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Category: genetics – Page 479

2017 begins on Monday in Vancouver, Canada, and will explore the theme “The Future You.” If the future you is anything like the future us, you are likely curled up in a big cushy chair right now, devouring the contents of a book that flips your thinking. Below, some reading suggestions from the speaker program. Read, enjoy and stay tuned to the TED Blog for beat-by-beat coverage of the conference.

TED2017 begins on Monday in Vancouver, Canada, and will explore the theme “The Future You.” If the future you is anything like the future us, you are likely curled up in a big cushy chair right now, devouring the contents of a book that flips your thinking. Below, some reading suggestions from the speaker program. Read, enjoy and stay tuned to the TED Blog for beat-by-beat coverage of the conference.

Weapons of Math Destruction: How Big Data Increases Inequality and Threatens Democracy by Cathy O’Neil. The decisions that affect our lives are no longer made by humans — they’re made by algorithms. This might sound like a great way around bias and discrimination, but these things are often built right into our mathematical models. When it comes to college admissions, decisions on parole, applications to jobs and the affects of a bad credit score, O’Neil explores the unintended consequences of algorithms. (Read an excerpt.)

The Telomere Effect: A Revolutionary Approach to Living Younger, Healthier, Longer by Elizabeth Blackburn and Elissa Epel. Molecular biologist Elizabeth Blackburn received the Nobel Prize in Medicine for her discovery of telomeres, the ends of chromosomes that — like shoelace tips — keep our genetic information from fraying. Both telomeres and telomerase, an enzyme that restores worn-down telomeres, appear central to the aging process. This book looks at the research — then turns its attention to how our thoughts, bodies and social worlds affect us on the cellular level.

Continue reading “15 books to browse ahead of TED2017” | >

Primarily talking about CRISPR.

Daisy Robinton explores bioengineering and its potential to end ageing.

“The use of gene-editing technology paired with the dropping cost of genome sequencing and analysis is greatly facilitating our ability to understand the functional and mechanistic impact of those genetic mutations on diseases caused by mutations in DNA sequence,” she says.

ABOUT WIRED HEALTH 2017
Hundreds of healthcare, pharmaceutical and technology influencers and leaders met at the fifth annual WIRED Health event at 30 Euston Square, London on March 9. Discover some of the fascinating insights from the esteemed speakers here: http://wired.uk/O6xMxJ

ABOUT WIRED EVENTS
WIRED events shine a spotlight on the innovators, inventors and entrepreneurs who are changing our world for the better. Explore this channel for videos showing on-stage talks, behind-the-scenes action, exclusive interviews and performances from our roster of events. Join us as we uncover the most relevant, up-and-coming trends and meet the people building the future.

ABOUT WIRED
WIRED brings you the future as it happens — the people, the trends, the big ideas that will change our lives. An award-winning printed monthly and online publication. WIRED is an agenda-setting magazine offering brain food on a wide range of topics, from science, technology and business to pop-culture and politics.

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  • An advisory council has urged the U.S. to establish a new body that creates plans for national biodefense and to set aside a $2 billion standby fund to address emerging bioterror threats.
  • As gene editing technology advances, the potential for its use as a weapon increases, and preparing for such threats before they happen is of the utmost importance.

Though the technology promises seemingly innumerable ways to positively impact human life, gene editing is truly a double-edged sword, with nearly as many potentially negative consequences as benefits. Now, an advisory council to President Obama is urging the government to start creating countermeasures for the negative use of emerging biotechnologies.

This month, the President’s Council of Advisors on Science and Technology (PCAST) wrote a letter to President Obama recommending measures to address this potential for harm using new technologies. It advocates funding new research into antibiotic and antiviral drugs to combat resistance and having a $250 million fund for the stockpiling of vaccines.

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The controversial laboratory tool known as CRISPR may have found a whole new world to conquer. Already the favored method of editing genes, CRISPR could soon become a low-cost diagnostic tool that could be used practically anywhere to determine if someone has an infectious disease such as Zika or dengue.

The controversial gene-editing tool may be able to identify infections reliably for pennies in places without electricity.

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New one from Liz.

Full Video ► https://goo.gl/tHvTF5
BioViva ► http://bioviva-science.com

Liz Parrish is the Founder and CEO of BioViva Sciences USA Inc. BioViva is committed to extending healthy lifespans using gene therapy. Liz is known as “the woman who wants to genetically engineer you,” she is a humanitarian, entrepreneur and innovator and a leading voice for genetic cures. As a strong proponent of progress and education for the advancement of gene therapy, she serves as a motivational speaker to the public at large for the life sciences. She is actively involved in international educational media outreach and sits on the board of the International Longevity Alliance (ILA). She is the founder of BioTrove Investments LLC and the BioTrove Podcasts which is committed to offering a meaningful way for people to learn about and fund research in regenerative medicine. She is also the Secretary of the American Longevity Alliance (ALA) a 501©(3) nonprofit trade association that brings together individuals, companies, and organizations who work in advancing the emerging field of cellular & regenerative medicine with the aim to get governments to consider aging a disease.

Continue reading “Liz Parrish — Human of the Future” | >

Technically, an animal could use RNA editing to change the nature of its proteins without completely altering the underlying DNA instructions. This makes the cephalopods’ ability to do it a very interesting phenomenon, but it’s unclear as to why the species requires this much RNA editing. Many of the edited proteins were found in the animals’ brains, which is why scientists think the editing and their brainpower could be linked.

More than any other species on earth, octopuses are particularly smart—they can solve puzzles, use tools, and communicate using color. Now scientists are saying they’re also capable of editing their RNA.

A team of scientists led by Joshua Rosenthal at the Marine Biological Laboratory and Noa Liscovitch-Braur and Eli Eisenberg at Tel Aviv University have discovered that octopuses and squid are capable of a type of genetic alteration called RNA editing. The process is rare among other species, leading scientists to believe that the cephalopods have evolved to follow a special kind of gene recoding.

Normally, living creatures use the information contained in DNA to make proteins, and RNA is the go-between, simply transmitting the message in the DNA. More than 60 percent of RNA transcripts in squid are recoded by editing, and similar levels of RNA editing were identified in other cephalopod species, including two octopuses and a cuttlefish. This changes the message that gets sent out, which in turn changes the proteins that get produced. In comparison, other species like fruit flies and humans experience recoding events only a fraction of one percent of the time. But exactly how the gene editing mechanics work is a mystery.

Continue reading “These Species Can Recode Their Own Genetics” | >

Carriers of the mutation are essentially playing catch-up for their entire lives.

Any night owls reading this will be familiar with the struggle of constantly trying to fit into a morning person’s world. And now researchers say they’ve finally identified the genetic typo that causes this social jetlag.

A new study has revealed that many people who stay up late and struggle to wake up in the morning aren’t lazy, their internal clock is simply genetically programmed to run between 2 and 2.5 hours slower than the rest of the population, thanks to a mutation in a body clock gene called CRY1.

“Carriers of the mutation have longer days than the planet gives them, so they are essentially playing catch-up for their entire lives,” says lead researcher Alina Patke from The Rockefeller University in New York.

Continue reading “Scientists Have Pinpointed the Annoying Genetic Mutation That Turns Us Into Night Owls” | >