Lifeboat Foundation

ATLANTA — Three years after being named the first-ever co-valedictorians at West Forsyth High School, the Kashlan triplets graduated from Georgia Tech at 18-years-old.

Adam, Zane, and Rommi Kashlan earned neuroscience degrees with minors in health and medical sciences. They completed their degrees a year early and with honors. The trio will head to Boston to work and conduct research at Harvard Medical School.

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Altos Labs just redefined big in biotech. Where to start? The $3 billion in investor support? The C-suite staffed by storied leaders—Barron, Bishop, Klausner—identifiable by one name? Or the wildly ambitious plan to reverse disease for patients of any age? Altos is all that and more.

Early details of Altos leaked out last year when MIT Technology Review reported Jeff Bezos had invested to support development of technology that could “revitalize entire animal bodies, ultimately prolonging human life.” The official reveal fleshes out the vision and grounds the technology in the context of the nearer-term opportunities it presents to improve human health.

“It’s clear from work by Shinya Yamanaka, and many others since his initial discoveries, that cells have the ability to rejuvenate, resetting their epigenetic clocks and erasing damage from a myriad of stressors. These insights, combined with major advances in a number of transformative technologies, inspired Altos to reimagine medical treatments where reversing disease for patients of any age is possible,” Hal Barron, M.D., said in a statement.

Sensing systems are becoming prevalent in many areas of our lives, such as in ambient-assisted health care, autonomous vehicles, and touchless human-computer interaction. However, these systems often lack intelligence: they tend to gather all available information, even if it is not relevant. This can lead not only to privacy infringements but also to wasted time, energy, and computational resources during data processing.

To address this problem, researchers from the French CNRS came up with a concept for intelligent electromagnetic sensing, which uses machine-learning techniques to generate learned illumination patterns so as to pre-select relevant details during the measurement process. A programmable metasurface is configured to generate the learned patterns, performing high-accuracy sensing (e.g., posture recognition) with a remarkably reduced number of measurements.

But measurement processes in realistic applications are inevitably subject to a variety of noise. Noise fundamentally accompanies any measurement. The signal-to–noise ratio can be particularly low in indoor environments where the radiated electromagnetic signals must be kept weak.

The Covid omicron XBB.1.5 variant is rapidly becoming dominant in the U.S. because it is highly immune evasive and appears more effective at binding to cells than related subvariants, scientists say.

XBB.1.5 now represents about 41% of new cases nationwide in the U.S., nearly doubling in prevalence over the past week, according to the data published Friday by the Centers for Disease Control and Prevention. The subvariant more than doubled as a share of cases every week through Dec. 24. In the past week, it nearly doubled from 21.7% prevalence.

Scientists and public health officials have been closely monitoring the XBB subvariant family for months because the strains have many mutations that could render the Covid-19 vaccines, including the omicron boosters, less effective and cause even more breakthrough infections.

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A new human study shows that a collagen supplement significantly reduced wrinkles around the eyes after only 12 weeks of treatment.

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The devastating 2014–2016 Ebola epidemic in West Africa prompted changes in the way the world responds to outbreaks and other health emergencies. Here are eight things that are being done differently in the response to the Ebola outbreak in the Democratic Republic of the Congo (DRC).

In a recent study published in Cell, researchers used a multi-omics approach to profile the gut microbiomes and metabolomes of mothers and infants to determine the vertical and horizontal transmission of bacterial species and strains as well as individual genes and understand the dynamics of the gut microbiome assembly that shape the development of the infant before and after birth.

The vertical transmission of gut bacteria from mother to fetus during pregnancy and the horizontal transfer of microbes through breast milk plays a vital role in the physical and cognitive development of the infant long after birth. Studies have shown associations between the gut microbiota composition of breastmilk and the development of the infant’s immune system, as well as autoimmune conditions and allergies. Furthermore, allergies and autoimmune disorders have also been linked to exogenous proteins in infant formula.

Metabolites produced by gut microbiota are also associated with the infant’s cognitive development. However, the development of gut microbiomes and metabolomes in the perinatal stage and their role in infant development remains unclear.

Although the toxicity of graphene‐based nanomaterials on human health has been extensively studied, their impact on the microbiome remains poorly understood. Using zebrafish as a model, we show that graphene oxide modulates the immune system in a microbiome‐dependent manner through a mechanism mediated by the aryl hydrocarbon receptor. The study suggests an interplay among graphene‐based nanomaterials, microbiome and innate immune system.