Lifeboat Foundation

Scientists from the University of Exeter believe it may be possible to avoid developing dementia, and there are 5 ways that can help to reduce the risk, findings were presented at the Alzheimer’s Association International Conference.

As published in the journal JAMA living a healthy lifestyle may help reduce the risk of dementia even if you have a genetic risk; risk of dementia in those with a higher genetic risk who followed a healthy lifestyle were found to be at 32% lower risk than those with an unhealthy lifestyle.

Data was studied from 196,383 adults of European ancestry who were 60+ years old; 1,769 cases of dementia were identified over an 8 years follow up period; those with high genetic risk and an unhealthy lifestyle were found to be almost 3 times more likely to develop dementia.

https://www.prweb.com/releases/regenerage_international_iime…449142.htm

You OWN your DNA data Let’s keep it that way.

EDNA Members monetize their genetic data by selling access to their data direct to researchers. With an average selling price of $350.00 and an average expectancy of up to 200 deals, this can translate to as much as $70,000.00 per person. Intended use and licensing of this data is controlled by smart contract and may include posted bonds provided by researchers to insure confidentiality and security of the data. Don’t give away this highly-valuable property. Claim it for yourself. Opt-In only when YOU decide. It’s your property and you should be in control.

Two important developers of the celebrated Crispr gene-editing technology said they will make it easier for researchers to license their intellectual property, a move aimed at hastening innovation in the burgeoning field.

MilliporeSigma, the life-sciences tools division of German pharmaceutical giant Merck KGaA, and the Broad Institute of MIT and Harvard said researchers will be able to get nonexclusive rights to patents held by both organizations for research purposes with a single license.

Companies will have to pay a licensing fee. Nonprofit and academic institutions will be permitted to license the patents for free, the organizations said in a news release on Thursday.

Researchers from RMIT University have drawn inspiration from optogenetics, an emerging tool in biotechnology, to develop a device that replicates the way the brain stores and loses information. Optogenetics allows scientists to delve into the body’s electrical system with incredible precision, using light to manipulate neurons so that they can be turned on or off.

The new chip is based on an ultra-thin material that changes electrical resistance in response to different wavelengths of light, enabling it to mimic the way neurons work to store and delete information in the brain. Research team leader Dr. Sumeet Walia said the technology has applications in artificial intelligence (AI) technology that can harness the brain’s full sophisticated functionality.

“Our optogenetically-inspired chip imitates the fundamental biology of nature’s best computer—the human brain,” Walia said. “Being able to store, delete and process information is critical for computing, and the brain does this extremely efficiently. We’re able to simulate the brain’s neural approach simply by shining different colors onto our chip. This technology takes us further on the path towards fast, efficient and secure light-based computing. It also brings us an important step closer to the realization of a bionic brain—a brain-on-a-chip that can learn from its environment just like humans do.”

A University of California, Berkeley professor stands at the front of the room, delivering her invited talk about the potential of genetic engineering. Her audience, full of organic farming advocates, listens uneasily. She notices a man get up from his seat and move toward the front of the room. Confused, the speaker pauses mid-sentence as she watches him bend over, reach for the power cord, and unplug the projector. The room darkens and silence falls. So much for listening to the ideas of others.

Many organic advocates claim that genetically engineered crops are harmful to human health, the environment, and the farmers who work with them. Biotechnology advocates fire back that genetically engineered crops are safe, reduce insecticide use, and allow farmers in developing countries to produce enough food to feed themselves and their families.

Now, sides are being chosen about whether the new gene editing technology, CRISPR, is really just “GMO 2.0” or a helpful new tool to speed up the plant breeding process. In July, the European Union’s Court of Justice ruled that crops made with CRISPR will be classified as genetically engineered. In the United States, meanwhile, the regulatory system is drawing distinctions between genetic engineering and specific uses of genome editing.

In genetics and developmental biology, somatic cell nuclear transfer (SCNT) is a laboratory technique for creating an ovum with a donor nucleus. It can be used in embryonic stem cell research, or in regenerative medicine where it is sometimes referred to as “therapeutic cloning”.

https://www.biointeractive.org/classroom-resources/somatic-c…94yzh8K2uw

Researchers at Tufts University and the Chinese Academy of Sciences have developed a new lipid nanoparticle which can deliver CRISPR/Cas9 gene editing tools into organs with high efficiency, suggesting that the system is promising for clinical applications.

The CRISPR/Cas9 system is currently being investigated as a way to treat a variety of diseases with a genetic basis, including Duchenne muscular dystrophy, Huntington’s, and sickle cell disease. While the system has significant promise, there are some issues that need to be resolved before it can be used clinically. CRISPR/Cas9 is a large complex, and it is difficult to get it inside cell nuclei where it is needed for gene editing.

Scientists have tried a variety of delivery vehicles for CRISPR/Cas, which are intended to carry the gene editing tools to their location and help them enter the cell and nucleus. These have included viruses and various types of nanoparticle. However, to date, these have suffered from low efficiency, whereby very little of the delivered agent reaches the cells or organs where it is needed.

This atlas of human CoRSIVs,” they write, “provides a resource for future population-based investigations into how interindividual epigenetic variation modulates risk of disease,” and may well transform understanding of the causes of illness in the human body.

A project 370 times larger than the Human Genome Project bears first fruit. Stephen Fleischfresser reports.