Healthy Aging Training Program, and founder and co-Director of the Dog Aging Project.
Most of us who’ve reached middle age have noticed a slowing in memory and cognition, but scientists don’t have a clear picture of the molecular changes that take place in the brain to cause it.
Now, a study in mice has determined that the most pronounced changes occur in the white matter, a type of nervous system tissue that’s integral to transmitting signals across the brain. The study also examined two treatments — caloric restriction and infusions of plasma from young mice — that affect certain regions of the brain, with the plasma appearing to slow the age-related decline.
The results offer insight into the cognitive decline of normal aging, as well as the way aging contributes to neurodegenerative conditions such as Alzheimer’s and Parkinson’s diseases and multiple sclerosis.
Imagine walking on a treadmill and time is the speed at which the belt moves. As you age, the speed of the belt increases, representing time passing faster and faster as we age. However, what if we could speed up and run faster than the belt? This is widely known as the concept of Longevity Escape Velocity (LEV), which is essentially the idea of outrunning time itself.
Longevity Escape Velocity refers to a future scenario in which medical progress and innovation allows scientists to extend human lifespan at a rate greater than the passage of time. Imagine a world where each passing year not only adds another year to our lives but also enhances our health, vitality, and functional abilities. This concept, popularised by Biomedical gerontologist Dr. Aubrey de Grey, centres around the idea of developing rejuvenation therapies that repair age-related damage at the cellular and molecular levels, with the aim of effectively reversing the aging process.
Organisations such as Dr Aubrey de Grey’s LEV Foundation are playing a huge role in attempting to achieve this extraordinary milestone by striving to speed up the development of life extending therapies and endeavouring to make them accessible to all. It can be argued that they tend to focus on high risk, high reward research that other institutions might overlook due to its experimental nature, however without those that dare to think big, developments in longevity science will not make the strides needed to make a real impact in our future.
An injection of a specific blood factor can replicate exercise’s brain benefits, offering potential treatments for age-related cognitive decline.
Pre-clinical trials by University of Queensland scientists have found that an injection of a specific blood factor can replicate the benefits of exercise in the brain.
Dr. Odette Leiter and Dr. Tara Walker from UQ’s Queensland Brain Institute led a team that discovered platelets, the tiny blood cells critical for blood clotting, secrete a protein that rejuvenates neurons in aged mice in a similar way to physical exercise.
How would it feel to control objects with your mind? Or hear colors? Or maybe even live forever? Well, if you want to find out, all you have to do is become a cyborg. How would being part machine affect us? Would it cause a greater divide between the rich and the poor? And is this the next step in human evolution?
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Transhumanism — advocates strongly for humans to develop and make widely available sophisticated technologies that enhance human physiology and intellect greatly. In layman’s terms, transhumanists would like for human beings to become cyborgs; cybernetic organisms.
As such, transhumanist concepts feature greatly in science fiction. Cyborgs are commonly seen in all forms of science fiction media…
Concepts of transhumanism and the wish to improve human physiology beyond normal bounds comes from an age-old human desire. That desire is the desire for immortality. Such wishes have been expressed in literature and rhetoric as far back as the early Bronze Age.
It would still take quite some time after the industrial revolution for early transhumanist thinking to develop. Advanced technological growth could eventually allow humans to accomplish much more than a fully fit natural born and grown human can.
As of 2020, transhumanists are playing an established role in global politics in the west, with many of them even being elected to legislature within their respective states. For now, transhumanism just seems like a concept that may or may not be realized practically in the distant future, far beyond our lifetimes.
While being engrossed in our fantasies about the possibilities that may be brought about by cybernetic enhancements to the human body, we tend to forget the important minor details that are very easy to miss. In case of a parts malfunction leading to injury of other people, who is liable? The wearer or the manufacturer of the part?
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