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Groundbreaking New Research Reveals How Working Out Could Prevent Dementia

A study confirms the positive effects of exercise on insulinInsulin is a hormone produced by the pancreas, crucial for regulating blood glucose levels. It helps cells in the body absorb glucose from the bloodstream and convert it into energy or store it for future use. Insulin production and action are essential for maintaining stable blood sugar levels. In people with diabetes, the body either does not produce enough insulin (Type 1 diabetes) or cannot effectively use the insulin it does produce (Type 2 diabetes), leading to elevated levels of glucose in the blood. This can cause various health complications over time, including heart disease, kidney damage, and nerve dysfunction. Insulin therapy, where insulin is administered through injections or an insulin pump, is a common treatment for managing diabetes, particularly Type 1. The discovery of insulin in 1921 by Frederick Banting and Charles Best was a landmark in medical science, transforming diabetes from a fatal disease to a manageable condition. tabindex=0 insulin signaling proteins in the brain.

Fatty Muscles Raise the Risk of Serious Heart Disease Regardless of Overall Body Weight, study shows

People with pockets of fat hidden inside their muscles are at a higher risk of dying or being hospitalized from a heartattack or heart failure, regardless of their body mass index, according to research published in the European Heart Journal.

This ‘intermuscular’ fat is highly prized in beef steaks for cooking. However, little is known about this type of body fat in humans, and its impact on health. This is the first study to comprehensively investigate the effects of fatty muscles on heart disease.

The new finding adds evidence that existing measures, such as body mass index or waist circumference, are not adequate to evaluate the risk of heart disease accurately for all people.

Muscle Strength and Cardiorespiratory Health Correlate to Reduced Mortality in Cancer Survivors

Physical fitness is typically associated with health benefits, and we generally consider exercise good. Many studies have shown that this relates to cancer, where exercise and maintaining a healthy weight can reduce the risk of developing cancer. Studies have shown that obesity raises the risk of mortality in cancer patients.

Data recently published in the British Journal of Sports Medicine suggests that staying fit could reduce the risk of dying from cancer. The study looked at two different readouts for fitness: muscle strength and cardiorespiratory fitness (CRF).

The researchers undertook a comprehensive review and meta-analysis by examining peer-reviewed studies published before August 2023. The analysis included 42 studies encompassing over 46,000 patients.

SLS NASA’s Moon Rocket Canceled?

Has NASA canceled the SLS moon rocket? Will the Artemis Program be canceled too? Can we still beat China to the moon? See why that is vital and my role in helping to establish both the commercial space and SLS programs.

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Radio Signal from Planet YZ Ceti b

Earth sized planet causes parent star to emit radio signals indicating presence of a magnetic field and potential for live elsewhere in the cosmos.

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Global study finds dramatic disparities in progress toward Sustainable Development Goals

The Sustainable Development Goals (SDGs) constitute the leading global framework for achieving human progress, economic prosperity, and planetary health. This framework emphasizes issues such as public health, education for all, gender equality, zero hunger, adoption of clean and renewable energy, and biodiversity conservation. Yet, despite this comprehensive agenda, questions remain about how different nations navigate their own paths toward these goals.

A recent study, published in Nature Communications provides insights into the trajectories of 166 countries as they have worked toward the SDGs over the past two decades.

By applying and the Product Space methodology, commonly used in the field of complexity economics, the researchers constructed the “SDG Space of Nations.” The elaborate model shows that countries do not simply march in lockstep toward sustainable development; instead, they cluster into distinctive groups, each with its own strengths and specializations, sometimes quite unexpected.

Asteroid Impact 2032 — Asteroid 2024 YR4

Almost 2% chance for catastrophic impact in 7 years? What should we do?


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Indonesia’s new capital could become a hot spot for infectious diseases

A 2020 assessment of IKN by the National Planning and Development Agency highlighted the risks, citing data including the abundance of disease-carrying mosquitoes. At least two construction workers caught malaria in 2022 while at the site, according to the Ministry of Health. Last year, 54 cases were reported there, but the ministry claimed the patients were infected elsewhere. Although the construction authority has taken some control measures, such as handing out mosquito nets to workers, it’s not well-equipped for the job, says Mirza Buana, a legal scholar at Lambung Mangkurat University in South Kalimantan: “It has all the authorities but no capabilities.” The agency has shifted most of the tasks—such as vector control and screening workers entering or leaving IKN—to district health officials, who have struggled to keep up.

Surendra is particularly worried about the potential spread of P. knowlesi, a parasite first discovered in the 1930s. It emerged as a public health threat in the early 2000s, in areas in the Malaysian part of Borneo where forests were cleared for oil palm plantations. It has since been identified in many Southeast Asian countries.

P. knowlesi primarily infects long-tailed macaques, highly adaptable monkeys that thrive at the forest edge, and is spread by forest-dwelling Anopheles mosquitoes that occasionally bite humans as well. People working in or near the forest, including hunters and loggers, are at the highest risk. Because it has an animal reservoir, the disease is impossible to eliminate completely. Mosquitoes don’t transmit P. knowlesi between people—or very poorly—but some scientists worry that could change.

Scientists recode the genome for programmable synthetic proteins

Synthetic biologists from Yale were able to re-write the genetic code of an organism—a novel genomically recoded organism (GRO) with one stop codon—using a cellular platform that they developed enabling the production of new classes of synthetic proteins. These synthetic proteins, researchers say, offer the promise of innumerable medical and industrial applications that can benefit society and human health.

The creation of the landmark GRO, known as “Ochre”—which fully compresses redundant, or “degenerate” codons, into a single codon—is described in a new study published in the journal Nature. A codon is a sequence of three nucleotides in DNA or RNA that codes for a specific amino acid, which serves as the biochemical building blocks for proteins.

“This research allows us to ask fundamental questions about the malleability of genetic codes,” said Farren Isaacs, professor of molecular, cellular and at Yale School of Medicine and of biomedical engineering at Yale’s Faculty of Arts and Sciences, who is co-senior author of the paper. “It also demonstrates the ability to engineer the genetic code to endow multi-functionality into proteins and usher in a new era of programmable biotherapeutics and biomaterials.”

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