Summary: Researchers have developed a new ophthalmological device that can detect degenerative visual problems such as age-related macular degeneration long before the onset of the first symptoms.
Source: EPFL
Researchers at an EPFL lab have developed an ophthalmological device that can be used to diagnose some degenerative eye disorders long before the onset of the first symptoms. In early clinical trials, the prototype was shown to produce images with a sufficient degree of precision in just five seconds.
When in 2015, Eileen Brown looked at the ETER9 Project (crazy for many, visionary for few) and wrote an interesting article for ZDNET with the title “New social network ETER9 brings AI to your interactions”, it ensured a worldwide projection of something the world was not expecting.
Someone, in a lost world (outside the United States), was risking, with everything he had in his possession (very little or less than nothing), a vision worthy of the American dream. At that time, Facebook was already beginning to annoy the cleaner minds that were looking for a difference and a more innovative world.
Today, after that test bench, we see that Facebook (Meta or whatever) is nothing but an illusion, or, I dare say, a big disappointment. No, no, no! I am not now bad-mouthing Facebook just because I have a project in hand that is seen as a potential competitor.
I was even a big fan of the “original” Facebook; but then I realized, it took me a few years, that Mark Zuckerberg is nothing more than a simple kid, now a man, who against everything and everyone, gave in to whims. Of him, initially, and now, perforce, of what his big investors, deluded by himself, of what his “metaverse” would be.
In the style of Sleeping Beauty, Tardigrades, the adorable, tiny animals that can withstand extreme environments and are also known as “water bears,” can withstand freezing without losing their vitality. Despite harsh environmental conditions, tardigrades are very adaptable. According to Ralph Schill, a professor at the University of Stuttgart, anhydrobiotic (dry) tardigrades can survive for many years without absorbing water. In a frozen state, there was no clear indication of whether aging increased or decreased. It turns out that frozen tardigrades don’t age.
Water bears, also known as tardigrades, are nematodes. They have the same gait as bears, but that’s about the only thing that connects them to bears. As a result of their adaptability to rapidly changing environmental conditions, tardigrades, which are barely one millimeter in size, can freeze in extreme cold and dry out in extreme heat. Rather than dying, Schill explains that they fall into a deep sleep. A cell organism experiences different types of stress when it freezes or dries out. Despite this, tardigrades are equally capable of surviving both extremes of heat and cold. No obvious signs of life can be seen on them. In this state of rest, the animal’s internal clock might be slowed down, which raises the question of whether it ages.
Schill and his team investigated the aging process of dried tardigrades several years ago, which waited in their habitat for rain for many years. Grimm brothers’ fairytales depict a princess who is deeply asleep. A young prince kisses her 100 years later, and she awakes looking as beautiful and young as ever. In a dried state, tardigrades are the same, and therefore this hypothesis is called the “Sleeping Beauty” hypothesis. Schill explains that the internal clock stops during inactivity and resumes once the organism has been reactivated. Accordingly, the researcher explained that tardigrades, whose lifespan usually lasts only a few months without rest, can survive for decades.
Cryo-electron microscopy structures of skeletal F-actin show solvent-driven rearrangements governing actin filament assembly and aging with potential application in design of drugs and small molecules for imaging and therapy.
Werner Syndrome and Hutchinson Gilford Progeria Syndrome are two examples of the rare genetic disorders known as progeroid syndromes that cause signs of premature aging in children and young adults. Patients with progeroid syndromes have pathologies and symptoms that are often linked to aging, including osteoporosis, cataracts, heart disease, and type II diabetes.
This aging is characterized by the gradual loss of nuclear architecture and an underlying tissue-specific genetic program, but the causes are unclear. Scientists have discovered a potential new target for treating these syndromes by preventing nuclear architecture loss.
Dr. Peter Fedichev, Ph.D. is the CEO of Gero (https://gero.ai/), a biotech company focused on hacking complex diseases, including aging, with AI for novel drug discovery, as well as digital biomarkers.
Gero’s models originate from the physics of complex dynamic systems, combining the potential of deep neural networks with the physical models to study dynamical processes and understand what drives diseases.
Dr. Fedichev has a background in biophysics, bioinformatics and condensed matter physics, earning his Ph.D. from the University of Amsterdam, and he conducted research at FOM Institute AMOLF (part of the institutes organization of the Dutch Research Council of Netherlands) and the University of Innsbruck.
To date, Dr Fedichev has published over 70 papers covering his research on physics, biophysics and aging biology.
Turtles, unlike humans, do not continue to age once their bodies reach adulthood because they are “negligibly senescent.” It is theoretically possible for them to live indefinitely, although it is unlikely to happen in actuality. They will eventually die of injury, predation, or sickness. It has been documented that tortoises and their cousins, turtles, can live for up to two hundred years without showing any signs of aging. A turtle that is a hundred years old can experience the same feelings of youth as a tortoise that is thirty years old. This enviable trait may be found in both fish and amphibians. The idea of aging terrifies humans, and it is understandable why. Nobody wants to age slowly and painfully into a state of ill health and old age where death appears preferable to life. However, not everyone thinks this way. There are others who desire to live longer, perhaps even indefinitely. And while a life without aging might sound like something that could only be found in the pages of a fantasy story, research in the field of science suggests that this possibility is very much within our reach.
In today’s video we look at Live until 200 YRS OLD!! Scientific cures for “The Aging Disease!” ~ Healthicity…Keep watching to see aging, the ageing, the healthy aging, is an aging expert, is aging slower, and reverse aging, fighting aging, how to fight aging, anti aging, aging wired, wired aging, aging matters, aging questions, how to stop aging, science of aging, ageing research, anti aging, aging tech support, slow aging, aging women, what is aging, allure aging, aging beauty, active aging, disrupt aging, aging support, aging science, decoding aging, future of aging, aging with grace.
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Inspired by the science of slowing down aging | WIRED
Inspired by Is Aging Reversible? A Scientific Look with David Sinclair | David Sinclair | TEDxBoston.
Extending the limit of the human lifespan. The first immortal human has already been born. “The first human to live to 1,000 has already been born” – Dr. Aubrey de Grey. How far are we in understanding aging and death? Do we have to age or is it a matter of a choice? What is the future of immortality? Is it possible to be immortal and if yes — how far are we in implementing medical treatment and technology that can forestall this natural process we have always thought “is just how life is”. In this video I am reviewing the cutting-edge technologies and the pioneers in the field of extending life expectancy and reaching immortality eventually. Hint: is it closer than you might imagine!
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