Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: life extension – Page 226

Join us on Patreon!
https://www.patreon.com/MichaelLustgartenPhD

Levine’s Biological age calculator is embedded as an Excel file in this link from my website:

Quantifying Biological Age

Papers referenced in the video:
Inter-and intra-individual variability in daily resting heart rate and its associations with age, sex, sleep, BMI, and time of year: Retrospective, longitudinal cohort study of 92,457 adults.
https://pubmed.ncbi.nlm.nih.gov/32023264/

Heart rate variability with photoplethysmography in 8 million individuals: a cross-sectional study.

Continue reading “Blood Test #2 in 2022: Supplements, Cardiovascular Fitness Metrics (HRV, RHR)” | >

Boston medical researchers in a new groundbreaking study have discovered a “vicious cycle” between daytime napping and Alzheimer’s dementia.

The Brigham and Women’s Hospital researchers found a link between the two: Excessive daytime napping predicted an increased future risk of Alzheimer’s dementia, and a diagnosis of Alzheimer’s dementia sped up the increase in daytime napping during aging.

Daytime napping is common among older adults, but researchers have not known the relationship between daytime napping and cognitive aging.

Read more | >

Technique allows researchers to toggle on individual genes that regulate cell growth, development, and function.

By combining CRISPR technology with a protein designed with artificial intelligence, it is possible to awaken individual dormant genes by disabling the chemical “off switches” that silence them. Researchers from the University of Washington School of Medicine in Seattle describe this finding in the journal Cell Reports.

The approach will allow researchers to understand the role individual genes play in normal cell growth and development, in aging, and in such diseases as cancer, said Shiri Levy, a postdoctoral fellow in UW Institute for Stem Cell and Regenerative Medicine (ISCRM) and the lead author of the paper.

Read more | >

Summary: Oleic acid produced in the brain is an essential regulator of processes that enable memory, learning, and mood regulation. Oleic acid, which is abundant in olive oil, also promoted neurogenesis and increases cell proliferation.

Source: Baylor College of Medicine.

Many people dread experiencing the cognitive and mood declines that often accompany reaching an advanced age, including memory disorders such as Alzheimer’s disease and mood conditions like depression.

Read more | >

This disparity gets at the difference between one’s chronological age — how old they are in years — and their biological age, which is how their body has aged naturally and in response to its environment. The two can diverge in ways that are either blessings or curses. Hence why those who grow up under extreme stress or in polluted environments may look much older than they actually are.

And yellow-bellied marmots can tell us something about these two ages.

Yellow-bellied marmots (Marmota flaviventer) are no burrow-dwelling meteorologists like the groundhog. They may sound craven, but these quirky critters, also known as whistle pigs, make for fascinating subjects: the cat-sized rodents have a longer lifespan than expected for a mammal of their size. On average, marmots live 15 years.

Read more | >

A little confusing. Cure aging in 20 years but you’re not a longevity company?

Altos Labs recently exited stealth mode to announce $3 billion in funding, reportedly from investors including Jeff Bezos, and a team full of Nobel Prize winners and pioneering scientists. However, the secretive company’s representatives insist that “Altos is not an anti-aging or longevity company”. Despite this, a key member of their scientific leadership recently publicly stated that he is convinced that, using the same technologies they are working with at Altos, we will be able to prevent aging within twenty years.

The scientist making these bold statements is Juan Carlos Izpisua Belmonte, a Spanish biologist who has spent years pioneering innovations in developmental biology, regenerative medicine and aging research at the Salk Institute.

Continue reading “Prevent Aging within 20 Years? — Altos Labs’ Cellular Reprogramming Excitement” | >