Summary: A new study will investigate the genetic and biological mysteries of extreme longevity and healthy aging.
Source: american federation for aging research.
Decades of research will be aided by the results of a study launched today – the most ambitious ever conducted to uncover and understand the genetic and biological mysteries of exceptional longevity and healthy aging.
Transhumanists are redefining what it means to be human. This talk takes a deeper look at the movement and its implications for the future. About this event.
From bionic eyes to designing new senses and extending life expectancy, transhumanists are redefining what it means to be human. This talk takes a deeper look at the movement and its implications for the future of humanity.
Transhumanism is the belief that human beings are destined to transcend their mortal flesh through technology. From bionic eyes to designing new senses and extending life expectancy, transhumanists are redefining what it means to be human.
The profiles of transhumans are as diverse as its application. From artists and CEOs to academics and bedroom hackers, the transhumanist movement raises some important questions for us all.
While we love the efficiency and connectivity technology provides, can we embrace a future where it goes beyond our environment and enters our bodies and minds? Could we reach a point where we gift friends and family cognitive implants and new senses? If we are able to defy death, what are the implications for the meaning of life? And, most importantly, will this evolution divide or unite us?
The common longevity supplement NMN has recently been banned by the FDA for several reasons which have sent ripples through the longevity, sparking outrage and several concerns as to where the longevity industry is heading.
Aging is a complex process that can lead to chronic diseases such as diabetes, cardiovascular disorders, muscular degeneration, atherosclerosis and neurodegeneration, and it is currently one of the major scientific concerns in the field of medicine [1].
Several strategies have been developed to date for the promotion of healthy aging and an increase in the duration of life. One of the recent strategies that can decrease the deleterious impact of aging and increase the regenerative property at the cellular level is cellular reprogramming.
Cellular reprogramming can convert a somatic cell into an induced pluripotent stem cell (iPSC). It not only helps to restore tissue and organ function but also helps to determine cell fate. This, in turn, helps in the maintenance of cellular identity through the expression of cell type-specific genes and suppression of lineage-inappropriate genes [2].
A bit concerning cellular reprogramming after a few minutes, and stating a goal just before 7:00 a stated goal of reversing aging across the entire human.
“There are no hard limits imposed by biology or by physics that says that we can’t live better longer,” Kristen Fortney, CEO of San Francisco-based BioAge Labs, told the outlet. Focused on discerning the markers of aging, BioAge Labs is using large amounts of biobank blood and tissue samples to do so.
The company has already found a drug target that slows aging-linked muscle loss in mice.
“There is a protein called apelin that circulates in the blood, and we saw that middle-aged people with higher levels of apelin in their blood were living longer, with better muscle function and better cognitive function as they age,” Fortney said, according to Express.
A new study in an animal model of aging indicates a potential reason for why women who have early menopause or other genetic conditions affecting the reproductive system are more prone to develop cardiovascular disease, diabetes, and dementia.
The new study, led by researchers from the University of Pittsburgh and UPMC and published in the journal Aging Cell, found that disrupting a process called meiosis in C. elegans reproductive cells caused a decline in the worms’ health and triggered an accelerated aging gene signature similar to that of aging humans.
“This study is exciting because it’s the first direct evidence that manipulating the health of reproductive cells leads to premature aging and a decline in healthspan,” said senior author Arjumand Ghazi, Ph.D., associate professor of pediatrics, developmental biology, and cell biology and physiology at Pitt and UPMC Children’s Hospital of Pittsburgh. “The implications of this finding are profound: It suggests that the status of the reproductive system is important not simply to produce children, but also for overall health.”
People affected by the lethal glioblastoma cancer only live for 12–18 months after diagnosis.
A global trial that began in 2007 has confirmed that a vaccine for the treatment of the most lethal brain cancer can give patients years of extended life.
Glioblastoma is not only the most common form of brain cancer but is also one of the deadliest. People affected by the disease only live just 12–18 months after the diagnosis, or even less.
Now, thanks to the vaccine DCVax, some 2,500 people who are diagnosed with deadly cancer in the UK could be benefitted.