Lifeboat Foundation

Telegenomics provider Genome Medical has raised $23 million to help scale up its “last-mile” patient counseling services for healthcare systems and individuals across the U.S.

The company also plans to expand its team of clinical genomics specialists as well as continue the development of its delivery platform. The series B round brings Genome Medical’s fundraising total up to $46 million since its 2016 founding.

The latest financing was led by Echo Health Ventures, a collaboration between Cambia Health Solutions and Mosaic Health Solutions. Other new backers included LRVHealth, Casdin Capital, Perceptive Advisors, Manatt Venture Fund and Dreamers Fund.

Continue reading “Genome Medical nets $23M to grow its telegenomics service platform” »

We may like to think that what we do in our daily lives only affects ourselves and perhaps a few people around us, but the increasingly active field of scientific inquiry called epigenetics suggests that life experiences like what we eat and the environments we expose ourselves to can influence the health and development of our kids and the generations beyond them.

Studies of both humans and animals have suggested that a father’s experiences can be transmitted across generations, but the mechanism for this epigentic inheritance hasn’t quite been clear.

New research published Wednesday in Nature Communications details how Susan Strome’s lab at UC Santa Cruz observed the transmission of epigenetic markers in the sperm of the small roundworm Caenorhabditis elegans.

Continue reading “Epigenetic ‘Memories’ That Could Pass On A Father’s Life Experiences Seen In Worm Sperm” »

Is a new phone on your holiday shopping list? A “radical” technology being developed at Purdue University that’s making smartphones and other electronic devices more bendable could help save lives one day soon through better health monitoring.

Recent research in the field of mind-body medicine shows there’s a lot more to health than what you eat, and most of it has to do with your mind.

A team of researchers affiliated with the Broad Institute of MIT and Harvard, MIT and the National Institutes of Health has found that CRISPR-associated transposons can be used to insert custom genes into DNA without cutting it. In their paper published in the journal Science, the group describes their new gene-editing technique and how well it worked when tested in a bacterial genome.

The CRISPR gene editing technique has made headlines in recent years due to its potential for treating hereditary diseases. Unfortunately, despite much research surrounding the technique, it is still not a viable option for use on human patients. This is because the technique is error-prone—when snipping strands of DNA, CRISPR sometimes cuts off-target DNA as well, leading to unintended and unpredictable consequences (and sometimes cancerous tumors). In this new effort, the researchers have found a way to use CRISPR in conjunction with another protein to edit a strand of DNA without cutting it—they are calling it CRISPR-associated transposase (CAST).

Prior research has shown that certain pieces of DNA called transposons are, for unknown reasons, able to reposition themselves in a genome spontaneously—for this reason, they have come to be known as jumping genes. Not long after they were discovered, researchers noted that they might be used for gene editing. This is what the researchers did in the new study. They associated a transposon called Tn7 with the Cas12 enzyme used with CRISPR to edit a section of a bacterial genome. In practice, CRISPR led the Tn7 transposon to the target location in the genome—at that point, the transposon inserted itself into the genome without cutting it.

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The growing interest in cannabis and cannabis-derived products has sparked uncertainty and concern over the industry’s lack of regulations. On Thursday, the FDA held a hearing that looked deeper into the science and safety concerns that surround marijuana and CBD.

Medical Marijuana Inc (MJNA) CEO Stuart Titus is optimistic about the effects that cannabis-derived products have on humans.

“We have a very large self-regulatory system in our human bodies called the internal or the endogenous cannabinoid system,” Titus told YFi AM (video above). “And basically since cannabis has been removed from our diets for the past 80-plus years, many of us are cannabinoid deficient, and thus we start taking a nice supplementary-size serving of CBD. Many people are moving to a much higher level of overall health and wellness.”

Continue reading “Marijuana CEO: ‘Many of us are cannabinoid deficient’” »

French scientists find common mental health drugs combat rapid and sometimes deadly brain infection. Andrew Masterson reports.