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Archive for the ‘life extension’ category: Page 245

Sep 26, 2020

Humans live much longer than chimps due to a slower epigenetic ‘clock’

Posted by in categories: biotech/medical, chemistry, genetics, life extension

Lil bits of info on DNA methylation, clocks.


Breakthrough advances in medicine and better nutrition have dramatically improved the longevity of the average human over the past two centuries. But that’s not to say that some couldn’t go on to live a long life even before the advent of modern medicine. As long as they were spared by disease, wars, and other risks that can bring an untimely death, humans could live to see their 70s, 80s, and even reach 100 years old as far back as ancient Rome.

The longevity of humans is somewhat exceptional among primates. Chimpanzees, our closest living relatives, rarely make it past age 50, despite them sharing over 99% of our DNA. In a new study, researchers think they’ve found our secret: chemical changes along our genome that occurred around 7–8 million years ago when our ancestors branched away from the lineage of chimps.

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Sep 24, 2020

Diabetes Drug Metformin May Protect Aging Brains

Posted by in categories: biotech/medical, life extension, neuroscience

WEDNESDAY, Sept. 23, 2020 (HealthDay News) — A common type 2 diabetes drug called metformin may have an unexpected, but positive, side effect: New research suggests that people taking the drug appear to have significantly slower declines in thinking and memory as they age.

“Our six-year study of older Australians with type 2 diabetes has uncovered a link between metformin use and slower cognitive [mental] decline and lower dementia rates,” said study author Dr. Katherine Samaras. She’s the leader of the healthy aging research theme at the Garvan Institute of Medical Research in New South Wales, Australia.

“The findings provide new hope for a means of reducing the risk of dementia in individuals with type 2 diabetes, and potentially those without diabetes,” Samaras said.

Sep 23, 2020

Targeting the Mechanisms of Aging Across Species

Posted by in categories: biotech/medical, life extension, neuroscience, transhumanism

Targeting Mechanisms of Aging Across Species — I am joined on this episode of ideaXme by Dr. Matt Kaeberlein, Professor of Pathology, Adjunct Professor of Genome Sciences, and Adjunct Professor of Oral Health Sciences, University of Washington, to discuss his research focus on cross-species mechanisms of aging, in order to facilitate interventions that extend healthspan and improve quality of life — #Ideaxme #Health #Wellness #Longevity #Aging #LifeExtension #Rapamycin #MTor #CElegans #ExtracellularVesicles #Geroscience #GenomicInstability #AlzheimersDisease #Neurodegeneration #Parkinsons #MitochondrialDysfunction #OralHealth #SystemsBiology #DogAgingProject #Science #Transhumanism #Innovation #Immortality #IraPastor #Bioquark #Regenerage The Dog Aging Project.


Ira Pastor, idea me life sciences ambassador and founder of Bioquark, interviews Dr. Matt Kaeberlein, Professor of Pathology, Adjunct Professor of Genome Sciences, and Adjunct Professor of Oral Health Sciences at the University of Washington.

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Sep 23, 2020

Boxer George “Monk” Foreman III talks of Compassion and Everybody Fights!

Posted by in categories: business, life extension

Boxing, Business, and Well-Being — I am joined on this episode of ideaXme by George Foreman III; entrepreneur, professional boxer, trainer, coach, son / business partner of former two-time heavyweight boxing champion George Foreman, and founder of EverybodyFights, a rapidly expanding chain of high-end, state-of-the-art boxing and fitness gyms — #Ideaxme #Health #Wellness #Boxing #GeorgeForeman #Fitness #Gyms #Nutrition #Longevity #Aging #Healthspan #Lifespan #LifeExtension #Business #Entrepreneurship #Innovation #Startup #IraPastor #Bioquark #Regenerage


Ira Pastor, ideaXme life sciences ambassador, interviews George “Monk” Foreman III; entrepreneur, professional boxer, trainer, coach, and Founder of Everybody Fights.

Continue reading “Boxer George ‘Monk’ Foreman III talks of Compassion and Everybody Fights!” »

Sep 23, 2020

Is Aging a Disease You Can Reverse? A Look at the Science Behind the Longevity Movement

Posted by in categories: biotech/medical, life extension, science

We all want to know how to live longer, but is a prolonged life a healthy, happy one? One Vogue writer looks at the science that says it might be possible.

Sep 23, 2020

David Sinclair talks about human rejuvenation (Excerpt with S/T in Spanish)

Posted by in categories: biotech/medical, life extension

Short excerpt of a recent interview with Dr. David Sinclair published in the Youtube channel “Think Inc.”


Short excerpt of an interview with Dr. David Sinclair published in the Youtube channel “Think Inc.“
During the interview, Dr. Sinclair referres to the possibility of turning back the biological aging clock of the entire human body, through partial cellular reprograming in the not so distant future.

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Sep 20, 2020

Aubrey de Grey’s Prediction for 2020

Posted by in category: life extension

Aubrey de Grey, Chairman and Chief Science Officer of the Methuselah Foundation, presents a realistic scenario for 2020 in which everyone knows we will defeat the aging process.

Sep 15, 2020

Dr. Brian Kennedy — Preventive Medicine in an Aging Society

Posted by in categories: biotech/medical, life extension

At our first online conference, Ending Age-Related Diseases 2020, Dr. Brian Kennedy of the National University of Singapore discussed the aging population of Singapore, the need for comprehensive healthcare, alpha-ketoglutarate and its effects against frailty in mice, ongoing trials of ketoglutarate in humans, spermidine against obesity, the role of biomarkers, and the importance of keeping people well rather than simply treating them when they are sick.

Sep 15, 2020

Ageing Can Be A Thing Of The Past

Posted by in category: life extension

#aubreydegrey #ageing #ucaststudios #thetalkspot

The Talk Spot is an interview show where we have guests from all backgrounds on. This episode features returning guest Aubrey de Grey.

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Sep 14, 2020

New Map Charts Genetic Expression Across Tissue Types, Sexes

Posted by in categories: biotech/medical, genetics, life extension, neuroscience, sex

From the data, the GTEx team could identify the relationship between specific genes and a type of regulatory DNA called expression quantitative trait loci, or eQTL. At least one eQTL regulates almost every human gene, and each eQTL can regulate more than one gene, influencing expression, GTEx member and human geneticist Kristin Ardlie of the Broad Institute tells Science.

Another major takeaway from the analyses was that sex affected gene expression in almost all of the tissue types, from heart to lung to brain cells. “The vast majority of biology is shared by males and females,” yet the gene expression differences are vast and might explain differences in disease progression, GTEx study coauthor Barbara Stranger of Northwestern University’s Feinberg School of Medicine tells Science. “In the future, this knowledge may contribute to personalized medicine, where we consider biological sex as one of the relevant components of an individual’s characteristics,” she says in a statement issued by the Centre for Genome Regulation in Barcelona, where some of the researchers who participated in the GTEx project work.

Another of the studies bolsters the association between telomere length, ancestry, and aging. Telomere length is typically measured in blood cells; GTEx researchers examined it in 23 different tissue types and found blood is indeed a good proxy for overall length in other tissues. The team also showed that, as previously reported, shorter telomeres were associated with aging and longer ones were found in people of African ancestry. But not all earlier results held; the authors didn’t see a pattern of longer telomeres in females or constantly shorter telomeres across the tissues of smokers as previous studies had.

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