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Archive for the ‘life extension’ category: Page 140

Mar 15, 2022

The conserved mitochondrial gene distribution in relatives of Turritopsis nutricula, an immortal jellyfish

Posted by in categories: biotech/medical, genetics, life extension

Immortal jellyfish could actually be the key to immortality and regeneration. This article talks more in depth of its importance in the search of immortality.


Turritopsis nutricula (T. nutricula) is the one of the known reported organisms that can revert its life cycle to the polyp stage even after becoming sexually mature, defining itself as the only immortal organism in the animal kingdom. Therefore, the animal is having prime importance in basic biological, aging, and biomedical researches. However, till date, the genome of this organism has not been sequenced and even there is no molecular phylogenetic study to reveal its close relatives. Here, using phylogenetic analysis based on available 16s rRNA gene and protein sequences of Cytochrome oxidase subunit-I (COI or COX1) of T. nutricula, we have predicted the closest relatives of the organism. While we found Nemopsis bachei could be closest organism based on COX1 gene sequence; T. dohrnii may be designated as the closest taxon to T. nutricula based on rRNA. Moreover, we have figured out four species that showed similar root distance based on COX1 protein sequence.

Keywords: Turritopsis nutricula, immortal jellyfish, trans-differentiation, phylogeny, relativeness.

Continue reading “The conserved mitochondrial gene distribution in relatives of Turritopsis nutricula, an immortal jellyfish” »

Mar 15, 2022

Scientists Develop New Anti-Aging CRISPR-Based Gene Therapy

Posted by in categories: biotech/medical, life extension

Circa 2021 😃


CRISPR-induced KAT7 gene inactivation rejuvenates prematurely aging human cells and mice and promotes longevity.

Mar 13, 2022

If You Could, Would You Live Forever? David Sinclair on Extending Lifespan

Posted by in category: life extension

This starts with Tyson’s deathism quote, but I’m still a fan. I do wonder if he’ll take a treatment when he sees everyone else rejuvenating around him.

Mar 11, 2022

Bionic eyes: How tech is replacing lost vision

Posted by in categories: cyborgs, life extension, neuroscience, transhumanism

This technology has to translate images into something the human brain can understand. Click the numbers in the interactive image below to find read about how this works.

There are a whole range of conditions, some which are picked up due to the aging process and others which may be inherited, that can cause sight deterioration.

Bionic eyes work by ‘filling in the blanks’ between what the retina perceives and how it is processed in the brain’s visual cortex, that breakdown occurs in conditions which impact the retina. It is largely these conditions which bionic eyes could help treat.

Mar 11, 2022

Scientists “Elated”

Posted by in categories: biotech/medical, genetics, life extension

An international team of researchers claim to have slowed the signs of aging in mice by resetting their cells to younger states, using a genetic treatment.

To the scientists, The Guardian reports, it’s a breakthrough in cell regeneration and therapeutic medicine that doesn’t seem to cause any unexpected issues in mice.

“We are elated that we can use this approach across the life span to slow down aging in normal animals,” said Juan Carlos Izpisua Belmonte, Salk Institute professor and co-corresponding author of a new study published in the journal Nature Aging, in a statement. “The technique is both safe and effective in mice.”

Mar 11, 2022

Topical tissue nano-transfection mediates non-viral stroma reprogramming and rescue

Posted by in categories: biotech/medical, life extension, nanotechnology

Circa 2017


Arrayed nanochannels can be used to controllably transfect and reprogram tissues in vivo for applications in regenerative medicine and cell-based therapies.

Mar 11, 2022

Dr. Kara Spiller, PhD — Immunomodulatory Biomaterials In Regenerative Medicine — Drexel University

Posted by in categories: bioengineering, biotech/medical, education, life extension

Immunomodulatory Biomaterials In Regenerative Medicine — Dr. Kara Spiller-Geisler, Ph.D., Drexel University School of Biomedical Engineering, Science and Health Systems.


Dr. Kara Spiller, PhD (https://drexel.edu/biomed/faculty/core/SpillerKara/) is Associate Professor in the Biomaterials and Regenerative Medicine Laboratory at Drexel University, in Philadelphia.

Continue reading “Dr. Kara Spiller, PhD — Immunomodulatory Biomaterials In Regenerative Medicine — Drexel University” »

Mar 11, 2022

Aging reversed in middle-aged and elderly mice

Posted by in categories: biotech/medical, life extension

A new cellular rejuvenation therapy is reported by scientists at the Salk Institute, which can reverse aspects of aging in mice, without causing cancer or other health problems.

Mar 11, 2022

Juan Carlos Izpisua: ‘Within two decades, we will be able to prevent aging’

Posted by in category: life extension

The leading Spanish scientist talks to EL PAÍS about his new role at the secretive multinational Altos Labs, where he hopes to use cellular rejuvenation to reverse illness and cell deterioration.

Mar 11, 2022

CRISPR On-Off Switch Will Help Unlock the Secrets of Our Immune System

Posted by in categories: biotech/medical, genetics, life extension

Can we turn up—or dial down—their fervor by tweaking their genes?

Enter a new kind of CRISPR. Known mostly as a multi-tool to cut, snip, edit, or otherwise kneecap an existing gene, this version—dubbed CRISPRa—forcibly turns genes on. Optimized by scientists at Gladstone Institutes and UC San Francisco, the tool is counterbalanced by CRISPRi—“i” for “interference,” which, you guessed it, interferes with the gene’s expression.

Though previously used in immortal cells grown in labs, this is the first time these CRISPR tools are rejiggered for cells extracted from our bodies. Together, the tools simultaneously screened nearly 20,000 genes in T cells isolated from humans, building a massive genetic translator—from genes to function—that maps how individual genes influence T cells.