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Gene that causes deadliest brain tumor also causes childhood cancers, new research shows

A gene that University of Virginia (UVA) Health researchers have discovered is responsible for the deadliest type of brain tumor is also responsible for two forms of childhood cancer, the scientists have found.

The new discovery may open the door to the first targeted treatments for two types of , a cancer of the soft tissue that primarily strikes young children.

The gene may also play an important role in other cancers that form in muscle, fat, nerves and other connective tissues in both children and adults, the research suggests.

DeepMind’s AI has now catalogued every protein known to science

In late 2020, Alphabet’s DeepMind division unveiled its novel protein fold prediction algorithm, AlphaFold, and helped solve a scientific quandary that had stumped researchers for half a century. In the year since its beta release, half a million scientists from around the world have accessed the AI system’s results and cited them in their own studies more than 4,000 times. On Thursday, DeepMind announced that it is increasing that access even further by radically expanding its publicly-available AlphaFold Protein Structure Database (AlphaFoldDB) — from 1 million entries to 200 million entries.

Alphabet partnered with EMBL’s European Bioinformatics Institute (EMBL-EBI) for this undertaking, which covers proteins from across the kingdoms of life — animal, plant, fungi, bacteria and others. The results can be viewed on the UniProt, Ensembl, and OpenTargets websites or downloaded individually via GitHub, “for the human proteome and for the proteomes of 47 other key organisms important in research and global health,” per the AlphaFold website.

“AlphaFold is the singular and momentous advance in life science that demonstrates the power of AI,” Eric Topol, Founder and Director of the Scripps Research Translational Institute, siad in a press statement Thursday. “Determining the 3D structure of a protein used to take many months or years, it now takes seconds. AlphaFold has already accelerated and enabled massive discoveries, including cracking the structure of the nuclear pore complex. And with this new addition of structures illuminating nearly the entire protein universe, we can expect more biological mysteries to be solved each day.”

New hardware offers faster computation for artificial intelligence, with much less energy

MIT researchers created protonic programmable resistors — building blocks of analog deep learning systems — that can process data 1 million times faster than synapses in the human brain. These ultrafast, low-energy resistors could enable analog deep learning systems that can train new and more powerful neural networks rapidly, which could be used for areas like self-driving cars, fraud detection, and health care.

Parasites may take a heavier toll on the health of mammal populations than previously thought, study suggests

From cattle to uncontrolled wildlife, pesky but pervasive large parasites like tapeworms have a far greater impact on the total body health of their mammal hosts than previously known, new University of Alberta research suggests.

“Parasites don’t have to kill the animal to control a population,” says Kyle Shanebeck, a Ph.D. student in the Faculty of Science’s Department of Biological Sciences who led the study.

Shanebeck explained that all wildlife have at least one and often multiple . The less fatal a parasite, the more prevalent it is within a population, with potentially stronger negative effects.

Ever heard about bio-weapons that use DNA to kill specific person? They are reality now

A U.S. House Intelligence Committee member cautioned that bioweapons using a target’s DNA to kill only that individual are being created. US Representative Jason Crow of Colorado spoke on Friday at the Aspen Security Forum and cautioned Americans not to be too careless about sharing their DNA with private firms due to the impending arrival of the new type of weapon. “You can target a biological weapon that will kill that person or take them off the battlefield or make them inoperable,” Crow said. “You can take someone’s DNA, you know, take their medical profile,” he added.

Given the prevalence of DNA testing services, where customers voluntarily share their genetic mapping with companies to learn more about their ancestry and health, the congressman said it is concerning that these weapons are being developed. Although 23andMe has maintained time and time again that it does not sell its customers’ private information, it is one of many DNA companies that have done so when asked by the police.

As a member of the Senate Armed Services Committee, US Senator Joni Ernst of Iowa claimed that the US’s adversaries may deploy such DNA bioweapons to attack food supply on a large scale. Ernst forewarned that specific animals relied upon by civilians, armies, or towns could be the target of biological weapons, resulting in scarcity and food poverty and weakening populations.

DJI releases new firmware update for Phantom 4 Multispectral drone

Designed for precision agriculture and environmental management use cases, the P4 Multispectral drone combines data from six separate sensors to measure the health of crops. It can be used to monitor everything from individual plants to entire fields, as well as weeds, insects, and a variety of soil conditions.

The P4 Multispectral drone is compatible with standard industry workflows including flight programming, mapping, and analytics software from DJI and other leading providers. Using the DJI GS Pro application, you can create automated and repeatable missions including flight planning, mission execution, and flight data management. Data collected can be easily imported into DJI Terra or a suite of third-party software including Pix4D Mapper and DroneDeploy, for analysis and to generate additional vegetation index maps.

The drone was first announced in 2019.

WHO declares rapidly spreading monkeypox outbreak a global health emergency

Tedros said the risk posed by monkeypox is moderate globally, but the threat is high in Europe. There’s clearly a risk that the virus will continue to spread around the world, he said, though it’s unlikely to disrupt global trade or travel right now.

In early May, the United Kingdom reported a case of monkeypox in a person who recently returned from travel to Nigeria. Several days later, the U.K. reported three more cases of monkeypox in people who appeared to have become infected locally. Other European nations, Canada and the U.S. then also began confirming cases. It’s unclear where the outbreak actually began.

The WHO last issued a global health emergency in January 2020 in response to the Covid-19 outbreak and two months later declared it a pandemic. The WHO has no official process to declare a pandemic under its organizational laws, which means the term is loosely defined. In 2020, the agency declared Covid a pandemic in an effort to warn complacent governments about the “alarming levels of spread and severity” of the virus.

UN health agency chief declares monkeypox a global emergency

LONDON (AP) — The chief of the World Health Organization said the expanding monkeypox outbreak in more than 70 countries is an “extraordinary” situation that now qualifies as a global emergency, a declaration Saturday that could spur further investment in treating the once-rare disease and worsen the scramble for scarce vaccines.

WHO Director-General Tedros Adhanom Ghebreyesus made the decision to issue the declaration despite a lack of consensus among experts serving on the U.N. health agency’s emergency committee. It was the first time the chief of the U.N. health agency has taken such an action.

“We have an outbreak that has spread around the world rapidly through new modes of transmission about which we understand too little and which meets the criteria in the international health regulations,” Tedros said.

COVID-19 Rebound after Taking Paxlovid Likely Due to Insufficient Drug Exposure

Paxlovid is the leading oral medication for preventing severe cases of COVID-19 in high-risk individuals. However, symptoms returned in some patients after treatment was completed, prompting the Centers for Disease Control and Prevention (CDC) to issue a health advisory on this so-called “COVID-19 rebound.”

In a study published June 20, 2022 in Clinical Infectious Diseases, researchers at University of California San Diego School of Medicine evaluated one such patient and found their symptom relapse was not caused by the development of resistance to the drug or impaired immunity against the virus. Rather, the COVID-19 rebound appears to have been the result of insufficient exposure to the drug.

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