Cryonics is one of the most misunderstood ideas in science today: most people think it means “freezing dead people.” It doesn’t. Follow Tomorrow.bio to understand what cryopreservation actually is, how it works, and why a growing number of healthy people are choosing to sign up for it long before they need it. Thinking seriously about cryopreservation? We created a free guide covering the process, costs, funding, and important planning decisions: [ https://www.tomorrow.bio/tools/cryoguide ] 🫀ABOUT THIS VIDEO Part 3 of Cryonics A-Z is here. We’re covering the ethics behind cryopreservation, the current laws and regulations, what the future could look like, and the myths that just won’t die (pun intended). If you’ve ever wondered what’s actually true about cryonics, and what’s just noise, this one’s for you. 🔎 CHAPTERS [ 00:00 ] – Introduction [ 00:30 ] – Ethics of cryopreservation [ 07:56 ] – Do we freeze people? [ 10:01 ] – We just want to make money [ 12:53 ] – What about the future? [ 15:18 ] – How to deal with overpopulation [ 18:52 ] – Stagnation [ 20:47 ] – Cryonics & Religion [ 22:34 ] – Law & Regulation [ 30:41 ] – Outro 🔗 LINKS.
Category: life extension – Page 17
Blocking a mitochondrial transporter may curb inflammation from ‘zombie’ cells without killing them
Researchers have uncovered a previously unknown mechanism that helps aging cells drive the chronic inflammation linked to many age-related diseases. The findings reveal how dysfunctional mitochondria—the cell’s energy-producing structures—work with the cell’s epigenetic machinery to switch on inflammatory genes, opening the door to a new therapeutic approach for promoting healthier aging.
The study, published in Nature, builds on years of research showing that senescent, or “zombie,” cells accumulate with age. While these cells no longer divide, they remain metabolically active and release a cocktail of inflammatory molecules known as the senescence-associated secretory phenotype, or SASP.
This persistent inflammation is thought to contribute to frailty, cardiovascular disease, cancer, neurodegeneration and other disorders of aging.
Scientists identify new mitochondrial pathway linked to harmful inflammation in aging
ROCHESTER, Minn. — Researchers have uncovered a previously unknown mechanism that helps aging cells drive the chronic inflammation linked to many age-related diseases. The findings reveal how dysfunctional mitochondria — the cell’s energy-producing structures — work with the cell’s epigenetic machinery to switch on inflammatory genes, opening the door to a new therapeutic approach for
One overlooked sign of aging may reveal dementia risk years earlier
Frailty was assessed using a frailty index, which takes into account a wide range of health and functional measures. Researchers classified participants with scores of 0.25 or higher as frail.
The results showed that frailty was associated with developing dementia at a younger age. Overall, frail individuals received a dementia diagnosis approximately two to three years earlier than those who were not frail.
“The best approach to preventing or reducing frailty is a combination of regular physical activity, particularly strength training, and a diet that ensures adequate protein intake,” study co-author Dr. David Ward, a research fellow in aging and geriatric medicine at the Centre for Health Services Research, Faculty of Medicine at the University of Queensland, told Newsweek.
Brain Scans Reveal Which Disorders May Accelerate Brain Aging
Accelerated brain aging was associated with dementia, addiction, and psychiatric disorders such as schizophrenia.
A brain scan can make a person’s brain appear older or younger than their actual age. Across tens of thousands of scans, researchers found that dementia, mild cognitive impairment, alcohol addiction, and psychiatric conditions such as schizophrenia were associated with older-appearing brains, although each condition showed a different anatomical pattern.
The findings were reported in the open-access journal PLOS Medicine by Shile Qi of the Nanjing University of Aeronautics and Astronautics in China and colleagues.
UC Berkeley Conference on Aging and Longevity: Gregory Fahy, Wei-Wu He, and Andreas Stahl
On Sunday, July 19, 2026, at 1 p.m. U.S. Pacific Time, watch the third compilation stream, consisting of three additional presentations from the May 3, 2026, sessions at the University of California, Berkeley Conference on Aging and Longevity (BerkeleyCAL), hosted by Professor Steven A. Garan, Director of Bioinformatics at the Center for Research and Education on Aging.
