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Implantable heart technology is being used in Manchester to assess when a patient is at high risk of dying, thanks to an NIHR ARC-GM and University of Manchester led research published today.

The pacemakers and defibrillators contain multiple sensors that allow continuous monitoring of a patient’s heart health, 24 hours a day. The study published in Europace and funded by the Medical Research Council is a collaboration between The University of Manchester, Manchester University NHS Foundation Trust (MFT), Health Innovation Manchester, the National Institute for Health Applied Research Collaboration Greater Manchester (ARC-GM) and Medtronic – who manufacture implantable devices.

The research team examined remotely monitored health related data from 439 patients at Manchester Royal Infirmary over two years. The study reported a three-fold increase in odds of mortality for patients who spent at least one day in high-risk status. There was also a 26% increase in the odds of mortality for patients who had 14 consecutive days or more in a high-risk status compared with those whose high-risk episodes were shorter. Higher percentages of time spent in a high-risk status, and less time in a low-risk status, were also associated with increased risk of death.

China could soon outlaw all the news media outlets that are not directly funded by the Communist Party. China’s top economic planner has unveiled a new proposal that would bar private investment in news-related entities. China says that it is proposing to ban private investments to control “unlawful news media-related businesses”. Beijing is preparing to exercise greater control over the news industry, which is already heavily regulated. The current crackdown comes in the midst of a campaign by Xi Jinping to limit the power of private businesses.
#ChinaMediaBan #ChinaCrackdown #Xijinping.

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“Lower levels of DHA are associated with inflammation, cardiovascular and brain disorders, such as depression, which are all linked to migraine risk.”

Professor Nyholt said LPE(20:4) was a chemical compound that blocked the production of an anti-inflammatory molecule called anandamide.


Summary: Researchers have identified causal genetic links to three blood metabolite levels that increase migraine risks.

Source: Queensland University of Technology

Migraines are a pain in the head and in the hip pocket, but newly discovered genetic causes by QUT researchers could lead the way to new preventative drugs and therapies.

Genetic analyses findings were published in The American Journal of Human Genetics by Professor Dale Nyholt and his PhD candidates Hamzeh Tanha and Anita Sathyanarayanan, all from the QUT Centre for Genomics and Personalised Health.

In the United States, animal health authorities are now on high alert. The US Department of Agriculture has pledged an emergency appropriation of $500 million to ramp up surveillance and keep the disease from crossing borders. African swine fever is so feared internationally that, if it were found in the US, pork exports—worth more than $7 billion a year—would immediately shut down.

“Long-distance transboundary spread of highly contagious and pathogenic diseases is a worse-case scenario,” Michael Ward, an epidemiologist and chair of veterinary public health at the University of Sydney, told WIRED by email. “In agriculture, it’s the analogue of Covid-19.”

As with the Covid pandemic at its start, there is no vaccine—but also as with Covid, there is the glimmer of hope for one, thanks to basic science that has been laying down findings for years without receiving much attention. Two weeks ago, a multinational team led by scientists at the USDA’s Agricultural Research Service announced that they had achieved a vaccine candidate, based on a weakened version of the virus with a key gene deleted, and demonstrated its effectiveness in a field trial, in pigs, in Vietnam.

How feasible is it to build a Jupiter brain, a computer the size of a planet? Just in the past few decades, the amount of computational power that’s available to humanity has increased dramatically. Your smartphone is millions of times more powerful than the NASA computers used to send astronauts to the moon on the Apollo 11 mission in 1969. Computers have become integral to our lives, becoming the backbone of our communications, finances, education, art, health care, military, and entertainment. In fact, it would be hard to find an area of our lives that computers didn’t affect.

Now imagine that one day we make a computer that’s the size of an entire planet. And we’re not talking Earth, but larger, a megastructure the size of a gas giant like Jupiter. What would be the implications for humans to operate a computer that size, with an absolutely enormous, virtually limitless, amount of computing power? How would our lives change? One certainly begins to conjure up the transformational effects of having so much oomph, from energy generation to space travel and colonization to a fundamental change in the lifespan and abilities of future humans.

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Endocrine disrupting chemicals cause adverse effects in animals. But limited scientific information exists on potential health problems in humans. Because people are typically exposed to multiple at the same time, assessing public health effects is difficult.


Many chemicals, both natural and man-made, may mimic or interfere with the body’s hormones, known as the endocrine system. Called endocrine disruptors, these chemicals are linked with developmental, reproductive, brain, immune, and other problems.

Endocrine disruptors are found in many everyday products, including some plastic bottles and containers, liners of metal food cans, detergents, flame retardants, food, toys, cosmetics, and pesticides.

Some endocrine-disrupting chemicals are slow to break-down in the environment. That characteristic makes them potentially hazardous over time.

Creating Smart Home Ecosystems — Enabling Health & Well-Being In Every Home — Viren Shah, VP & Chief Digital Officer, GE Appliances, Haier


Mr. Viren Shah is Vice President & Chief Digital Officer, at GE Appliances (GEA — https://www.geappliances.com/), the American home appliance manufacturer, now a majority owned subsidiary of the Chinese multinational home appliances company, Haier (https://www.haierappliances.com/).

Mr. Shah has been with GEA since October 2,018 in which time he was appointed to lead the business through a digital transformation with a focus on data/intelligence at the center of gravity.

Prior to becoming part of the Haier company, Mr. Shah was the CIO at Masco Cabinetry, and CIO Council Leader for their parent company, Masco Corporation, the international conglomerate manufacturer of products for the home improvement and new home construction markets.

Mr. Shah has more than 20 years of global experience in creating business value using technology with a strong focus on customers for Fortune 10 organizations, such as his decade at the Walmart organization. He has contributed as a senior leader towards the success of startups, turnarounds and global mergers and acquisitions.

As the medical community’s understanding of the application of augmented intelligence (AI) in health care grows, there remains the question of how AI—often called artificial intelligence—should be incorporated into physician training. The term augmented intelligence is preferred because it recognizes the enhancement, rather than replacement, of human capabilities.

Understanding how AI can affect patients may help learners appreciate its relevance, he noted, adding that the National Board of Medical Examiners exam now tests physicians-in-training on health systems science, and there are questions about health care AI specifically.

But AI doesn’t just relate to systems issues. It also has a home within evidence-based medicine (EBM).

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“Understandably, there have also been many who have been concerned about fitting new content into already overcrowded curricula,” Dr. James said. This can include figuring out who on the faculty will take on teaching new content.

A slew of new studies now shows that the area of the brain responsible for initiating this action — the primary motor cortex, which controls movement — has as many as 116 different types of cells that work together to make this happen.

The 17 studies, appearing online Oct. 6 in the journal Nature, are the result of five years of work by a huge consortium of researchers supported by the National Institutes of Health’s Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative to identify the myriad of different cell types in one portion of the brain. It is the first step in a long-term project to generate an atlas of the entire brain to help understand how the neural networks in our head control our body and mind and how they are disrupted in cases of mental and physical problems.

“If you think of the brain as an extremely complex machine, how could we understand it without first breaking it down and knowing the parts?” asked cellular neuroscientist Helen Bateup, a University of California, Berkeley, associate professor of molecular and cell biology and co-author of the flagship paper that synthesizes the results of the other papers. “The first page of any manual of how the brain works should read: Here are all the cellular components, this is how many of them there are, here is where they are located and who they connect to.”