These presentations delve into cutting-edge science, including actual human trials on rejuvenation, efforts to improve human longevity through genetic screening, and models of senescence at the cellular level. They are delivered by renowned longevity researchers Gregory Fahy, Wei-Wu He, and Andreas Stahl. The presentations include question-and-answer sessions, including questions posed by U.S. Transhumanist Party Chairman Gennady Stolyarov II to Andreas Stahl.
Dr. Greg Fahy of Intervene Immune presents evidence that thymic involution—the age-related decline of the thymus gland—is a primary driver of immune failure and various age-related diseases, including cancer and cardiovascular issues. To address this, he details the multiple TRIIM clinical trials in small cohorts of human patients, which successfully demonstrate that a combination of growth hormone, DHEA, and metformin can safely regenerate functional thymic tissue and rejuvenate the immune system.
Dr. Wei-Wu He of Human Longevity, Inc., emphasizes the critical importance of whole-genome sequencing for personalized longevity and healthcare, noting that genetics account for approximately 50–55% of an individual’s healthspan and lifespan. Reflecting on the legacy of Human Longevity, Inc. founder Dr. J. Craig Venter (1946−2026), Dr. He’s presentation advocates for utilizing genomic data alongside AI and advanced clinical diagnostics to shift from reactive sick care to proactive, data-driven prevention. Dr. He highlights new, accessible initiatives to bring comprehensive genomic analysis and proteomic testing to the public to help individuals identify and manage their unique health risks.
Dr. Andreas Stahl of UC Berkeley presents a microphysiological \.
Digital Immortality — Backing Up the Human Soul
Could digital immortality really save you, or just create a convincing copy? We explore mind uploading, backups, identity, and whether survival means continuity… or redundancy.
Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthur.
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/ discord Credits: Digital Immortality — Backing Up the Human Soul Written, Produced & Narrated by: Isaac Arthur Select imagery/video supplied by Getty Images Chapters 0:00 Intro 1:43 What Are We Actually Backing Up? 7:36 The Roads to Immortality: Uploading vs Gradualism 13:56 The Copy Problem: You’re Still in the Chair 16:38 Practical Identity: What Do You Actually Do About It? 19:12 Why We’d Build Backups Anyway 22:00 Oldest & Newest 23:12 Failure Modes, Uses, and the Meaning of Survival.
Watch my exclusive video Colonizing Ocean Worlds: https://nebula.tv/videos/isaacarthur–…
🛒 SFIA Merchandise: https://isaac-arthur-shop.fourthwall…
🌐 Visit our Website: http://www.isaacarthur.net.
❤️ Support us on Patreon: / isaacarthur.
⭐ Support us on Subscribestar: https://www.subscribestar.com/isaac-a…
👥 Facebook Group: / 1583992725237264
📣 Reddit Community: / isaacarthur.
🐦 Follow on Twitter / X: / isaac_a_arthur.
💬 SFIA Discord Server: / discord.
Credits:
Digital Immortality — Backing Up the Human Soul.
Written, Produced & Narrated by: Isaac Arthur.
Select imagery/video supplied by Getty Images.
Chapters.
0:00 Intro.
1:43 What Are We Actually Backing Up?
7:36 The Roads to Immortality: Uploading vs Gradualism.
13:56 The Copy Problem: You’re Still in the Chair.
16:38 Practical Identity: What Do You Actually Do About It?
19:12 Why We’d Build Backups Anyway.
22:00 Oldest & Newest.
23:12 Failure Modes, Uses, and the Meaning of Survival.
Let’s talk about my clone…
He makes sure to tell people he did not make embryos.
Friends, I did NOT create a human clone. What I did create are induced pluripotent stem cells (iPSCs) — cells that can potentially become many different cell types and may one day help repair the body.
It’s one of the most promising technologies in regenerative medicine, and is already being explored in clinical research.
The science is fascinating, the ethical questions are important, and both deserve thoughtful discussion.